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Murcko scaffold

Ring system with 3 rings and 18 atoms

36 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
36
With full pages
10
Scaffold SMILES

O=C(Nc1ccccc1)C1CC1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)C1CC1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

2-Phenyl-N-[3-(trifluoromethyl)phenyl]cyclopropane-1-carboximidic acid chemical structure, C17H14F3NO, CAS 5278-65-9
2-Phenyl-N-[3-(trifluoromethyl)phenyl]cyclopropane-1-carboximidic acid
CAS 5278-65-9C17H14F3NO
N-(2,5-Dichlorophenyl)-2-phenylcyclopropanecarboxamide chemical structure, C16H13Cl2NO, CAS 5281-15-2
N-(2,5-Dichlorophenyl)-2-phenylcyclopropanecarboxamide
CAS 5281-15-2C16H13Cl2NO
(1R,2R)-N,2-Diphenylcyclopropane-1-carboxamide chemical structure, C16H15NO, CAS 79455-25-7
(1R,2R)-N,2-Diphenylcyclopropane-1-carboxamide
CAS 79455-25-7C16H15NO
N-(4-Methoxyphenyl)-2-phenylcyclopropanecarboxamide chemical structure, C17H17NO2, CAS 304445-95-2
N-(4-Methoxyphenyl)-2-phenylcyclopropanecarboxamide
CAS 304445-95-2C17H17NO2
N-(3-Nitrophenyl)-2-phenylcyclopropanecarboxamide chemical structure, C16H14N2O3, CAS 303768-92-5
N-(3-Nitrophenyl)-2-phenylcyclopropanecarboxamide
CAS 303768-92-5C16H14N2O3
N-(2,3-Dichlorophenyl)-2-phenylcyclopropanecarboxamide chemical structure, C16H13Cl2NO, CAS 550307-67-0
N-(2,3-Dichlorophenyl)-2-phenylcyclopropanecarboxamide
CAS 550307-67-0C16H13Cl2NO
N-(3-Chlorophenyl)-2-phenylcyclopropanecarboxamide chemical structure, C16H14ClNO, CAS 544681-65-4
N-(3-Chlorophenyl)-2-phenylcyclopropanecarboxamide
CAS 544681-65-4C16H14ClNO
2-Phenyl-N-[4-(propan-2-yl)phenyl]cyclopropanecarboxamide chemical structure, C19H21NO, CAS 438616-79-6
2-Phenyl-N-[4-(propan-2-yl)phenyl]cyclopropanecarboxamide
CAS 438616-79-6C19H21NO
N-(2-Ethylphenyl)-2-phenylcyclopropanecarboxamide chemical structure, C18H19NO, CAS 331274-68-1
N-(2-Ethylphenyl)-2-phenylcyclopropanecarboxamide
CAS 331274-68-1C18H19NO
2-Phenyl-N-[3-(trifluoromethyl)phenyl]cyclopropane-1-carboxamide chemical structure, C17H14F3NO, CAS 438529-39-6
2-Phenyl-N-[3-(trifluoromethyl)phenyl]cyclopropane-1-carboxamide
CAS 438529-39-6C17H14F3NO
2,2-Dichloro-N-(2,5-dimethylphenyl)-3-phenylcyclopropanecarboxamide chemical structure, C18H17Cl2NO, CAS 352643-07-3
2,2-Dichloro-N-(2,5-dimethylphenyl)-3-phenylcyclopropanecarboxamide
CAS 352643-07-3C18H17Cl2NO
2,2-Dichloro-N-(2-nitrophenyl)-3-phenylcyclopropane-1-carboxamide chemical structure, C16H12Cl2N2O3, CAS 328009-60-5
2,2-Dichloro-N-(2-nitrophenyl)-3-phenylcyclopropane-1-carboxamide
CAS 328009-60-5C16H12Cl2N2O3
N-(2,4-Dimethoxyphenyl)-2-phenylcyclopropanecarboxamide chemical structure, C18H19NO3, CAS 312525-02-3
N-(2,4-Dimethoxyphenyl)-2-phenylcyclopropanecarboxamide
CAS 312525-02-3C18H19NO3
N-(2-Methoxy-5-methylphenyl)-2-phenylcyclopropane-1-carboxamide chemical structure, C18H19NO2, CAS 353469-11-1
N-(2-Methoxy-5-methylphenyl)-2-phenylcyclopropane-1-carboxamide
CAS 353469-11-1C18H19NO2
Dimethyl 5-{[(2-phenylcyclopropyl)carbonyl]amino}isophthalate chemical structure, C20H19NO5, CAS 329042-89-9
Dimethyl 5-{[(2-phenylcyclopropyl)carbonyl]amino}isophthalate
CAS 329042-89-9C20H19NO5
2,2-Dichloro-N-(4-fluorophenyl)-3-phenylcyclopropanecarboxamide chemical structure, C16H12Cl2FNO, CAS 311787-98-1
2,2-Dichloro-N-(4-fluorophenyl)-3-phenylcyclopropanecarboxamide
CAS 311787-98-1C16H12Cl2FNO
2,2-Dichloro-N-(4-nitrophenyl)-3-phenylcyclopropane-1-carboxamide chemical structure, C16H12Cl2N2O3, CAS 306743-06-6
2,2-Dichloro-N-(4-nitrophenyl)-3-phenylcyclopropane-1-carboxamide
CAS 306743-06-6C16H12Cl2N2O3
2,2-Dichloro-N-(3-chloro-4-methylphenyl)-3-phenylcyclopropane-1-carboxamide chemical structure, C17H14Cl3NO, CAS 446050-10-8
2,2-Dichloro-N-(3-chloro-4-methylphenyl)-3-phenylcyclopropane-1-carboxamide
CAS 446050-10-8C17H14Cl3NO
N-(4-Ethoxy-2-nitrophenyl)-2-phenylcyclopropane-1-carboxamide chemical structure, C18H18N2O4, CAS 541524-56-5
N-(4-Ethoxy-2-nitrophenyl)-2-phenylcyclopropane-1-carboxamide
CAS 541524-56-5C18H18N2O4
N-(3-Acetylphenyl)-2-phenylcyclopropanecarboxamide chemical structure, C18H17NO2, CAS 339243-04-8
N-(3-Acetylphenyl)-2-phenylcyclopropanecarboxamide
CAS 339243-04-8C18H17NO2
N-(2-Ethoxyphenyl)-2-phenylcyclopropane-1-carboxamide chemical structure, C18H19NO2, CAS 545437-34-1
N-(2-Ethoxyphenyl)-2-phenylcyclopropane-1-carboxamide
CAS 545437-34-1C18H19NO2
N-(2-Fluorophenyl)-2-phenylcyclopropanecarboxamide chemical structure, C16H14FNO, CAS 541544-20-1
N-(2-Fluorophenyl)-2-phenylcyclopropanecarboxamide
CAS 541544-20-1C16H14FNO
Dimethyl 2-[(2-phenylcyclopropanecarbonyl)amino]benzene-1,4-dicarboxylate chemical structure, C20H19NO5, CAS 438453-68-0
Dimethyl 2-[(2-phenylcyclopropanecarbonyl)amino]benzene-1,4-dicarboxylate
CAS 438453-68-0C20H19NO5
N-(2,3-Dimethylphenyl)-2-phenylcyclopropanecarboxamide chemical structure, C18H19NO, CAS 545341-26-2
N-(2,3-Dimethylphenyl)-2-phenylcyclopropanecarboxamide
CAS 545341-26-2C18H19NO