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Murcko scaffold

Ring system with 3 rings and 23 atoms

33 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
33
With full pages
4
Scaffold SMILES

O=C(NCC1CN(Cc2ccccc2)CCO1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCC1CN(Cc2ccccc2)CCO1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

Mosapride citrate chemical structure, C27H33ClFN3O10, CAS 112885-42-4
Mosapride citrate
CAS 112885-42-4C27H33ClFN3O10
Mosapride chemical structure, C21H25ClFN3O3, CAS 112885-41-3
Mosapride
CAS 112885-41-3C21H25ClFN3O3
N-((4-Benzyl-2-morpholinyl)methyl)-5-chloro-4-(dimethylamino)-2-methoxybenzamide chemical structure, C22H28ClN3O3, CAS 112885-55-9
N-((4-Benzyl-2-morpholinyl)methyl)-5-chloro-4-(dimethylamino)-2-methoxybenzamide
CAS 112885-55-9C22H28ClN3O3
4-Amino-N-((4-benzyl-2-morpholinyl)methyl)-5-chloro-2-methoxybenzamide chemical structure, C20H24ClN3O3, CAS 112885-23-1
4-Amino-N-((4-benzyl-2-morpholinyl)methyl)-5-chloro-2-methoxybenzamide
CAS 112885-23-1C20H24ClN3O3
4-Amino-N-((4-benzyl-2-morpholinyl)-methyl)-5-chloro-2-ethoxybenzamide chemical structure, C21H26ClN3O3, CAS 112885-33-3
4-Amino-N-((4-benzyl-2-morpholinyl)-methyl)-5-chloro-2-ethoxybenzamide
CAS 112885-33-3C21H26ClN3O3
Benzamide, 4-amino-5-chloro-2-ethoxy-N-((4-((4-fluorophenyl)methyl)-2-morpholinyl)methyl)-, hydrochloride, dihydrate chemical structure, C21H26Cl2FN3O3, CAS 131322-37-7
Benzamide, 4-amino-5-chloro-2-ethoxy-N-((4-((4-fluorophenyl)methyl)-2-morpholinyl)methyl)-, hydrochloride, dihydrate
CAS 131322-37-7C21H26Cl2FN3O3
Benzamide, 4-amino-5-chloro-N-((4-((3-cyanophenyl)methyl)-2-morpholinyl)methyl)-2-methoxy-, ethanedioate, hydrate (1:1:1) chemical structure, C23H25ClN4O7, CAS 112885-00-4
Benzamide, 4-amino-5-chloro-N-((4-((3-cyanophenyl)methyl)-2-morpholinyl)methyl)-2-methoxy-, ethanedioate, hydrate (1:1:1)
CAS 112885-00-4C23H25ClN4O7
Benzamide, 4-amino-5-chloro-N-((4-((2-cyanophenyl)methyl)-2-morpholinyl)methyl)-2-methoxy- chemical structure, C21H23ClN4O3, CAS 112885-01-5
Benzamide, 4-amino-5-chloro-N-((4-((2-cyanophenyl)methyl)-2-morpholinyl)methyl)-2-methoxy-
CAS 112885-01-5C21H23ClN4O3
Benzamide, 4-amino-5-chloro-2-methoxy-N-((4-((pentafluorophenyl)methyl)-2-morpholinyl)methyl)- chemical structure, C20H19ClF5N3O3, CAS 112885-12-8
Benzamide, 4-amino-5-chloro-2-methoxy-N-((4-((pentafluorophenyl)methyl)-2-morpholinyl)methyl)-
CAS 112885-12-8C20H19ClF5N3O3
Benzamide, 4-amino-5-chloro-2-ethoxy-N-((4-(1-phenylethyl)-2-morpholinyl)methyl)-, ethanedioate, hydrate (1:1:1) chemical structure, C24H30ClN3O7, CAS 112886-39-2
Benzamide, 4-amino-5-chloro-2-ethoxy-N-((4-(1-phenylethyl)-2-morpholinyl)methyl)-, ethanedioate, hydrate (1:1:1)
CAS 112886-39-2C24H30ClN3O7
Benzamide, 4-amino-5-chloro-N-((4-((4-cyanophenyl)methyl)-2-morpholinyl)methyl)-2-ethoxy- chemical structure, C22H25ClN4O3, CAS 112886-47-2
Benzamide, 4-amino-5-chloro-N-((4-((4-cyanophenyl)methyl)-2-morpholinyl)methyl)-2-ethoxy-
CAS 112886-47-2C22H25ClN4O3
Benzamide, 4-amino-5-chloro-2-ethoxy-N-((4-((3-(trifluoromethyl)phenyl)methyl)-2-morpholinyl)methyl)- chemical structure, C22H25ClF3N3O3, CAS 112886-49-4
Benzamide, 4-amino-5-chloro-2-ethoxy-N-((4-((3-(trifluoromethyl)phenyl)methyl)-2-morpholinyl)methyl)-
CAS 112886-49-4C22H25ClF3N3O3
Benzamide, 4-amino-5-chloro-N-((4-((4-chlorophenyl)methyl)-2-morpholinyl)methyl)-2-ethoxy- chemical structure, C21H25Cl2N3O3, CAS 112886-52-9
Benzamide, 4-amino-5-chloro-N-((4-((4-chlorophenyl)methyl)-2-morpholinyl)methyl)-2-ethoxy-
CAS 112886-52-9C21H25Cl2N3O3
Benzamide, 4-amino-5-chloro-N-((4-((3-chlorophenyl)methyl)-2-morpholinyl)methyl)-2-ethoxy-, hydrochloride, hydrate (2:2:1) chemical structure, C21H26Cl3N3O3, CAS 112886-53-0
Benzamide, 4-amino-5-chloro-N-((4-((3-chlorophenyl)methyl)-2-morpholinyl)methyl)-2-ethoxy-, hydrochloride, hydrate (2:2:1)
CAS 112886-53-0C21H26Cl3N3O3
Benzamide, 4-amino-5-chloro-N-((4-((2-chlorophenyl)methyl)-2-morpholinyl)methyl)-2-ethoxy-, hydrochloride, hydrate (2:2:1) chemical structure, C21H26Cl3N3O3, CAS 112886-54-1
Benzamide, 4-amino-5-chloro-N-((4-((2-chlorophenyl)methyl)-2-morpholinyl)methyl)-2-ethoxy-, hydrochloride, hydrate (2:2:1)
CAS 112886-54-1C21H26Cl3N3O3
Benzamide, 4-amino-5-chloro-N-((4-((4-chlorophenyl)methyl)-2-morpholinyl)methyl)-2-methoxy-, (E)-2-butenedioate (1:2) chemical structure, C28H31Cl2N3O11, CAS 131322-36-6
Benzamide, 4-amino-5-chloro-N-((4-((4-chlorophenyl)methyl)-2-morpholinyl)methyl)-2-methoxy-, (E)-2-butenedioate (1:2)
CAS 131322-36-6C28H31Cl2N3O11
Benzamide, 4-amino-5-chloro-2-methoxy-N-((4-(1-phenylethyl)-2-morpholinyl)methyl)-, (E)-2-butenedioate, hydrate (2:2:1) chemical structure, C25H30ClN3O7, CAS 112884-95-4
Benzamide, 4-amino-5-chloro-2-methoxy-N-((4-(1-phenylethyl)-2-morpholinyl)methyl)-, (E)-2-butenedioate, hydrate (2:2:1)
CAS 112884-95-4C25H30ClN3O7
Benzamide, 4-amino-5-chloro-2-methoxy-N-((4-((3-(trifluoromethyl)phenyl)methyl)-2-morpholinyl)methyl)-, (E)-2-butenedioate, hydrate (2:3:1) chemical structure, C54H58Cl2F6N6O18, CAS 112885-08-2
Benzamide, 4-amino-5-chloro-2-methoxy-N-((4-((3-(trifluoromethyl)phenyl)methyl)-2-morpholinyl)methyl)-, (E)-2-butenedioate, hydrate (2:3:1)
CAS 112885-08-2C54H58Cl2F6N6O18
Benzamide, 4-amino-5-chloro-N-((4-((4-cyanophenyl)methyl)-2-morpholinyl)methyl)-2-methoxy-, (E)-2-butenedioate (1:1) chemical structure, C25H27ClN4O7, CAS 112885-35-5
Benzamide, 4-amino-5-chloro-N-((4-((4-cyanophenyl)methyl)-2-morpholinyl)methyl)-2-methoxy-, (E)-2-butenedioate (1:1)
CAS 112885-35-5C25H27ClN4O7
Mosapride citrate dihydrate chemical structure, C27H37ClFN3O12, CAS 636582-62-2
Mosapride citrate dihydrate
CAS 636582-62-2C27H37ClFN3O12
Afj1SD6knr chemical structure, C21H25ClFN3O3, CAS 156925-23-4
Afj1SD6knr
CAS 156925-23-4C21H25ClFN3O3
Mosapride, (R)- chemical structure, C21H25ClFN3O3, CAS 156925-24-5
Mosapride, (R)-
CAS 156925-24-5C21H25ClFN3O3
2-Amino-N-[(4-benzylmorpholin-2-yl)methyl]-5-nitrobenzamide chemical structure, C19H22N4O4, CAS 112887-15-7
2-Amino-N-[(4-benzylmorpholin-2-yl)methyl]-5-nitrobenzamide
CAS 112887-15-7C19H22N4O4
Benzamide, 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-, (R)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) chemical structure, C27H33ClFN3O10, CAS 156925-26-7
Benzamide, 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-, (R)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
CAS 156925-26-7C27H33ClFN3O10