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Murcko scaffold

Ring system with 4 rings and 19 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
8
With full pages
4
Scaffold SMILES

O=C1Nc2cc3ccccc3c3cccc(c23)C1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1Nc2cc3ccccc3c3cccc(c23)C1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Aristolodione chemical structure, C18H13NO4, CAS 109771-09-7
Aristolodione
CAS 109771-09-7C18H13NO4
Cepharadione B chemical structure, C19H15NO4, CAS 55610-02-1
Cepharadione B
CAS 55610-02-1C19H15NO4
Norcepharadione B chemical structure, C18H13NO4, CAS 57576-41-7
Norcepharadione B
CAS 57576-41-7C18H13NO4
4,5-Dioxodehydroasimilobine chemical structure, C17H11NO4, CAS 82644-81-3
4,5-Dioxodehydroasimilobine
CAS 82644-81-3C17H11NO4
Griffinin chemical structure, C19H15NO4, CAS 240122-31-0
Griffinin
CAS 240122-31-0C19H15NO4
Pontevedrine chemical structure, C21H19NO6, CAS 34647-65-9
Pontevedrine
CAS 34647-65-9C21H19NO6
Ouregidione chemical structure, C19H15NO5, CAS 107633-70-5
Ouregidione
CAS 107633-70-5C19H15NO5
7-Chloro-6-demethylcepharadione B chemical structure, C18H12ClNO4, CAS 149682-95-1
7-Chloro-6-demethylcepharadione B
CAS 149682-95-1C18H12ClNO4