Murcko scaffold
7-Phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine scaffold
17 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 18
- Chemicals
- 17
- With full pages
- 2
Scaffold SMILES
c1ccc(-n2ncc3c2ncn2cnnc32)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 17 of 17 chemicals
![7-(4-Chlorophenyl)-3-methyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C13H9ClN6, CAS 845628-10-6](/s/NNEXLHRDZFMNFT-UHFFFAOYSA-N.svg)
7-(4-Chlorophenyl)-3-methyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
CAS 845628-10-6C13H9ClN6
![3-(3,4-Dimethylphenyl)-7-methyl-6-hydropyrazolo[5,4-d]1,2,4-triazolo[4,3-e]pyr imidine chemical structure, C15H14N6, CAS 845801-36-7](/s/RTPZQAQLMZEROC-UHFFFAOYSA-N.svg)
3-(3,4-Dimethylphenyl)-7-methyl-6-hydropyrazolo[5,4-d]1,2,4-triazolo[4,3-e]pyr imidine
CAS 845801-36-7C15H14N6
![7-(3,4-Dimethylphenyl)-3-ethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C16H16N6, CAS 845900-14-3](/s/OSKHDDWTEHZENL-UHFFFAOYSA-N.svg)
7-(3,4-Dimethylphenyl)-3-ethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
CAS 845900-14-3C16H16N6
![7-(4-Fluorophenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C12H7FN6, CAS 844458-50-0](/s/OUBRJIOFFZRUFE-UHFFFAOYSA-N.svg)
7-(4-Fluorophenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
CAS 844458-50-0C12H7FN6
![7-(2,4-Dimethylphenyl)-3-ethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C16H16N6, CAS 845635-83-8](/s/DYYMSWFHPPDFKU-UHFFFAOYSA-N.svg)
7-(2,4-Dimethylphenyl)-3-ethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
CAS 845635-83-8C16H16N6
![7-(3-Chloro-4-methylphenyl)-3-methyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C14H11ClN6, CAS 845665-83-0](/s/SHLJROSXMVHECW-UHFFFAOYSA-N.svg)
7-(3-Chloro-4-methylphenyl)-3-methyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
CAS 845665-83-0C14H11ClN6
![7-(3,4-Dichlorophenyl)-3-ethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C14H10Cl2N6, CAS 846028-77-1](/s/NZCSFHJITIJDED-UHFFFAOYSA-N.svg)
7-(3,4-Dichlorophenyl)-3-ethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
CAS 846028-77-1C14H10Cl2N6
![3-tert-Butyl-7-(3,4-dimethylphenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C18H20N6, CAS 847245-69-6](/s/QGBCLOVLEQKRDZ-UHFFFAOYSA-N.svg)
3-tert-Butyl-7-(3,4-dimethylphenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
CAS 847245-69-6C18H20N6
![7-(3,4-Dichlorophenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C12H6Cl2N6, CAS 846586-83-2](/s/HMHUTZIYFOFOCX-UHFFFAOYSA-N.svg)
7-(3,4-Dichlorophenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
CAS 846586-83-2C12H6Cl2N6
![7-Phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C12H8N6, CAS 302936-32-9](/s/QSFYGYPZUVQYMC-UHFFFAOYSA-N.svg)
7-Phenyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
CAS 302936-32-9C12H8N6
![10-(3-Chlorophenyl)-5-ethyl-3,4,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaene chemical structure, C14H11ClN6, CAS 846593-83-7](/s/BHLYCGRTPDJSIS-UHFFFAOYSA-N.svg)
10-(3-Chlorophenyl)-5-ethyl-3,4,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaene
CAS 846593-83-7C14H11ClN6
![7-(2,4-Dimethylphenyl)-3-methyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C15H14N6, CAS 846597-30-6](/s/GXXJCKZPNMYFIU-UHFFFAOYSA-N.svg)
7-(2,4-Dimethylphenyl)-3-methyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
CAS 846597-30-6C15H14N6
![10-(5-Chloro-2-methylphenyl)-3,4,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaene chemical structure, C13H9ClN6, CAS 847377-64-4](/s/CTTKEKXMMCHMOR-UHFFFAOYSA-N.svg)
10-(5-Chloro-2-methylphenyl)-3,4,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaene
CAS 847377-64-4C13H9ClN6
![7-(2,4-Dimethylphenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C14H12N6, CAS 848683-68-1](/s/OKQINOPLYNPCNN-UHFFFAOYSA-N.svg)
7-(2,4-Dimethylphenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
CAS 848683-68-1C14H12N6
![7-(4-Chlorophenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C12H7ClN6, CAS 848736-51-6](/s/OIJSCOSNZZQDPP-UHFFFAOYSA-N.svg)
7-(4-Chlorophenyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
CAS 848736-51-6C12H7ClN6
![7-(3-Chloro-4-methylphenyl)-3-ethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine chemical structure, C15H13ClN6, CAS 848739-58-2](/s/ZENITZBITPUIFN-UHFFFAOYSA-N.svg)
7-(3-Chloro-4-methylphenyl)-3-ethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[4,3-c]pyrimidine
CAS 848739-58-2C15H13ClN6
![2-{[10-(3,4-Dichlorophenyl)-3,4,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-5-yl]sulfanyl}acetamide chemical structure, C14H9Cl2N7OS, CAS 842968-29-0](/s/OTAQJPMANMAGOS-UHFFFAOYSA-N.svg)
2-{[10-(3,4-Dichlorophenyl)-3,4,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-5-yl]sulfanyl}acetamide
CAS 842968-29-0C14H9Cl2N7OS
Related scaffolds
Same ring framework with different atoms or bond orders
