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Murcko scaffold

Ring system with 4 rings and 20 atoms

3 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
3
With full pages
1
Scaffold SMILES

c1ccc(Nc2ncnc3ccc4ncsc4c23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2ncnc3ccc4ncsc4c23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 3 of 3 chemicals

9-((2,4-Dichlorophenyl)amino)thiazolo[5,4-f]quinazoline-2-carbonitrile chemical structure, C16H7Cl2N5S, CAS 1425946-13-9
9-((2,4-Dichlorophenyl)amino)thiazolo[5,4-f]quinazoline-2-carbonitrile
CAS 1425946-13-9C16H7Cl2N5S
Methyl 9-((2-fluoro-4-methoxyphenyl)amino)thiazolo[5,4-f]quinazoline-2-carbimidate chemical structure, C18H14FN5O2S, CAS 1425945-60-3
Methyl 9-((2-fluoro-4-methoxyphenyl)amino)thiazolo[5,4-f]quinazoline-2-carbimidate
CAS 1425945-60-3C18H14FN5O2S
Methyl 9-(2,4-dichloroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate chemical structure, C17H11Cl2N5OS, CAS 1425945-63-6
Methyl 9-(2,4-dichloroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate
CAS 1425945-63-6C17H11Cl2N5OS