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Murcko scaffold

Ring system with 3 rings and 24 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
7
With full pages
1
Scaffold SMILES

O=C(C=Cc1ccccc1)NCC1(c2ccccc2)CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)NCC1(c2ccccc2)CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

N-((4-Phenyltetrahydro-2H-pyran-4-yl)methyl)cinnamamide chemical structure, C21H23NO2, CAS 355820-75-6
N-((4-Phenyltetrahydro-2H-pyran-4-yl)methyl)cinnamamide
CAS 355820-75-6C21H23NO2
(E)-3-(4-Chlorophenyl)-N-[(4-phenyloxan-4-yl)methyl]prop-2-enamide chemical structure, C21H22ClNO2, CAS 355820-65-4
(E)-3-(4-Chlorophenyl)-N-[(4-phenyloxan-4-yl)methyl]prop-2-enamide
CAS 355820-65-4C21H22ClNO2
(E)-3-(3,4-Dimethoxyphenyl)-N-((4-phenyltetrahydro-2H-pyran-4-yl)methyl)acrylamide chemical structure, C23H27NO4, CAS 370583-86-1
(E)-3-(3,4-Dimethoxyphenyl)-N-((4-phenyltetrahydro-2H-pyran-4-yl)methyl)acrylamide
CAS 370583-86-1C23H27NO4
(E)-3-(4-Bromophenyl)-N-[(4-phenyloxan-4-yl)methyl]prop-2-enamide chemical structure, C21H22BrNO2, CAS 512795-79-8
(E)-3-(4-Bromophenyl)-N-[(4-phenyloxan-4-yl)methyl]prop-2-enamide
CAS 512795-79-8C21H22BrNO2
(E)-3-(2-Chlorophenyl)-N-((4-(2-methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)acrylamide chemical structure, C22H24ClNO3, CAS 1251711-52-0
(E)-3-(2-Chlorophenyl)-N-((4-(2-methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)acrylamide
CAS 1251711-52-0C22H24ClNO3
(E)-3-(4-(Methylthio)phenyl)-N-((4-phenyltetrahydro-2H-pyran-4-yl)methyl)acrylamide chemical structure, C22H25NO2S, CAS 1627464-85-0
(E)-3-(4-(Methylthio)phenyl)-N-((4-phenyltetrahydro-2H-pyran-4-yl)methyl)acrylamide
CAS 1627464-85-0C22H25NO2S
(E)-N-((4-(2-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)-3-(4-(methylthio)phenyl)acrylamide chemical structure, C23H27NO3S, CAS 1798423-72-9
(E)-N-((4-(2-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)methyl)-3-(4-(methylthio)phenyl)acrylamide
CAS 1798423-72-9C23H27NO3S