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Murcko scaffold

Ring system with 7 rings and 46 atoms

17 chemicals on CompoundList share this ring system.

Rings: 7
Scaffold atoms: 46
Chemicals: 17
With full pages: 0

Scaffold SMILES

O=C(COc1ccccc1)Nc1ncnc2c1ncn2C1CCC(COC(c2ccccc2)(c2ccccc2)c2ccccc2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(COc1ccccc1)Nc1ncnc2c1ncn2C1CCC(COC(c2ccccc2)(c2ccccc2)c2ccccc2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

N-(9-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)-2-phenoxyacetamide chemical structure, C39H37N5O8, CAS 121076-16-2

N-(9-((2R,3R,4S,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)-2-phenoxyacetamide

CAS 121076-16-2C₃₉H₃₇N₅O₈

N-[9-[(2R,3R,4R,5R)-5-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]purin-6-yl]-2-phenoxyacetamide chemical structure, C45H51N5O8Si, CAS 121058-83-1

N-[9-[(2R,3R,4R,5R)-5-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]purin-6-yl]-2-phenoxyacetamide

CAS 121058-83-1C₄₅H₅₁N₅O₈Si

5'-O-DMT-PAC-dA chemical structure, C39H37N5O7, CAS 110522-82-2

5'-O-DMT-PAC-dA

CAS 110522-82-2C₃₉H₃₇N₅O₇

DMT-dA(PAc) Phosphoramidite chemical structure, C48H54N7O8P, CAS 110543-74-3

DMT-dA(PAc) Phosphoramidite

CAS 110543-74-3C₄₈H₅₄N₇O₈P

2'-OTBS A(pac) amidite chemical structure, C54H68N7O9PSi, CAS 121058-86-4

2'-OTBS A(pac) amidite

CAS 121058-86-4C₅₄H₆₈N₇O₉PSi

Starbld0010200 chemical structure, C48H54N7O8P, CAS 142131-03-1

CAS 142131-03-1C₄₈H₅₄N₇O₈P

5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine chemical structure, C40H39N5O8, CAS 128219-81-8

5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine

CAS 128219-81-8C₄₀H₃₉N₅O₈

2'-OMe PAC Abeta-cyanoethyl phosphoramidite chemical structure, C49H56N7O9P, CAS 128219-82-9

2'-OMe PAC Abeta-cyanoethyl phosphoramidite

CAS 128219-82-9C₄₉H₅₆N₇O₉P

2-OPivOM A(pac) amidite chemical structure, C54H64N7O11P, CAS 1097131-21-9

2-OPivOM A(pac) amidite

CAS 1097131-21-9C₅₄H₆₄N₇O₁₁P

Dmt-2/'O-tbdms-RA(tac) amidite 0.5G AB chemical structure, C58H76N7O9PSi, CAS 149989-64-0

Dmt-2/'O-tbdms-RA(tac) amidite 0.5G AB

CAS 149989-64-0C₅₈H₇₆N₇O₉PSi

Adenosine,5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[[4-(1,1-dimethylethyl)phenoxy]acetyl]-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite] chemical structure, C52H62N7O8P, CAS 149989-58-2

Adenosine,5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[[4-(1,1-dimethylethyl)phenoxy]acetyl]-, 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]

CAS 149989-58-2C₅₂H₆₂N₇O₈P

5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite chemical structure, C49H56N7O9P, CAS 145520-30-5

5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite

CAS 145520-30-5C₄₉H₅₆N₇O₉P

N6-methyl-A-CE phosphoramidite chemical structure, C55H70N7O9PSi, CAS 2638447-43-3

N6-methyl-A-CE phosphoramidite

CAS 2638447-43-3C₅₅H₇₀N₇O₉PSi

N-[9-[(2R,3R,4R,5R)-5-[[Bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-3-methoxy-tetrahydrofuran-2-yl]purin-6-yl]-2-phenoxy-N-prop-2-ynyl-acetamide chemical structure, C52H58N7O9P, CAS 3063853-51-7

N-[9-[(2R,3R,4R,5R)-5-[[Bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-3-methoxy-tetrahydrofuran-2-yl]purin-6-yl]-2-phenoxy-N-prop-2-ynyl-acetamide

CAS 3063853-51-7C₅₂H₅₈N₇O₉P

Orb3237707 chemical structure, C50H58N7O9P, CAS 2690324-66-2

CAS 2690324-66-2C₅₀H₅₈N₇O₉P

Ethyl (2E)-2-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-2-[6-[(2-phenoxyacetyl)amino]purin-9-yl]tetrahydrofuran-3-yl]oxyiminopropanoate chemical structure, C53H61N8O11P, CAS 2621967-13-1

Ethyl (2E)-2-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-2-[6-[(2-phenoxyacetyl)amino]purin-9-yl]tetrahydrofuran-3-yl]oxyiminopropanoate

CAS 2621967-13-1C₅₃H₆₁N₈O₁₁P

(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-(2-phenoxyacetamido)-9H-purin-9-yl)-4-((6-(2,2,2-trifluoroacetamido)hexyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite chemical structure, C56H66F3N8O10P, CAS 912641-93-1

(2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-(2-phenoxyacetamido)-9H-purin-9-yl)-4-((6-(2,2,2-trifluoroacetamido)hexyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

CAS 912641-93-1C₅₆H₆₆F₃N₈O₁₀P