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Murcko scaffold

Ring system with 3 rings and 24 atoms

24 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
24
With full pages
3
Scaffold SMILES

O=C(Oc1ccccc1C(=O)C=Cc1cccs1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Oc1ccccc1C(=O)C=Cc1cccs1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

4-Fluoro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 4-methoxybenzoate chemical structure, C21H15FO4S, CAS 433245-76-2
4-Fluoro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 4-methoxybenzoate
CAS 433245-76-2C21H15FO4S
4-Fluoro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 2-methylbenzoate chemical structure, C21H15FO3S, CAS 433249-59-3
4-Fluoro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 2-methylbenzoate
CAS 433249-59-3C21H15FO3S
4-Chloro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 3-methoxybenzoate chemical structure, C21H15ClO4S, CAS 433249-73-1
4-Chloro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 3-methoxybenzoate
CAS 433249-73-1C21H15ClO4S
(E)-4-Fluoro-2-(3-(thiophen-2-yl)acryloyl)phenyl 3,4-dimethoxybenzoate chemical structure, C22H17FO5S, CAS 433251-35-5
(E)-4-Fluoro-2-(3-(thiophen-2-yl)acryloyl)phenyl 3,4-dimethoxybenzoate
CAS 433251-35-5C22H17FO5S
5-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 4-methoxybenzoate chemical structure, C22H18O5S, CAS 433252-28-9
5-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 4-methoxybenzoate
CAS 433252-28-9C22H18O5S
[5-Methoxy-2-[(E)-3-thiophen-2-ylprop-2-enoyl]phenyl] 2-bromobenzoate chemical structure, C21H15BrO4S, CAS 433255-75-5
[5-Methoxy-2-[(E)-3-thiophen-2-ylprop-2-enoyl]phenyl] 2-bromobenzoate
CAS 433255-75-5C21H15BrO4S
5-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 3-nitrobenzoate chemical structure, C21H15NO6S, CAS 1164461-62-4
5-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 3-nitrobenzoate
CAS 1164461-62-4C21H15NO6S
4-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 3-nitrobenzoate chemical structure, C21H15NO6S, CAS 1164454-45-8
4-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 3-nitrobenzoate
CAS 1164454-45-8C21H15NO6S
[4-Fluoro-2-[(E)-3-thiophen-2-ylprop-2-enoyl]phenyl] 4-bromobenzoate chemical structure, C20H12BrFO3S, CAS 433259-29-1
[4-Fluoro-2-[(E)-3-thiophen-2-ylprop-2-enoyl]phenyl] 4-bromobenzoate
CAS 433259-29-1C20H12BrFO3S
5-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 2-methoxybenzoate chemical structure, C22H18O5S, CAS 433259-58-6
5-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 2-methoxybenzoate
CAS 433259-58-6C22H18O5S
5-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 2-methylbenzoate chemical structure, C22H18O4S, CAS 433260-20-9
5-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 2-methylbenzoate
CAS 433260-20-9C22H18O4S
[4-Bromo-2-[(E)-3-thiophen-2-ylprop-2-enoyl]phenyl] 3-nitrobenzoate chemical structure, C20H12BrNO5S, CAS 433307-03-0
[4-Bromo-2-[(E)-3-thiophen-2-ylprop-2-enoyl]phenyl] 3-nitrobenzoate
CAS 433307-03-0C20H12BrNO5S
4-Bromo-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 2-methoxybenzoate chemical structure, C21H15BrO4S, CAS 433312-04-0
4-Bromo-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 2-methoxybenzoate
CAS 433312-04-0C21H15BrO4S
5-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 3-methoxybenzoate chemical structure, C22H18O5S, CAS 433312-34-6
5-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 3-methoxybenzoate
CAS 433312-34-6C22H18O5S
[4-Chloro-2-[(E)-3-thiophen-2-ylprop-2-enoyl]phenyl] 4-nitrobenzoate chemical structure, C20H12ClNO5S, CAS 433317-11-4
[4-Chloro-2-[(E)-3-thiophen-2-ylprop-2-enoyl]phenyl] 4-nitrobenzoate
CAS 433317-11-4C20H12ClNO5S
(E)-4-Fluoro-2-(3-(thiophen-2-yl)acryloyl)phenyl 3-nitrobenzoate chemical structure, C20H12FNO5S, CAS 1164454-19-6
(E)-4-Fluoro-2-(3-(thiophen-2-yl)acryloyl)phenyl 3-nitrobenzoate
CAS 1164454-19-6C20H12FNO5S
4-Chloro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 2-methoxybenzoate chemical structure, C21H15ClO4S, CAS 433320-02-6
4-Chloro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 2-methoxybenzoate
CAS 433320-02-6C21H15ClO4S
4-Fluoro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 2-bromobenzoate chemical structure, C20H12BrFO3S, CAS 433318-95-7
4-Fluoro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 2-bromobenzoate
CAS 433318-95-7C20H12BrFO3S
4-Fluoro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 4-nitrobenzoate chemical structure, C20H12FNO5S, CAS 433320-52-6
4-Fluoro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 4-nitrobenzoate
CAS 433320-52-6C20H12FNO5S
5-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 4-nitrobenzoate chemical structure, C21H15NO6S, CAS 433320-95-7
5-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 4-nitrobenzoate
CAS 433320-95-7C21H15NO6S
4-Fluoro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 2-methoxybenzoate chemical structure, C21H15FO4S, CAS 433324-21-1
4-Fluoro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl 2-methoxybenzoate
CAS 433324-21-1C21H15FO4S
[4-Bromo-2-[(E)-3-thiophen-2-ylprop-2-enoyl]phenyl] 4-nitrobenzoate chemical structure, C20H12BrNO5S, CAS 433325-47-4
[4-Bromo-2-[(E)-3-thiophen-2-ylprop-2-enoyl]phenyl] 4-nitrobenzoate
CAS 433325-47-4C20H12BrNO5S
4-Fluoro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl benzoate chemical structure, C20H13FO3S, CAS 637746-74-8
4-Fluoro-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl benzoate
CAS 637746-74-8C20H13FO3S
5-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl benzoate chemical structure, C21H16O4S, CAS 637746-73-7
5-Methoxy-2-[(2E)-3-(thiophen-2-yl)prop-2-enoyl]phenyl benzoate
CAS 637746-73-7C21H16O4S