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Murcko scaffold

Ring system with 3 rings and 25 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
12
With full pages
3
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc(S(=O)(=O)N2CCCCCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccc(S(=O)(=O)N2CCCCCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

4-(Azepan-1-ylsulfonyl)-N-(4-methoxyphenyl)benzamide chemical structure, C20H24N2O4S, CAS 667902-32-1
4-(Azepan-1-ylsulfonyl)-N-(4-methoxyphenyl)benzamide
CAS 667902-32-1C20H24N2O4S
4-(Azepan-1-ylsulfonyl)-N-(3-ethoxyphenyl)benzamide chemical structure, C21H26N2O4S, CAS 307326-32-5
4-(Azepan-1-ylsulfonyl)-N-(3-ethoxyphenyl)benzamide
CAS 307326-32-5C21H26N2O4S
4-(Azepan-1-ylsulfonyl)-N-(3,5-bis(trifluoromethyl)phenyl)benzamide chemical structure, C21H20F6N2O3S, CAS 690249-90-2
4-(Azepan-1-ylsulfonyl)-N-(3,5-bis(trifluoromethyl)phenyl)benzamide
CAS 690249-90-2C21H20F6N2O3S
4-(Azepan-1-ylsulfonyl)-N-[3-(difluoromethylsulfonyl)phenyl]benzamide chemical structure, C20H22F2N2O5S2, CAS 690249-91-3
4-(Azepan-1-ylsulfonyl)-N-[3-(difluoromethylsulfonyl)phenyl]benzamide
CAS 690249-91-3C20H22F2N2O5S2
4-(Azepan-1-ylsulfonyl)-N-(2,4-dimethoxyphenyl)benzamide chemical structure, C21H26N2O5S, CAS 851289-01-5
4-(Azepan-1-ylsulfonyl)-N-(2,4-dimethoxyphenyl)benzamide
CAS 851289-01-5C21H26N2O5S
4-(Azepan-1-ylsulfonyl)-N-(4-ethoxyphenyl)benzamide chemical structure, C21H26N2O4S, CAS 307326-30-3
4-(Azepan-1-ylsulfonyl)-N-(4-ethoxyphenyl)benzamide
CAS 307326-30-3C21H26N2O4S
4-(Azepan-1-ylsulfonyl)-N-(2-(difluoromethoxy)phenyl)benzamide chemical structure, C20H22F2N2O4S, CAS 887198-91-6
4-(Azepan-1-ylsulfonyl)-N-(2-(difluoromethoxy)phenyl)benzamide
CAS 887198-91-6C20H22F2N2O4S
4-(Azepan-1-ylsulfonyl)-N-(2-cyanophenyl)benzamide chemical structure, C20H21N3O3S, CAS 397280-33-0
4-(Azepan-1-ylsulfonyl)-N-(2-cyanophenyl)benzamide
CAS 397280-33-0C20H21N3O3S
4-(Azepan-1-ylsulfonyl)-N-(4-sulfamoylphenyl)benzamide chemical structure, C19H23N3O5S2, CAS 681250-48-6
4-(Azepan-1-ylsulfonyl)-N-(4-sulfamoylphenyl)benzamide
CAS 681250-48-6C19H23N3O5S2
4-(Azepan-1-ylsulfonyl)-N-[2-(2-cyanoethylsulfanyl)phenyl]benzamide chemical structure, C22H25N3O3S2, CAS 477497-89-5
4-(Azepan-1-ylsulfonyl)-N-[2-(2-cyanoethylsulfanyl)phenyl]benzamide
CAS 477497-89-5C22H25N3O3S2
4-(Azepan-1-ylsulfonyl)-N-(5-ethylsulfonyl-2-hydroxyphenyl)benzamide chemical structure, C21H26N2O6S2, CAS 852712-48-2
4-(Azepan-1-ylsulfonyl)-N-(5-ethylsulfonyl-2-hydroxyphenyl)benzamide
CAS 852712-48-2C21H26N2O6S2
4-(Azepan-1-ylsulfonyl)-N-(3,5-dichlorophenyl)benzamide chemical structure, C19H20Cl2N2O3S, CAS 681250-71-5
4-(Azepan-1-ylsulfonyl)-N-(3,5-dichlorophenyl)benzamide
CAS 681250-71-5C19H20Cl2N2O3S