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Murcko scaffold

Ring system with 3 rings and 26 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
11
With full pages
5
Scaffold SMILES

O=C(NCc1ccco1)C(=Cc1ccccc1)NC(=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1ccco1)C(=Cc1ccccc1)NC(=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

N-(1-(((2-Furylmethyl)amino)carbonyl)-2-(4-methylphenyl)vinyl)-4-methylbenzamide chemical structure, C23H22N2O3, CAS 307953-49-7
N-(1-(((2-Furylmethyl)amino)carbonyl)-2-(4-methylphenyl)vinyl)-4-methylbenzamide
CAS 307953-49-7C23H22N2O3
N-[(E)-3-(Furan-2-ylmethylamino)-1-(4-methylsulfanylphenyl)-3-oxoprop-1-en-2-yl]benzamide chemical structure, C22H20N2O3S, CAS 374908-23-3
N-[(E)-3-(Furan-2-ylmethylamino)-1-(4-methylsulfanylphenyl)-3-oxoprop-1-en-2-yl]benzamide
CAS 374908-23-3C22H20N2O3S
N-(1-{[(2-Furylmethyl)amino]carbonyl}-2-{4-nitrophenyl}vinyl)-4-methylbenzamide chemical structure, C22H19N3O5, CAS 314028-72-3
N-(1-{[(2-Furylmethyl)amino]carbonyl}-2-{4-nitrophenyl}vinyl)-4-methylbenzamide
CAS 314028-72-3C22H19N3O5
N-[(Z)-3-(Furan-2-ylmethylamino)-1-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]-3,4-dimethoxybenzamide chemical structure, C24H24N2O6, CAS 381201-06-5
N-[(Z)-3-(Furan-2-ylmethylamino)-1-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]-3,4-dimethoxybenzamide
CAS 381201-06-5C24H24N2O6
4-Acetylamino-N-{1-[(furan-2-ylmethyl)-carbamoyl]-2-phenyl-vinyl}-benzamide chemical structure, C23H21N3O4, CAS 428837-36-9
4-Acetylamino-N-{1-[(furan-2-ylmethyl)-carbamoyl]-2-phenyl-vinyl}-benzamide
CAS 428837-36-9C23H21N3O4
4-Chloro-N-(2-(3,4-dimethoxyphenyl)-1-{[(2-furylmethyl)amino]carbonyl}vinyl)benzamide chemical structure, C23H21ClN2O5, CAS 6241-13-0
4-Chloro-N-(2-(3,4-dimethoxyphenyl)-1-{[(2-furylmethyl)amino]carbonyl}vinyl)benzamide
CAS 6241-13-0C23H21ClN2O5
N-[(Z)-3-(Furan-2-ylmethylamino)-3-oxo-1-(4-propan-2-ylphenyl)prop-1-en-2-yl]benzamide chemical structure, C24H24N2O3, CAS 425630-40-6
N-[(Z)-3-(Furan-2-ylmethylamino)-3-oxo-1-(4-propan-2-ylphenyl)prop-1-en-2-yl]benzamide
CAS 425630-40-6C24H24N2O3
N-{2-(4-Fluoro-phenyl)-1-[(furan-2-ylmethyl)-carbamoyl]-vinyl}-benzamide chemical structure, C21H17FN2O3, CAS 373370-82-2
N-{2-(4-Fluoro-phenyl)-1-[(furan-2-ylmethyl)-carbamoyl]-vinyl}-benzamide
CAS 373370-82-2C21H17FN2O3
(E)-N-(1-(2-Fluorophenyl)-3-((furan-2-ylmethyl)amino)-3-oxoprop-1-en-2-yl)-4-methylbenzamide chemical structure, C22H19FN2O3, CAS 302822-79-3
(E)-N-(1-(2-Fluorophenyl)-3-((furan-2-ylmethyl)amino)-3-oxoprop-1-en-2-yl)-4-methylbenzamide
CAS 302822-79-3C22H19FN2O3
N-(1-{[(2-Furylmethyl)amino]carbonyl}-2-{4-nitrophenyl}vinyl)benzamide chemical structure, C21H17N3O5, CAS 303100-23-4
N-(1-{[(2-Furylmethyl)amino]carbonyl}-2-{4-nitrophenyl}vinyl)benzamide
CAS 303100-23-4C21H17N3O5
(Z)-N-(1-(4-Chlorophenyl)-3-((furan-2-ylmethyl)amino)-3-oxoprop-1-en-2-yl)-4-methylbenzamide chemical structure, C22H19ClN2O3, CAS 297145-62-1
(Z)-N-(1-(4-Chlorophenyl)-3-((furan-2-ylmethyl)amino)-3-oxoprop-1-en-2-yl)-4-methylbenzamide
CAS 297145-62-1C22H19ClN2O3