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Murcko scaffold

Ring system with 5 rings and 22 atoms

10 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
22
Chemicals
10
With full pages
4
Scaffold SMILES

O=C(NN=Cc1ccccc1)NC12CC3CC(CC(C3)C1)C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)NC12CC3CC(CC(C3)C1)C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1-(1-Adamantyl)-3-[(4-hydroxy-3-methoxyphenyl)methylideneamino]urea chemical structure, C19H25N3O3
1-(1-Adamantyl)-3-[(4-hydroxy-3-methoxyphenyl)methylideneamino]urea
C19H25N3O3
N-(Adamantan-1-yl)-2-(2-methoxybenzylidene)hydrazine-1-carboxamide chemical structure, C19H25N3O2, CAS 310438-31-4
N-(Adamantan-1-yl)-2-(2-methoxybenzylidene)hydrazine-1-carboxamide
CAS 310438-31-4C19H25N3O2
1-(1-Adamantyl)-3-[(E)-(2-nitrophenyl)methylideneamino]urea chemical structure, C18H22N4O3, CAS 324062-47-7
1-(1-Adamantyl)-3-[(E)-(2-nitrophenyl)methylideneamino]urea
CAS 324062-47-7C18H22N4O3
1-(1-Adamantyl)-3-[(E)-(4-nitrophenyl)methylideneamino]urea chemical structure, C18H22N4O3, CAS 324042-85-5
1-(1-Adamantyl)-3-[(E)-(4-nitrophenyl)methylideneamino]urea
CAS 324042-85-5C18H22N4O3
1-(1-Adamantyl)-3-[(Z)-(4-bromophenyl)methylideneamino]urea chemical structure, C18H22BrN3O, CAS 324062-50-2
1-(1-Adamantyl)-3-[(Z)-(4-bromophenyl)methylideneamino]urea
CAS 324062-50-2C18H22BrN3O
(E)-N-((3s,5s,7s)-Adamantan-1-yl)-2-(4-(isopentyloxy)benzylidene)hydrazinecarboxamide chemical structure, C23H33N3O2, CAS 324062-46-6
(E)-N-((3s,5s,7s)-Adamantan-1-yl)-2-(4-(isopentyloxy)benzylidene)hydrazinecarboxamide
CAS 324062-46-6C23H33N3O2
(2E)-2-(3,4-Dihydroxybenzylidene)-N-(tricyclo[3.3.1.1~3,7~]dec-1-yl)hydrazinecarboxamide chemical structure, C18H23N3O3, CAS 5662-71-5
(2E)-2-(3,4-Dihydroxybenzylidene)-N-(tricyclo[3.3.1.1~3,7~]dec-1-yl)hydrazinecarboxamide
CAS 5662-71-5C18H23N3O3
1-(1-Adamantyl)-3-[[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]urea chemical structure, C18H23N3O2, CAS 324036-96-6
1-(1-Adamantyl)-3-[[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]urea
CAS 324036-96-6C18H23N3O2
1-(1-Adamantyl)-3-[(E)-(4-hydroxy-3-methoxyphenyl)methylideneamino]urea chemical structure, C19H25N3O3, CAS 348590-58-9
1-(1-Adamantyl)-3-[(E)-(4-hydroxy-3-methoxyphenyl)methylideneamino]urea
CAS 348590-58-9C19H25N3O3
1-(1-Adamantyl)-3-[(E)-(4-hydroxyphenyl)methylideneamino]urea chemical structure, C18H23N3O2, CAS 324062-42-2
1-(1-Adamantyl)-3-[(E)-(4-hydroxyphenyl)methylideneamino]urea
CAS 324062-42-2C18H23N3O2