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Murcko scaffold

Ring system with 4 rings and 22 atoms

18 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
18
With full pages
5
Scaffold SMILES

O=c1ccn(-c2ccccc2)c2nc(N3CCCC3)ccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn(-c2ccccc2)c2nc(N3CCCC3)ccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

Tosufloxacin chemical structure, C19H15F3N4O3, CAS 100490-36-6
Tosufloxacin
CAS 100490-36-6C19H15F3N4O3
Tosufloxacin tosylate chemical structure, C26H23F3N4O6S, CAS 115964-29-9
Tosufloxacin tosylate
CAS 115964-29-9C26H23F3N4O6S
1,8-Naphthyridine-3-carboxaldehyde, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, monohydrochloride chemical structure, C19H16ClF3N4O2, CAS 134762-03-1
1,8-Naphthyridine-3-carboxaldehyde, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, monohydrochloride
CAS 134762-03-1C19H16ClF3N4O2
7-(4'-Amino-2'-methylpyrrolidinyl)-1-(2,4-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid chemical structure, C20H17F3N4O3, CAS 114676-84-5
7-(4'-Amino-2'-methylpyrrolidinyl)-1-(2,4-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid
CAS 114676-84-5C20H17F3N4O3
1-(2,4-Difluorophenyl)-6-fluoro-7-{3-[(methylamino)methyl]pyrrolidin-1-yl}-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid chemical structure, C21H19F3N4O3, CAS 182869-30-3
1-(2,4-Difluorophenyl)-6-fluoro-7-{3-[(methylamino)methyl]pyrrolidin-1-yl}-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
CAS 182869-30-3C21H19F3N4O3
7-[(3S)-3-Aminopyrrolidin-1-yl]-1-(2,4-difluorophenyl)-6-fluoro-5-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid chemical structure, C20H17F3N4O3, CAS 132195-65-4
7-[(3S)-3-Aminopyrrolidin-1-yl]-1-(2,4-difluorophenyl)-6-fluoro-5-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
CAS 132195-65-4C20H17F3N4O3
RefChem:221883 chemical structure, C20H18ClF3N4O3, CAS 138668-58-3
RefChem:221883
CAS 138668-58-3C20H18ClF3N4O3
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-(3-(methylamino)-1-pyrrolidinyl)-4-oxo-, monohydrochloride, (S)- chemical structure, C21H20ClF3N4O3, CAS 138668-60-7
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-1-(2,4-difluorophenyl)-6-fluoro-5-methyl-7-(3-(methylamino)-1-pyrrolidinyl)-4-oxo-, monohydrochloride, (S)-
CAS 138668-60-7C21H20ClF3N4O3
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-7-(3-amino-1-pyrrolidinyl)-6-fluoro-1-(4-fluorophenyl)-5-methyl-4-oxo-, hydrochloride, hydrate (1:1:1), (S)- chemical structure, C20H19ClF2N4O3, CAS 138668-61-8
1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-7-(3-amino-1-pyrrolidinyl)-6-fluoro-1-(4-fluorophenyl)-5-methyl-4-oxo-, hydrochloride, hydrate (1:1:1), (S)-
CAS 138668-61-8C20H19ClF2N4O3
1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, 4-methylbenzenesulfonate, hydrate (1:1:?) chemical structure, C26H25F3N4O7S, CAS 1400591-39-0
1,8-Naphthyridine-3-carboxylic acid, 7-(3-amino-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, 4-methylbenzenesulfonate, hydrate (1:1:?)
CAS 1400591-39-0C26H25F3N4O7S
(S-(R,S))-7-(3-(1-Aminoethyl)-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid chemical structure, C21H19F3N4O3, CAS 143383-20-4
(S-(R,S))-7-(3-(1-Aminoethyl)-1-pyrrolidinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
CAS 143383-20-4C21H19F3N4O3
Tosufloxacin hydrochloride chemical structure, C19H16ClF3N4O3, CAS 104051-69-6
Tosufloxacin hydrochloride
CAS 104051-69-6C19H16ClF3N4O3
1,8-Naphthyridine-3-carboxylic acid, 1-(5-amino-2-fluorophenyl)-7-[(3S)-3-amino-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo- chemical structure, C19H17F2N5O3, CAS 535170-27-5
1,8-Naphthyridine-3-carboxylic acid, 1-(5-amino-2-fluorophenyl)-7-[(3S)-3-amino-1-pyrrolidinyl]-6-fluoro-1,4-dihydro-4-oxo-
CAS 535170-27-5C19H17F2N5O3
Ethyl 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylate chemical structure, C21H19F3N4O3, CAS 105152-95-2
Ethyl 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylate
CAS 105152-95-2C21H19F3N4O3
PD 140248 chemical structure, C210H201Cl11F30N40O30, CAS 147208-55-7
PD 140248
CAS 147208-55-7C210H201Cl11F30N40O30
Tosufloxacin monohydrate chemical structure, C19H17F3N4O4, CAS 107097-79-0
Tosufloxacin monohydrate
CAS 107097-79-0C19H17F3N4O4
7-[(3R,4R)-3,4-Dihydroxypyrrolidin-1-yl]-6-fluoro-4-oxo-1-(2,4,6-trifluorophenyl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic aci chemical structure, C19H13F4N3O5, CAS 2206667-46-9
7-[(3R,4R)-3,4-Dihydroxypyrrolidin-1-yl]-6-fluoro-4-oxo-1-(2,4,6-trifluorophenyl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic aci
CAS 2206667-46-9C19H13F4N3O5
Orb2646007 chemical structure, C23H17F9N4O4, CAS 2206665-50-9
Orb2646007
CAS 2206665-50-9C23H17F9N4O4