CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 25 atoms

6 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
25
Chemicals
6
With full pages
2
Scaffold SMILES

O=C(C=Cc1ccccc1)NCCCNC(=O)C=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)NCCCNC(=O)C=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

(E)-3-(4-Methylphenyl)-N-[3-[[(E)-3-(4-methylphenyl)prop-2-enoyl]amino]propyl]prop-2-enamide chemical structure, C23H26N2O2, CAS 548440-32-0
(E)-3-(4-Methylphenyl)-N-[3-[[(E)-3-(4-methylphenyl)prop-2-enoyl]amino]propyl]prop-2-enamide
CAS 548440-32-0C23H26N2O2
N,N'-(Propane-1,3-diyl)bis(3-(4-isopropylphenyl)acrylamide) chemical structure, C27H34N2O2, CAS 548431-83-0
N,N'-(Propane-1,3-diyl)bis(3-(4-isopropylphenyl)acrylamide)
CAS 548431-83-0C27H34N2O2
Tyrphostin AG 537 chemical structure, C23H20N4O6, CAS 140674-77-7
Tyrphostin AG 537
CAS 140674-77-7C23H20N4O6
(E)-2-Cyano-N-[3-[[(E)-2-cyano-3-(3,4,5-trihydroxyphenyl)prop-2-enoyl]amino]propyl]-3-(3,4,5-trihydroxyphenyl)prop-2-enamide chemical structure, C23H20N4O8, CAS 171674-76-3
(E)-2-Cyano-N-[3-[[(E)-2-cyano-3-(3,4,5-trihydroxyphenyl)prop-2-enoyl]amino]propyl]-3-(3,4,5-trihydroxyphenyl)prop-2-enamide
CAS 171674-76-3C23H20N4O8
3-(3,4-Dimethoxyphenyl)-N-(3-{[3-(3,4-dimethoxyphenyl)acryloyl]amino}propyl)acrylamide chemical structure, C25H30N2O6, CAS 16873-96-4
3-(3,4-Dimethoxyphenyl)-N-(3-{[3-(3,4-dimethoxyphenyl)acryloyl]amino}propyl)acrylamide
CAS 16873-96-4C25H30N2O6
N1,N5-di-[(E)-p-coumaroyl]-spermidine chemical structure, C25H31N3O4, CAS 114916-04-0
N1,N5-di-[(E)-p-coumaroyl]-spermidine
CAS 114916-04-0C25H31N3O4