Murcko scaffold
2-(7-Keto-3-phenyl-triazolo[4,5-d]pyrimidin-6-yl)-N-phenethyl-acetamide scaffold
16 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 28
- Chemicals
- 16
- With full pages
- 1
Scaffold SMILES
O=C(Cn1cnc2c(nnn2-c2ccccc2)c1=O)NCCc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 16 of 16 chemicals
![2-(7-Keto-3-phenyl-triazolo[4,5-d]pyrimidin-6-yl)-N-phenethyl-acetamide chemical structure, C20H18N6O2, CAS 863018-69-3](/s/RNVJNCOFVFXREF-UHFFFAOYSA-N.svg)
2-(7-Keto-3-phenyl-triazolo[4,5-d]pyrimidin-6-yl)-N-phenethyl-acetamide
CAS 863018-69-3C20H18N6O2
![2-(3-(4-Fluorophenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide chemical structure, C20H17FN6O2, CAS 892480-64-7](/s/AKWPKSSREDYYFO-UHFFFAOYSA-N.svg)
2-(3-(4-Fluorophenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide
CAS 892480-64-7C20H17FN6O2
![2-(3-(3-Chlorophenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide chemical structure, C20H17ClN6O2, CAS 892481-17-3](/s/XETBYVXTORSIQX-UHFFFAOYSA-N.svg)
2-(3-(3-Chlorophenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide
CAS 892481-17-3C20H17ClN6O2
![2-(3-(4-Methoxyphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide chemical structure, C21H20N6O3, CAS 892481-56-0](/s/JASJRKCOTYHQBJ-UHFFFAOYSA-N.svg)
2-(3-(4-Methoxyphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide
CAS 892481-56-0C21H20N6O3
![2-(3-(4-Ethoxyphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide chemical structure, C22H22N6O3, CAS 912618-03-2](/s/LDIXAXDIFYKHQF-UHFFFAOYSA-N.svg)
2-(3-(4-Ethoxyphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide
CAS 912618-03-2C22H22N6O3
![2-(3-(3-Fluorophenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide chemical structure, C20H17FN6O2, CAS 893935-38-1](/s/IIHWZEGMHFFQFM-UHFFFAOYSA-N.svg)
2-(3-(3-Fluorophenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide
CAS 893935-38-1C20H17FN6O2
![2-(3-(4-Chlorophenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide chemical structure, C20H17ClN6O2, CAS 893942-90-0](/s/XGSQZXVUFWWJPB-UHFFFAOYSA-N.svg)
2-(3-(4-Chlorophenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide
CAS 893942-90-0C20H17ClN6O2
![2-(3-(3,4-Dimethylphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide chemical structure, C22H22N6O2, CAS 893917-49-2](/s/DHGURRXIUMBAGE-UHFFFAOYSA-N.svg)
2-(3-(3,4-Dimethylphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide
CAS 893917-49-2C22H22N6O2
![2-(3-(3-Chlorophenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-(3,4-dimethoxyphenethyl)acetamide chemical structure, C22H21ClN6O4, CAS 863019-66-3](/s/ZGBUWFRRNMRZKH-UHFFFAOYSA-N.svg)
2-(3-(3-Chlorophenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-(3,4-dimethoxyphenethyl)acetamide
CAS 863019-66-3C22H21ClN6O4
![N-(3,4-Dimethoxyphenethyl)-2-(3-(3-fluorophenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamide chemical structure, C22H21FN6O4, CAS 872590-59-5](/s/XQLTXJPUSIQTCQ-UHFFFAOYSA-N.svg)
N-(3,4-Dimethoxyphenethyl)-2-(3-(3-fluorophenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamide
CAS 872590-59-5C22H21FN6O4
![2-[3-(4-Chlorophenyl)-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl]-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide chemical structure, C22H21ClN6O4, CAS 872590-79-9](/s/PNQUDZLZWPGIPK-UHFFFAOYSA-N.svg)
2-[3-(4-Chlorophenyl)-7-oxo-3H,6H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-6-yl]-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide
CAS 872590-79-9C22H21ClN6O4
![2-(3-(3-Chloro-4-methylphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-(3,4-dimethoxyphenethyl)acetamide chemical structure, C23H23ClN6O4, CAS 872594-38-2](/s/ZSFQDFDWCHQAHQ-UHFFFAOYSA-N.svg)
2-(3-(3-Chloro-4-methylphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-(3,4-dimethoxyphenethyl)acetamide
CAS 872594-38-2C23H23ClN6O4
![N-(3,4-Dimethoxyphenethyl)-2-(3-(3,4-dimethoxyphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamide chemical structure, C24H26N6O6, CAS 887214-59-7](/s/UVMATOLYOURISA-UHFFFAOYSA-N.svg)
N-(3,4-Dimethoxyphenethyl)-2-(3-(3,4-dimethoxyphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamide
CAS 887214-59-7C24H26N6O6
![N-(3,4-Dimethoxyphenethyl)-2-(7-oxo-3-(p-tolyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamide chemical structure, C23H24N6O4, CAS 863019-25-4](/s/VYQSEWZMUKEUER-UHFFFAOYSA-N.svg)
N-(3,4-Dimethoxyphenethyl)-2-(7-oxo-3-(p-tolyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamide
CAS 863019-25-4C23H24N6O4
![N-(3,4-Dimethoxyphenethyl)-2-(3-(3,5-dimethylphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamide chemical structure, C24H26N6O4, CAS 893923-14-3](/s/ZKGNPVIABOYSNE-UHFFFAOYSA-N.svg)
N-(3,4-Dimethoxyphenethyl)-2-(3-(3,5-dimethylphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)acetamide
CAS 893923-14-3C24H26N6O4
![2-(3-(3,4-Dimethoxyphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide chemical structure, C22H22N6O4, CAS 893937-71-8](/s/PIHDNCJTSIZLCU-UHFFFAOYSA-N.svg)
2-(3-(3,4-Dimethoxyphenyl)-7-oxo-3H-[1,2,3]triazolo[4,5-d]pyrimidin-6(7H)-yl)-N-phenethylacetamide
CAS 893937-71-8C22H22N6O4
Related scaffolds
Same ring framework with different atoms or bond orders
