Murcko scaffold
Ring system with 6 rings and 23 atoms
35 chemicals on CompoundList share this ring system.
- Rings
- 6
- Scaffold atoms
- 23
- Chemicals
- 35
- With full pages
- 3
Scaffold SMILES
O=C(OCC1c2ccccc2-c2ccccc21)N1CC2CC1C2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 35 of 35 chemicals
![2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(trifluoromethyl)-2-azabicyclo[2.1.1]hexane-1-carboxylic acid chemical structure, C22H18F3NO4, CAS 1986905-35-4](/s/MZLZXYVDQPYTHX-UHFFFAOYSA-N.svg)
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(trifluoromethyl)-2-azabicyclo[2.1.1]hexane-1-carboxylic acid
CAS 1986905-35-4C22H18F3NO4
![2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-1,4-dicarboxylic acid chemical structure, C22H19NO6, CAS 1993277-26-1](/s/FNOQHCLBWLRWEI-UHFFFAOYSA-N.svg)
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-1,4-dicarboxylic acid
CAS 1993277-26-1C22H19NO6
![2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-fluoro-2-azabicyclo[2.1.1]hexane-1-carboxylic acid chemical structure, C21H18FNO4, CAS 1936244-94-8](/s/MVTDJLYCVGPUBO-UHFFFAOYSA-N.svg)
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-fluoro-2-azabicyclo[2.1.1]hexane-1-carboxylic acid
CAS 1936244-94-8C21H18FNO4
![2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-1-carboxylic acid chemical structure, C21H19NO4, CAS 1936396-62-1](/s/JMVXIHLJJFHMKW-UHFFFAOYSA-N.svg)
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-1-carboxylic acid
CAS 1936396-62-1C21H19NO4
![2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-5-carboxylic acid chemical structure, C21H19NO4, CAS 1936346-32-5](/s/ANMAHERDPHGACL-UHFFFAOYSA-N.svg)
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-5-carboxylic acid
CAS 1936346-32-5C21H19NO4
2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-methyl-2-azabicyclo(2.1.1)hexane-1-carboxylic acid
CAS 2002257-09-0C22H21NO4
![2-(2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexan-1-yl)acetic acid chemical structure, C22H21NO4, CAS 2138239-40-2](/s/JQYPBJVFNYTBCB-UHFFFAOYSA-N.svg)
2-(2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexan-1-yl)acetic acid
CAS 2138239-40-2C22H21NO4
![2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1-(hydroxymethyl)-2-azabicyclo[2.1.1]hexane-4-carboxylic acid chemical structure, C22H21NO5, CAS 2757917-39-6](/s/AGRQWVLXMUJTMX-UHFFFAOYSA-N.svg)
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1-(hydroxymethyl)-2-azabicyclo[2.1.1]hexane-4-carboxylic acid
CAS 2757917-39-6C22H21NO5
![rac-(1R,3R,4S,5S)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-3-methyl-2-azabicyclo[2.1.1]hexane-5-carboxylic acid chemical structure, C22H21NO4, CAS 2803354-21-2](/s/CJVUAHKVFPBEPC-OBGLBDJTSA-N.svg)
rac-(1R,3R,4S,5S)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-3-methyl-2-azabicyclo[2.1.1]hexane-5-carboxylic acid
CAS 2803354-21-2C22H21NO4
![3-(2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexan-1-yl)propanoic acid chemical structure, C23H23NO4, CAS 2137791-32-1](/s/TUVWKBZEXHVHTR-UHFFFAOYSA-N.svg)
3-(2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexan-1-yl)propanoic acid
CAS 2137791-32-1C23H23NO4
![rac-(1R,4S,5S)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-5-carboxylic acid chemical structure, C21H19NO4, CAS 2138003-97-9](/s/ANMAHERDPHGACL-YXKWSERDSA-N.svg)
rac-(1R,4S,5S)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-5-carboxylic acid
CAS 2138003-97-9C21H19NO4
![rac-(1R,4S,5S)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-5-methyl-2-azabicyclo[2.1.1]hexane-1-carboxylic acid chemical structure, C22H21NO4, CAS 2138151-10-5](/s/AFNQOJBINFKHLT-QLEMLULZSA-N.svg)
rac-(1R,4S,5S)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-5-methyl-2-azabicyclo[2.1.1]hexane-1-carboxylic acid
CAS 2138151-10-5C22H21NO4
![2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-4-carboxylic acid chemical structure, C21H19NO4, CAS 2344685-89-6](/s/BCLMPGULXNIOGR-UHFFFAOYSA-N.svg)
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-4-carboxylic acid
CAS 2344685-89-6C21H19NO4
![2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(hydroxymethyl)-2-azabicyclo[2.1.1]hexane-1-carboxylic acid chemical structure, C22H21NO5, CAS 2580183-62-4](/s/PWVRBYAAGZDJEV-UHFFFAOYSA-N.svg)
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(hydroxymethyl)-2-azabicyclo[2.1.1]hexane-1-carboxylic acid
CAS 2580183-62-4C22H21NO5
![rac-(1R,4S,5R)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-5-carboxylic acid chemical structure, C21H19NO4, CAS 2580097-90-9](/s/ANMAHERDPHGACL-QQGDVQBRSA-N.svg)
rac-(1R,4S,5R)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-5-carboxylic acid
CAS 2580097-90-9C21H19NO4
![(1R,4S,5S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-5-carboxylic acid chemical structure, C21H19NO4, CAS 2639390-47-7](/s/ANMAHERDPHGACL-DPMMWBKBSA-N.svg)
(1R,4S,5S)-2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-5-carboxylic acid
CAS 2639390-47-7C21H19NO4
![2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-3-carboxylic acid chemical structure, C21H19NO4, CAS 1176024-56-8](/s/VXXSJMZTYSLGNT-UHFFFAOYSA-N.svg)
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-3-carboxylic acid
CAS 1176024-56-8C21H19NO4
![4-(Difluoromethyl)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-1-carboxylic acid chemical structure, C22H19F2NO4, CAS 2639422-65-2](/s/WBHMAMULPUIBQU-UHFFFAOYSA-N.svg)
4-(Difluoromethyl)-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-1-carboxylic acid
CAS 2639422-65-2C22H19F2NO4
![2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(methoxymethyl)-2-azabicyclo[2.1.1]hexane-1-carboxylic acid chemical structure, C23H23NO5, CAS 2680725-65-7](/s/BHYLIIUYNXWRMO-UHFFFAOYSA-N.svg)
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(methoxymethyl)-2-azabicyclo[2.1.1]hexane-1-carboxylic acid
CAS 2680725-65-7C23H23NO5
![2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(methoxycarbonyl)-2-azabicyclo[2.1.1]hexane-1-carboxylic acid chemical structure, C23H21NO6, CAS 2763928-76-1](/s/KETVQBSESLEVTA-UHFFFAOYSA-N.svg)
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(methoxycarbonyl)-2-azabicyclo[2.1.1]hexane-1-carboxylic acid
CAS 2763928-76-1C23H21NO6
![2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-methyl-2-azabicyclo[2.1.1]hexane-1-carboxylic acid chemical structure, C22H21NO4, CAS 2763914-69-6](/s/NRVSWXQFCDCIER-UHFFFAOYSA-N.svg)
2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-methyl-2-azabicyclo[2.1.1]hexane-1-carboxylic acid
CAS 2763914-69-6C22H21NO4
![(9H-Fluoren-9-yl)methyl 4-ethyl-1-(hydroxymethyl)-2-azabicyclo[2.1.1]hexane-2-carboxylate chemical structure, C23H25NO3, CAS 2763946-25-2](/s/HDNOOTQCJIWJEM-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl 4-ethyl-1-(hydroxymethyl)-2-azabicyclo[2.1.1]hexane-2-carboxylate
CAS 2763946-25-2C23H25NO3
![(9H-Fluoren-9-yl)methyl 4-(hydroxymethyl)-2-azabicyclo[2.1.1]hexane-2-carboxylate chemical structure, C21H21NO3, CAS 2764020-50-8](/s/QAQZGCLWZBMVQQ-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl 4-(hydroxymethyl)-2-azabicyclo[2.1.1]hexane-2-carboxylate
CAS 2764020-50-8C21H21NO3
![(9H-Fluoren-9-yl)methyl 1-(hydroxymethyl)-4-(methoxymethyl)-2-azabicyclo[2.1.1]hexane-2-carboxylate chemical structure, C23H25NO4, CAS 2764013-65-0](/s/ZPUXXXBEVSJTBI-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl 1-(hydroxymethyl)-4-(methoxymethyl)-2-azabicyclo[2.1.1]hexane-2-carboxylate
CAS 2764013-65-0C23H25NO4
- (9H-Fluoren-9-yl)methyl 1-(hydroxymethyl)-4-methyl-2-azabicyclo[2.1.1]hexane-2-carboxylate2763956-33-6C22H23NO3
- (9H-Fluoren-9-yl)methyl 1-(hydroxymethyl)-2-azabicyclo[2.1.1]hexane-2-carboxylate2001758-13-8C21H21NO3
- (9H-Fluoren-9-yl)methyl 4-(hydroxymethyl)-1-(methoxymethyl)-2-azabicyclo[2.1.1]hexane-2-carboxylate2763985-21-1C23H25NO4
- (9H-Fluoren-9-yl)methyl 4-hydroxy-2-azabicyclo[2.1.1]hexane-2-carboxylate2763939-94-0C20H19NO3
- (9H-Fluoren-9-yl)methyl 1-cyano-2-azabicyclo[2.1.1]hexane-2-carboxylate2770525-61-4C21H18N2O2
- 2-(9H-Fluoren-9-yl)methyl 4-methyl 1-(hydroxymethyl)-2-azabicyclo[2.1.1]hexane-2,4-dicarboxylate2770486-57-0C23H23NO5
- 2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1-(methoxymethyl)-2-azabicyclo[2.1.1]hexane-4-carboxylic acid2757927-33-4C23H23NO5
- 4-Ethyl-2-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2-azabicyclo[2.1.1]hexane-1-carboxylic acid2757901-63-4C23H23NO4
- (9H-Fluoren-9-yl)methyl 1-ethynyl-2-azabicyclo[2.1.1]hexane-2-carboxylate2770530-15-7C22H19NO2
- 2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1-(methoxycarbonyl)-2-azabicyclo[2.1.1]hexane-4-carboxylic acid2913409-62-6C23H21NO6
- 2-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1-(fluoromethyl)-2-azabicyclo[2.1.1]hexane-4-carboxylic acid3017211-06-9C22H20FNO4