Murcko scaffold
Ring system with 5 rings and 27 atoms
4 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 27
- Chemicals
- 4
- With full pages
- 3
Scaffold SMILES
c1ccc(-c2nnc(OCc3nc4ccccc4[nH]3)c3ccccc23)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold c1ccc(-c2nnc(OCc3nc4ccccc4[nH]3)c3ccccc23)cc1](/scaffold/QJFVGLSGALVKNG-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 4 of 4 chemicals
![1-[(1-Methylbenzimidazol-2-yl)methoxy]-4-phenylphthalazine chemical structure, C23H18N4O, CAS 332390-45-1](/s/XZAIZSZNYJEPKN-UHFFFAOYSA-N.svg)
1-[(1-Methylbenzimidazol-2-yl)methoxy]-4-phenylphthalazine
CAS 332390-45-1C23H18N4O
![1-(4-Chlorophenyl)-4-[(1-methylbenzimidazol-2-yl)methoxy]phthalazine chemical structure, C23H17ClN4O, CAS 381711-86-0](/s/CXSYPOATTFHAPS-UHFFFAOYSA-N.svg)
1-(4-Chlorophenyl)-4-[(1-methylbenzimidazol-2-yl)methoxy]phthalazine
CAS 381711-86-0C23H17ClN4O
![1-[(1-Methylbenzimidazol-2-yl)methoxy]-4-(4-methylphenyl)phthalazine chemical structure, C24H20N4O, CAS 374600-09-6](/s/NKUSJCRAWUTATK-UHFFFAOYSA-N.svg)
1-[(1-Methylbenzimidazol-2-yl)methoxy]-4-(4-methylphenyl)phthalazine
CAS 374600-09-6C24H20N4O
![N,N-Dimethyl-4-[4-[(1-methylbenzimidazol-2-yl)methoxy]phthalazin-1-yl]benzamide chemical structure, C26H23N5O2, CAS 374911-34-9](/s/BTYXJAKVYJFPBW-UHFFFAOYSA-N.svg)
N,N-Dimethyl-4-[4-[(1-methylbenzimidazol-2-yl)methoxy]phthalazin-1-yl]benzamide
CAS 374911-34-9C26H23N5O2