CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 23 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
8
With full pages
2
Scaffold SMILES

O=C(Nc1cccc(-c2nn3cnnc3s2)c1)c1cccnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccc(-c2nn3cnnc3s2)c1)c1cccnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N-[2-Methyl-5-(3-methyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)phenyl]-3-pyridinecarboxamide chemical structure, C17H14N6OS, CAS 797767-66-9
N-[2-Methyl-5-(3-methyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)phenyl]-3-pyridinecarboxamide
CAS 797767-66-9C17H14N6OS
N-[3-(3-Methyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)phenyl]nicotinamide chemical structure, C16H12N6OS, CAS 797781-75-0
N-[3-(3-Methyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)phenyl]nicotinamide
CAS 797781-75-0C16H12N6OS
2-Chloro-N-[3-(3-methyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)phenyl]pyridine-3-carboxamide chemical structure, C16H11ClN6OS, CAS 847471-29-8
2-Chloro-N-[3-(3-methyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)phenyl]pyridine-3-carboxamide
CAS 847471-29-8C16H11ClN6OS
N-[5-(3-Ethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)-2-methylphenyl]pyridine-3-carboxamide chemical structure, C18H16N6OS, CAS 895337-58-3
N-[5-(3-Ethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)-2-methylphenyl]pyridine-3-carboxamide
CAS 895337-58-3C18H16N6OS
N-[3-(3-Ethyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)phenyl]nicotinamide chemical structure, C17H14N6OS, CAS 892673-83-5
N-[3-(3-Ethyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)phenyl]nicotinamide
CAS 892673-83-5C17H14N6OS
N-(2-Methyl-5-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-ylphenyl)nicotinamide chemical structure, C16H12N6OS, CAS 919028-60-7
N-(2-Methyl-5-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-ylphenyl)nicotinamide
CAS 919028-60-7C16H12N6OS
5-Bromo-N-[5-(3-ethyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)-2-methoxyphenyl]nicotinamide chemical structure, C18H15BrN6O2S, CAS 925595-60-4
5-Bromo-N-[5-(3-ethyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)-2-methoxyphenyl]nicotinamide
CAS 925595-60-4C18H15BrN6O2S
N-[5-(3-Ethyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)-2-methoxyphenyl]nicotinamide chemical structure, C18H16N6O2S, CAS 925166-10-5
N-[5-(3-Ethyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)-2-methoxyphenyl]nicotinamide
CAS 925166-10-5C18H16N6O2S