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Murcko scaffold

Ring system with 3 rings and 16 atoms

18 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 16
Chemicals: 18
With full pages: 2

Scaffold SMILES

O=C1CCc2cc(B3OCCO3)ccc2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C1CCc2cc(B3OCCO3)ccc2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

3,4-Dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2(1H)-one chemical structure, C15H20BNO3, CAS 400620-72-6

3,4-Dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2(1H)-one

CAS 400620-72-6C₁₅H₂₀BNO₃

8-Chloro-1-methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-1H-quinolin-2-one chemical structure, C16H21BClNO3, CAS 1427588-44-0

8-Chloro-1-methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-1H-quinolin-2-one

CAS 1427588-44-0C₁₆H₂₁BClNO₃

1-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2(1H)-one chemical structure, C16H22BNO3, CAS 1427587-32-3

1-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2(1H)-one

CAS 1427587-32-3C₁₆H₂₂BNO₃

8-Fluoro-1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2(1H)-one chemical structure, C16H21BFNO3, CAS 1427588-39-3

8-Fluoro-1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2(1H)-one

CAS 1427588-39-3C₁₆H₂₁BFNO₃

8-Methyl-2-oxo-1,2,3,4-tetrahydroquinoline-6-boronic Acid Pinacol Ester chemical structure, C16H22BNO3, CAS 2304633-96-1

8-Methyl-2-oxo-1,2,3,4-tetrahydroquinoline-6-boronic Acid Pinacol Ester

CAS 2304633-96-1C₁₆H₂₂BNO₃

7-Fluoro-1-methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-1H-quinolin-2-one chemical structure, C16H21BFNO3, CAS 1427587-55-0

7-Fluoro-1-methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-1H-quinolin-2-one

CAS 1427587-55-0C₁₆H₂₁BFNO₃

1,4,4-Trimethyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-1H-quinolin-2-one chemical structure, C18H26BNO3, CAS 1427587-56-1

1,4,4-Trimethyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-1H-quinolin-2-one

CAS 1427587-56-1C₁₈H₂₆BNO₃

7-Chloro-1-methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-1H-quinolin-2-one chemical structure, C16H21BClNO3, CAS 1427588-30-4

7-Chloro-1-methyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-1H-quinolin-2-one

CAS 1427588-30-4C₁₆H₂₁BClNO₃

8-(1,1-Dimethylethyl)-3,4-dihydro-4,4-dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(1H)-quinolinone chemical structure, C21H32BNO3, CAS 1403387-00-7

8-(1,1-Dimethylethyl)-3,4-dihydro-4,4-dimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(1H)-quinolinone

CAS 1403387-00-7C₂₁H₃₂BNO₃

8-(1,1-Dimethylethyl)-3,4-dihydro-1,4,4-trimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(1H)-quinolinone chemical structure, C22H34BNO3, CAS 1403387-01-8

8-(1,1-Dimethylethyl)-3,4-dihydro-1,4,4-trimethyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(1H)-quinolinone

CAS 1403387-01-8C₂₂H₃₄BNO₃

3,4-Dihydro-7-methoxy-1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(1H)-quinolinone chemical structure, C17H24BNO4, CAS 1647114-87-1

3,4-Dihydro-7-methoxy-1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(1H)-quinolinone

CAS 1647114-87-1C₁₇H₂₄BNO₄

5-Fluoro-1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2(1H)-one chemical structure, C16H21BFNO3, CAS 1914114-73-0

5-Fluoro-1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2(1H)-one

CAS 1914114-73-0C₁₆H₂₁BFNO₃

5-Chloro-1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2(1H)-one chemical structure, C16H21BClNO3, CAS 1914114-74-1

5-Chloro-1-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2(1H)-one

CAS 1914114-74-1C₁₆H₂₁BClNO₃

tert-Butyl 2-oxo-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinoline-1-carboxylate chemical structure, C20H28BNO5, CAS 2241054-71-5

tert-Butyl 2-oxo-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinoline-1-carboxylate

CAS 2241054-71-5C₂₀H₂₈BNO₅

8-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,4-tetrahydroquinolin-2-one chemical structure, C15H19BFNO3, CAS 2377233-77-5

8-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,4-tetrahydroquinolin-2-one

CAS 2377233-77-5C₁₅H₁₉BFNO₃

7-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-1H-quinolin-2-one chemical structure, C15H19BFNO3, CAS 2377233-87-7

7-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-1H-quinolin-2-one

CAS 2377233-87-7C₁₅H₁₉BFNO₃

5-Fluoro-3,4-dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(1H)-quinolinone chemical structure, C15H19BFNO3, CAS 2852822-28-5

5-Fluoro-3,4-dihydro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2(1H)-quinolinone

CAS 2852822-28-5C₁₅H₁₉BFNO₃

1-Isopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2-one chemical structure, C18H26BNO3, CAS 2699091-19-3

1-Isopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2-one

CAS 2699091-19-3C₁₈H₂₆BNO₃