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Murcko scaffold

3-Phenylquinolin-4(1H)-one scaffold

45 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
45
With full pages
18
Scaffold SMILES

O=c1c(-c2ccccc2)c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenylquinolin-4(1H)-one page
Murcko scaffold O=c1c(-c2ccccc2)c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 45 of 45 chemicals

2-Methyl-3-phenylquinolin-4(1H)-one chemical structure, C16H13NO, CAS 5350-61-8
2-Methyl-3-phenylquinolin-4(1H)-one
CAS 5350-61-8C16H13NO
3-Phenylquinolin-4(1H)-one chemical structure, C15H11NO, CAS 17052-37-8
3-Phenylquinolin-4(1H)-one
CAS 17052-37-8C15H11NO
N-[3-(4-Methoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]propanamide chemical structure, C20H20N2O3, CAS 883959-66-8
N-[3-(4-Methoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]propanamide
CAS 883959-66-8C20H20N2O3
N-(3-(4-Methoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl)acetamide chemical structure, C19H18N2O3, CAS 883959-62-4
N-(3-(4-Methoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl)acetamide
CAS 883959-62-4C19H18N2O3
Methyl 2-(1-methyl-4-oxo-1,4-dihydro-3-quinolinyl)benzenecarboxylate chemical structure, C18H15NO3, CAS 294184-16-0
Methyl 2-(1-methyl-4-oxo-1,4-dihydro-3-quinolinyl)benzenecarboxylate
CAS 294184-16-0C18H15NO3
2-(6-Chloro-1-methyl-4-oxo-1,4-dihydro-3-quinolinyl)benzenecarboxylic acid chemical structure, C17H12ClNO3, CAS 866135-92-4
2-(6-Chloro-1-methyl-4-oxo-1,4-dihydro-3-quinolinyl)benzenecarboxylic acid
CAS 866135-92-4C17H12ClNO3
2-(6-Chloro-1-methyl-4-oxo-1,4-dihydro-3-quinolinyl)benzenecarboxamide chemical structure, C17H13ClN2O2, CAS 866135-94-6
2-(6-Chloro-1-methyl-4-oxo-1,4-dihydro-3-quinolinyl)benzenecarboxamide
CAS 866135-94-6C17H13ClN2O2
N-(1-Ethyl-4-oxo-3-phenylquinolin-2-yl)-2-methylpropanamide chemical structure, C21H22N2O2, CAS 883961-23-7
N-(1-Ethyl-4-oxo-3-phenylquinolin-2-yl)-2-methylpropanamide
CAS 883961-23-7C21H22N2O2
N-(1-Methyl-4-oxo-3-phenylquinolin-2-yl)propanamide chemical structure, C19H18N2O2, CAS 896855-96-2
N-(1-Methyl-4-oxo-3-phenylquinolin-2-yl)propanamide
CAS 896855-96-2C19H18N2O2
2-Methyl-N-(1-methyl-4-oxo-3-phenyl-1,4-dihydroquinolin-2-yl)propanamide chemical structure, C20H20N2O2, CAS 883960-87-0
2-Methyl-N-(1-methyl-4-oxo-3-phenyl-1,4-dihydroquinolin-2-yl)propanamide
CAS 883960-87-0C20H20N2O2
2-(1,4-Dihydro-1-methyl-4-oxo-3-quinolinyl)benzamide chemical structure, C17H14N2O2, CAS 105576-80-5
2-(1,4-Dihydro-1-methyl-4-oxo-3-quinolinyl)benzamide
CAS 105576-80-5C17H14N2O2
2-(1-Methyl-4-oxo-1,4-dihydro-3-quinolinyl)benzenecarboxylic acid chemical structure, C17H13NO3, CAS 105576-79-2
2-(1-Methyl-4-oxo-1,4-dihydro-3-quinolinyl)benzenecarboxylic acid
CAS 105576-79-2C17H13NO3
N-Methyl-2-(1-methyl-4-oxo-1,4-dihydro-3-quinolinyl)benzenecarboxamide chemical structure, C18H16N2O2, CAS 866041-26-1
N-Methyl-2-(1-methyl-4-oxo-1,4-dihydro-3-quinolinyl)benzenecarboxamide
CAS 866041-26-1C18H16N2O2
N-[1-Methyl-3-(4-methylphenyl)-4-oxoquinolin-2-yl]propanamide chemical structure, C20H20N2O2, CAS 900263-33-4
N-[1-Methyl-3-(4-methylphenyl)-4-oxoquinolin-2-yl]propanamide
CAS 900263-33-4C20H20N2O2
N-[3-(2-Fluorophenyl)-1-methyl-4-oxoquinolin-2-yl]-2-methylpropanamide chemical structure, C20H19FN2O2, CAS 902014-08-8
N-[3-(2-Fluorophenyl)-1-methyl-4-oxoquinolin-2-yl]-2-methylpropanamide
CAS 902014-08-8C20H19FN2O2
2-Methyl-N-[1-methyl-3-(4-methylphenyl)-4-oxoquinolin-2-yl]propanamide chemical structure, C21H22N2O2, CAS 883964-49-6
2-Methyl-N-[1-methyl-3-(4-methylphenyl)-4-oxoquinolin-2-yl]propanamide
CAS 883964-49-6C21H22N2O2
N-[3-(3-Methoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]-2-methylpropanamide chemical structure, C21H22N2O3, CAS 883966-10-7
N-[3-(3-Methoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]-2-methylpropanamide
CAS 883966-10-7C21H22N2O3
N-(3-(3,4-Dimethoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl)acetamide chemical structure, C20H20N2O4, CAS 883956-11-4
N-(3-(3,4-Dimethoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl)acetamide
CAS 883956-11-4C20H20N2O4
N-[3-(2-Chlorophenyl)-1-ethyl-4-oxoquinolin-2-yl]acetamide chemical structure, C19H17ClN2O2, CAS 883963-83-5
N-[3-(2-Chlorophenyl)-1-ethyl-4-oxoquinolin-2-yl]acetamide
CAS 883963-83-5C19H17ClN2O2
N-[1-Methyl-3-(3-methylphenyl)-4-oxoquinolin-2-yl]butanamide chemical structure, C21H22N2O2, CAS 883954-41-4
N-[1-Methyl-3-(3-methylphenyl)-4-oxoquinolin-2-yl]butanamide
CAS 883954-41-4C21H22N2O2
N-[3-(4-Chlorophenyl)-1-methyl-4-oxoquinolin-2-yl]acetamide chemical structure, C18H15ClN2O2, CAS 900869-69-4
N-[3-(4-Chlorophenyl)-1-methyl-4-oxoquinolin-2-yl]acetamide
CAS 900869-69-4C18H15ClN2O2
N-[3-(3-Methoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]propanamide chemical structure, C20H20N2O3, CAS 901271-08-7
N-[3-(3-Methoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]propanamide
CAS 901271-08-7C20H20N2O3
N-[3-(3,4-Dimethoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]-2-methylpropanamide chemical structure, C22H24N2O4, CAS 883965-38-6
N-[3-(3,4-Dimethoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]-2-methylpropanamide
CAS 883965-38-6C22H24N2O4
N-[3-(3,4-Dimethoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]butanamide chemical structure, C22H24N2O4, CAS 883965-36-4
N-[3-(3,4-Dimethoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]butanamide
CAS 883965-36-4C22H24N2O4