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Murcko scaffold

Ring system with 4 rings and 27 atoms

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
6
With full pages
2
Scaffold SMILES

c1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)ccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)ccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Canertinib dihydrochloride chemical structure, C24H27Cl3FN5O3, CAS 289499-45-2
Canertinib dihydrochloride
CAS 289499-45-2C24H27Cl3FN5O3
Canertinib chemical structure, C24H25ClFN5O3, CAS 267243-28-7
Canertinib
CAS 267243-28-7C24H25ClFN5O3
N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine chemical structure, C21H23ClFN5O2, CAS 267243-68-5
N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine
CAS 267243-68-5C21H23ClFN5O2
N4-(3-Bromo-4-fluorophenyl)-7-[3-(4-morpholinyl)propoxy]-4,6-quinazolinediamine chemical structure, C21H23BrFN5O2, CAS 267243-67-4
N4-(3-Bromo-4-fluorophenyl)-7-[3-(4-morpholinyl)propoxy]-4,6-quinazolinediamine
CAS 267243-67-4C21H23BrFN5O2
N-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)-6-nitroquinazolin-4-amine chemical structure, C21H21ClFN5O4, CAS 267243-64-1
N-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)-6-nitroquinazolin-4-amine
CAS 267243-64-1C21H21ClFN5O4
4-(3-Chloro-4-fluoroanilino)-6-methoxy-7-(3-morpholinopropoxy)quinazoline chemical structure, C22H24ClFN4O3, CAS 578737-96-9
4-(3-Chloro-4-fluoroanilino)-6-methoxy-7-(3-morpholinopropoxy)quinazoline
CAS 578737-96-9C22H24ClFN4O3