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Murcko scaffold

4-(4-Phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine scaffold

29 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 21
Chemicals: 29
With full pages: 0

Scaffold SMILES

c1ccc(N2CCN(c3ncnc4[nH]ncc34)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 4-(4-Phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine page

Murcko scaffold c1ccc(N2CCN(c3ncnc4[nH]ncc34)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

4-[4-(3-Chlorophenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C15H15ClN6, CAS 565169-26-8

4-[4-(3-Chlorophenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine

CAS 565169-26-8C₁₅H₁₅ClN₆

1-Methyl-4-(4-(4-nitrophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C16H17N7O2, CAS 869073-16-5

1-Methyl-4-(4-(4-nitrophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine

CAS 869073-16-5C₁₆H₁₇N₇O₂

4-(4-(3,4-Dichlorophenyl)piperazin-1-yl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C16H16Cl2N6, CAS 869073-17-6

4-(4-(3,4-Dichlorophenyl)piperazin-1-yl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

CAS 869073-17-6C₁₆H₁₆Cl₂N₆

4-(4-Phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C15H16N6, CAS 871335-81-8

4-(4-Phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine

CAS 871335-81-8C₁₅H₁₆N₆

4-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C17H20N6O, CAS 869072-43-5

4-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidine

CAS 869072-43-5C₁₇H₂₀N₆O

3-Bromo-4-(4-(2-methoxyphenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C16H17BrN6O, CAS 871340-88-4

3-Bromo-4-(4-(2-methoxyphenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine

CAS 871340-88-4C₁₆H₁₇BrN₆O

N-(2-(4-(4-Phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)acetamide chemical structure, C19H23N7O, CAS 1021226-23-2

N-(2-(4-(4-Phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)acetamide

CAS 1021226-23-2C₁₉H₂₃N₇O

2-[4-(4-Phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethan-1-amine chemical structure, C17H21N7, CAS 1105196-33-5

2-[4-(4-Phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethan-1-amine

CAS 1105196-33-5C₁₇H₂₁N₇

2-(4-(4-(4-Fluorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethanamine chemical structure, C17H20FN7, CAS 1105196-35-7

2-(4-(4-(4-Fluorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethanamine

CAS 1105196-35-7C₁₇H₂₀FN₇

N-(2-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-3-methylbutanamide chemical structure, C23H31N7O2, CAS 1021060-88-7

N-(2-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-3-methylbutanamide

CAS 1021060-88-7C₂₃H₃₁N₇O₂

N-(2-(4-(4-(4-Fluorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-3-methylbutanamide chemical structure, C22H28FN7O, CAS 1021094-02-9

N-(2-(4-(4-(4-Fluorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-3-methylbutanamide

CAS 1021094-02-9C₂₂H₂₈FN₇O

2-Ethyl-N-(2-(4-(4-(4-fluorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)butanamide chemical structure, C23H30FN7O, CAS 1021060-91-2

2-Ethyl-N-(2-(4-(4-(4-fluorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)butanamide

CAS 1021060-91-2C₂₃H₃₀FN₇O

4-(4-(4-Nitrophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C15H15N7O2, CAS 1021219-86-2

4-(4-(4-Nitrophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine

CAS 1021219-86-2C₁₅H₁₅N₇O₂

4-(4-(4-Methoxyphenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C16H18N6O, CAS 1021059-88-0

4-(4-(4-Methoxyphenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine

CAS 1021059-88-0C₁₆H₁₈N₆O

4-(4-(2-Chlorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C15H15ClN6, CAS 1021093-09-3

4-(4-(2-Chlorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine

CAS 1021093-09-3C₁₅H₁₅ClN₆

N-(2-(4-(4-(4-Fluorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)acetamide chemical structure, C19H22FN7O, CAS 1172842-60-2

N-(2-(4-(4-(4-Fluorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)acetamide

CAS 1172842-60-2C₁₉H₂₂FN₇O

N-(2-(4-(4-(4-Fluorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-2-methoxyacetamide chemical structure, C20H24FN7O2, CAS 1171756-08-3

N-(2-(4-(4-(4-Fluorophenyl)piperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-2-methoxyacetamide

CAS 1171756-08-3C₂₀H₂₄FN₇O₂

N-{2-[4-(4-Phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethyl}butane-1-sulfonamide chemical structure, C21H29N7O2S, CAS 1172353-73-9

N-{2-[4-(4-Phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]ethyl}butane-1-sulfonamide

CAS 1172353-73-9C₂₁H₂₉N₇O₂S

1-(3-Chlorophenyl)-4-(3-ethyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazine-2-carboxylic acid chemical structure, C18H19ClN6O2, CAS 871336-58-2

1-(3-Chlorophenyl)-4-(3-ethyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazine-2-carboxylic acid

CAS 871336-58-2C₁₈H₁₉ClN₆O₂

3-Bromo-4-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C16H16BrClN6, CAS 871337-05-2

3-Bromo-4-[4-(5-chloro-2-methylphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine

CAS 871337-05-2C₁₆H₁₆BrClN₆

3-Ethyl-4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C17H20N6, CAS 871336-26-4

3-Ethyl-4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine

CAS 871336-26-4C₁₇H₂₀N₆

4-[4-(2-Methylphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C16H18N6, CAS 871335-83-0

4-[4-(2-Methylphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine

CAS 871335-83-0C₁₆H₁₈N₆

4-[4-(5-Chloro-2-methylphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine chemical structure, C16H17ClN6, CAS 871335-84-1

4-[4-(5-Chloro-2-methylphenyl)piperazin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine

CAS 871335-84-1C₁₆H₁₇ClN₆

Methyl 1-(3-chlorophenyl)-4-(3-ethyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazine-2-carboxylate chemical structure, C19H21ClN6O2, CAS 871336-56-0

Methyl 1-(3-chlorophenyl)-4-(3-ethyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazine-2-carboxylate

CAS 871336-56-0C₁₉H₂₁ClN₆O₂