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Murcko scaffold

Ring system with 5 rings and 23 atoms

15 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
23
Chemicals
15
With full pages
1
Scaffold SMILES

O=C1NC2(c3ccccc3Oc3ccccc32)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC2(c3ccccc3Oc3ccccc32)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

2-Amino-3',6'-bis(dimethylamino)spiro[isoindole-3,9'-xanthene]-1-one chemical structure, C24H24N4O2, CAS 76918-79-1
2-Amino-3',6'-bis(dimethylamino)spiro[isoindole-3,9'-xanthene]-1-one
CAS 76918-79-1C24H24N4O2
Rhodamine B hydrazide chemical structure, C28H32N4O2, CAS 74317-53-6
Rhodamine B hydrazide
CAS 74317-53-6C28H32N4O2
N-Aminofluorescein chemical structure, C20H14N2O4, CAS 98907-26-7
N-Aminofluorescein
CAS 98907-26-7C20H14N2O4
N-hydroxy Rhodamine B amide chemical structure, C28H31N3O3, CAS 1115867-62-3
N-hydroxy Rhodamine B amide
CAS 1115867-62-3C28H31N3O3
Rhodamine 6G hydrazide chemical structure, C26H28N4O2, CAS 932013-08-6
Rhodamine 6G hydrazide
CAS 932013-08-6C26H28N4O2
2-(2-Aminoethyl)-3',6'-bis(diethylamino)spiro[isoindoline-1,9'-xanthen]-3-one chemical structure, C30H36N4O2, CAS 950846-89-6
2-(2-Aminoethyl)-3',6'-bis(diethylamino)spiro[isoindoline-1,9'-xanthen]-3-one
CAS 950846-89-6C30H36N4O2
2-(2-((2-Aminoethyl)amino)ethyl)-3',6'-bis(diethylamino)spiro[isoindoline-1,9'-xanthen]-3-one chemical structure, C32H41N5O2, CAS 1005459-81-3
2-(2-((2-Aminoethyl)amino)ethyl)-3',6'-bis(diethylamino)spiro[isoindoline-1,9'-xanthen]-3-one
CAS 1005459-81-3C32H41N5O2
3',6'-Bis(diethylamino)-2-methylspiro[isoindole-1,9'-xanthen]-3(2H)-one chemical structure, C29H33N3O2, CAS 80318-90-7
3',6'-Bis(diethylamino)-2-methylspiro[isoindole-1,9'-xanthen]-3(2H)-one
CAS 80318-90-7C29H33N3O2
3'-(Diethylamino)-6'-hydroxy-2-(2-hydroxyethyl)spiro[isoindoline-1,9'-xanthen]-3-one chemical structure, C26H26N2O4, CAS 1816281-76-1
3'-(Diethylamino)-6'-hydroxy-2-(2-hydroxyethyl)spiro[isoindoline-1,9'-xanthen]-3-one
CAS 1816281-76-1C26H26N2O4
2-Amino-3'-hydroxy-6'-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]spiro[isoindole-3,9'-xanthene]-1-one chemical structure, C26H26N2O7, CAS 1883737-63-0
2-Amino-3'-hydroxy-6'-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]spiro[isoindole-3,9'-xanthene]-1-one
CAS 1883737-63-0C26H26N2O7
2-Amino-5-bromo-3',6'-bis(diethylamino)-2,3-dihydrospiro[isoindole-1,9'-xanthene]-3-one chemical structure, C28H31BrN4O2, CAS 1394153-86-6
2-Amino-5-bromo-3',6'-bis(diethylamino)-2,3-dihydrospiro[isoindole-1,9'-xanthene]-3-one
CAS 1394153-86-6C28H31BrN4O2
2-(3'-((2-(Acryloyloxy)ethyl)(ethyl)amino)-6'-(ethylamino)-2',7'-dimethyl-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)ethyl acrylate chemical structure, C36H39N3O6, CAS 2097080-24-3
2-(3'-((2-(Acryloyloxy)ethyl)(ethyl)amino)-6'-(ethylamino)-2',7'-dimethyl-3-oxospiro[isoindoline-1,9'-xanthen]-2-yl)ethyl acrylate
CAS 2097080-24-3C36H39N3O6
2-[3',6'-Bis[ethyl(2-prop-2-enoyloxyethyl)amino]-2',7'-dimethyl-3-oxospiro[isoindole-1,9'-xanthene]-2-yl]ethyl prop-2-enoate chemical structure, C41H45N3O8, CAS 2097080-22-1
2-[3',6'-Bis[ethyl(2-prop-2-enoyloxyethyl)amino]-2',7'-dimethyl-3-oxospiro[isoindole-1,9'-xanthene]-2-yl]ethyl prop-2-enoate
CAS 2097080-22-1C41H45N3O8
3',6'-Bis(diethylamino)-2-[(E)-4-oxopentan-2-ylideneamino]spiro[isoindole-3,9'-xanthene]-1-one chemical structure, C33H38N4O3, CAS 1391913-90-8
3',6'-Bis(diethylamino)-2-[(E)-4-oxopentan-2-ylideneamino]spiro[isoindole-3,9'-xanthene]-1-one
CAS 1391913-90-8C33H38N4O3
Orb3211274 chemical structure, C29H34N6O3, CAS 2609717-46-4
Orb3211274
CAS 2609717-46-4C29H34N6O3