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Murcko scaffold

Ring system with 3 rings and 25 atoms

23 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
23
With full pages
4
Scaffold SMILES

O=C(Nc1ccccc1)C(=Cc1ccccc1)NC(=O)c1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)C(=Cc1ccccc1)NC(=O)c1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

N-[1-(4-Chlorophenyl)-3-(4-methoxyanilino)-3-oxoprop-1-en-2-yl]furan-2-carboxamide chemical structure, C21H17ClN2O4, CAS 353483-94-0
N-[1-(4-Chlorophenyl)-3-(4-methoxyanilino)-3-oxoprop-1-en-2-yl]furan-2-carboxamide
CAS 353483-94-0C21H17ClN2O4
3-(3-Bromophenyl)-2-(furan-2-ylformamido)-N-(4-methylphenyl)prop-2-enamide chemical structure, C21H17BrN2O3, CAS 304000-84-8
3-(3-Bromophenyl)-2-(furan-2-ylformamido)-N-(4-methylphenyl)prop-2-enamide
CAS 304000-84-8C21H17BrN2O3
3-(3-Bromophenyl)-2-(furan-2-ylformamido)-N-(4-methoxyphenyl)prop-2-enamide chemical structure, C21H17BrN2O4, CAS 304000-88-2
3-(3-Bromophenyl)-2-(furan-2-ylformamido)-N-(4-methoxyphenyl)prop-2-enamide
CAS 304000-88-2C21H17BrN2O4
2-(Furan-2-ylformamido)-N,3-bis(4-methoxyphenyl)prop-2-enamide chemical structure, C22H20N2O5, CAS 304000-68-8
2-(Furan-2-ylformamido)-N,3-bis(4-methoxyphenyl)prop-2-enamide
CAS 304000-68-8C22H20N2O5
N-[(E)-3-Anilino-3-oxo-1-phenylprop-1-en-2-yl]furan-2-carboxamide chemical structure, C20H16N2O3, CAS 69763-54-8
N-[(E)-3-Anilino-3-oxo-1-phenylprop-1-en-2-yl]furan-2-carboxamide
CAS 69763-54-8C20H16N2O3
(2Z)-2-(Furan-2-ylformamido)-N-(3-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-enamide chemical structure, C21H18N2O5, CAS 304000-72-4
(2Z)-2-(Furan-2-ylformamido)-N-(3-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-enamide
CAS 304000-72-4C21H18N2O5
2-(Furan-2-ylformamido)-3-(4-methoxyphenyl)-N-phenylprop-2-enamide chemical structure, C21H18N2O4, CAS 69763-56-0
2-(Furan-2-ylformamido)-3-(4-methoxyphenyl)-N-phenylprop-2-enamide
CAS 69763-56-0C21H18N2O4
(2Z)-N-(3-Acetylphenyl)-2-(furan-2-ylformamido)-3-(4-methoxyphenyl)prop-2-enamide chemical structure, C23H20N2O5, CAS 304000-74-6
(2Z)-N-(3-Acetylphenyl)-2-(furan-2-ylformamido)-3-(4-methoxyphenyl)prop-2-enamide
CAS 304000-74-6C23H20N2O5
3-(4-Bromophenyl)-2-(furan-2-ylformamido)-N-(4-methoxyphenyl)prop-2-enamide chemical structure, C21H17BrN2O4, CAS 304000-24-6
3-(4-Bromophenyl)-2-(furan-2-ylformamido)-N-(4-methoxyphenyl)prop-2-enamide
CAS 304000-24-6C21H17BrN2O4
N-[1-(4-Fluorophenyl)-3-(4-iodoanilino)-3-oxoprop-1-en-2-yl]furan-2-carboxamide chemical structure, C20H14FIN2O3, CAS 4678-41-5
N-[1-(4-Fluorophenyl)-3-(4-iodoanilino)-3-oxoprop-1-en-2-yl]furan-2-carboxamide
CAS 4678-41-5C20H14FIN2O3
N-[(E)-3-Anilino-1-(3-nitrophenyl)-3-oxoprop-1-en-2-yl]-5-bromofuran-2-carboxamide chemical structure, C20H14BrN3O5, CAS 327101-50-8
N-[(E)-3-Anilino-1-(3-nitrophenyl)-3-oxoprop-1-en-2-yl]-5-bromofuran-2-carboxamide
CAS 327101-50-8C20H14BrN3O5
N-[(E)-3-(4-Acetylanilino)-1-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]furan-2-carboxamide chemical structure, C23H20N2O5, CAS 332107-06-9
N-[(E)-3-(4-Acetylanilino)-1-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]furan-2-carboxamide
CAS 332107-06-9C23H20N2O5
N-[(E)-3-(4-Methylanilino)-3-oxo-1-phenylprop-1-en-2-yl]furan-2-carboxamide chemical structure, C21H18N2O3, CAS 69763-55-9
N-[(E)-3-(4-Methylanilino)-3-oxo-1-phenylprop-1-en-2-yl]furan-2-carboxamide
CAS 69763-55-9C21H18N2O3
N-[(E)-1-(4-Methoxyphenyl)-3-(4-methylanilino)-3-oxoprop-1-en-2-yl]furan-2-carboxamide chemical structure, C22H20N2O4, CAS 304000-62-2
N-[(E)-1-(4-Methoxyphenyl)-3-(4-methylanilino)-3-oxoprop-1-en-2-yl]furan-2-carboxamide
CAS 304000-62-2C22H20N2O4
N-[(E)-3-Anilino-1-(4-bromophenyl)-3-oxoprop-1-en-2-yl]furan-2-carboxamide chemical structure, C20H15BrN2O3, CAS 332106-90-8
N-[(E)-3-Anilino-1-(4-bromophenyl)-3-oxoprop-1-en-2-yl]furan-2-carboxamide
CAS 332106-90-8C20H15BrN2O3
N-[(E)-3-(3-Acetylanilino)-1-(3,4-dimethoxyphenyl)-3-oxoprop-1-en-2-yl]furan-2-carboxamide chemical structure, C24H22N2O6, CAS 693232-35-8
N-[(E)-3-(3-Acetylanilino)-1-(3,4-dimethoxyphenyl)-3-oxoprop-1-en-2-yl]furan-2-carboxamide
CAS 693232-35-8C24H22N2O6
N-[(Z)-1-(4-Bromophenyl)-3-(4-chloroanilino)-3-oxoprop-1-en-2-yl]furan-2-carboxamide chemical structure, C20H14BrClN2O3, CAS 304000-19-9
N-[(Z)-1-(4-Bromophenyl)-3-(4-chloroanilino)-3-oxoprop-1-en-2-yl]furan-2-carboxamide
CAS 304000-19-9C20H14BrClN2O3
N-(3-Acetylphenyl)-2-(furan-2-ylformamido)-3-phenylprop-2-enamide chemical structure, C22H18N2O4, CAS 304000-53-1
N-(3-Acetylphenyl)-2-(furan-2-ylformamido)-3-phenylprop-2-enamide
CAS 304000-53-1C22H18N2O4
3-(4-Fluorophenyl)-2-(furan-2-ylformamido)-N-(3-hydroxyphenyl)prop-2-enamide chemical structure, C20H15FN2O4, CAS 304000-41-7
3-(4-Fluorophenyl)-2-(furan-2-ylformamido)-N-(3-hydroxyphenyl)prop-2-enamide
CAS 304000-41-7C20H15FN2O4
3-(3-Bromophenyl)-2-(furan-2-ylformamido)-N-(2-methoxyphenyl)prop-2-enamide chemical structure, C21H17BrN2O4, CAS 304000-92-8
3-(3-Bromophenyl)-2-(furan-2-ylformamido)-N-(2-methoxyphenyl)prop-2-enamide
CAS 304000-92-8C21H17BrN2O4
N-(3-Chlorophenyl)-2-(furan-2-ylformamido)-3-(4-methoxyphenyl)prop-2-enamide chemical structure, C21H17ClN2O4, CAS 69763-57-1
N-(3-Chlorophenyl)-2-(furan-2-ylformamido)-3-(4-methoxyphenyl)prop-2-enamide
CAS 69763-57-1C21H17ClN2O4
(2Z)-N-(4-Bromophenyl)-3-(4-fluorophenyl)-2-(furan-2-ylformamido)prop-2-enamide chemical structure, C20H14BrFN2O3, CAS 304000-35-9
(2Z)-N-(4-Bromophenyl)-3-(4-fluorophenyl)-2-(furan-2-ylformamido)prop-2-enamide
CAS 304000-35-9C20H14BrFN2O3
N-(4-Chlorophenyl)-3-(4-fluorophenyl)-2-(furan-2-ylformamido)prop-2-enamide chemical structure, C20H14ClFN2O3, CAS 304000-33-7
N-(4-Chlorophenyl)-3-(4-fluorophenyl)-2-(furan-2-ylformamido)prop-2-enamide
CAS 304000-33-7C20H14ClFN2O3