Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 4 rings and 18 atoms

8 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 18
Chemicals: 8
With full pages: 4

Scaffold SMILES

c1ccc2c(c1)nc1cccc(N3CCCC3)n12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc2c(c1)nc1cccc(N3CCCC3)n12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Methyl 3-(4-cyano-3-methyl-1-pyrrolidin-1-ylpyrido[1,2-a]benzimidazol-2-yl)propanoate chemical structure, C21H22N4O2, CAS 844859-78-5

Methyl 3-(4-cyano-3-methyl-1-pyrrolidin-1-ylpyrido[1,2-a]benzimidazol-2-yl)propanoate

CAS 844859-78-5C₂₁H₂₂N₄O₂

3-Methyl-1-pyrrolidin-1-ylpyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C17H16N4, CAS 305334-63-8

3-Methyl-1-pyrrolidin-1-ylpyrido[1,2-a]benzimidazole-4-carbonitrile

CAS 305334-63-8C₁₇H₁₆N₄

2-Ethyl-3-methyl-1-pyrrolidin-1-ylpyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C19H20N4, CAS 329708-65-8

2-Ethyl-3-methyl-1-pyrrolidin-1-ylpyrido[1,2-a]benzimidazole-4-carbonitrile

CAS 329708-65-8C₁₉H₂₀N₄

2-Isopropyl-3-methyl-1-(pyrrolidin-1-yl)benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile chemical structure, C20H22N4, CAS 371117-36-1

2-Isopropyl-3-methyl-1-(pyrrolidin-1-yl)benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile

CAS 371117-36-1C₂₀H₂₂N₄

2-Allyl-3-methyl-1-pyrrolidin-1-ylpyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C20H20N4, CAS 612037-61-3

2-Allyl-3-methyl-1-pyrrolidin-1-ylpyrido[1,2-a]benzimidazole-4-carbonitrile

CAS 612037-61-3C₂₀H₂₀N₄

3-(Propan-2-yl)-1-(pyrrolidin-1-yl)pyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C19H20N4, CAS 611197-80-9

3-(Propan-2-yl)-1-(pyrrolidin-1-yl)pyrido[1,2-a]benzimidazole-4-carbonitrile

CAS 611197-80-9C₁₉H₂₀N₄

3-Methyl-2-(2-methylprop-2-enyl)-1-pyrrolidin-1-ylpyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C21H22N4, CAS 612037-92-0

3-Methyl-2-(2-methylprop-2-enyl)-1-pyrrolidin-1-ylpyrido[1,2-a]benzimidazole-4-carbonitrile

CAS 612037-92-0C₂₁H₂₂N₄

3-Methyl-2-propyl-1-pyrrolidin-1-ylpyrido[1,2-a]benzimidazole-4-carbonitrile chemical structure, C20H22N4, CAS 849000-97-1

3-Methyl-2-propyl-1-pyrrolidin-1-ylpyrido[1,2-a]benzimidazole-4-carbonitrile

CAS 849000-97-1C₂₀H₂₂N₄