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Murcko scaffold

Ring system with 5 rings and 32 atoms

5 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
32
Chemicals
5
With full pages
1
Scaffold SMILES

c1ccc(C(c2ccccc2)N2CCN(CCCOc3cccc4[nH]ccc34)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C(c2ccccc2)N2CCN(CCCOc3cccc4[nH]ccc34)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

4-(3-(4-(Diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile chemical structure, C29H30N4O2, CAS 97730-95-5
4-(3-(4-(Diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
CAS 97730-95-5C29H30N4O2
Bdf 9145 chemical structure, C31H31N5O3, CAS 130320-49-9
Bdf 9145
CAS 130320-49-9C31H31N5O3
4-((2S)-3-(4-(Diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile chemical structure, C29H30N4O2, CAS 97749-21-8
4-((2S)-3-(4-(Diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile
CAS 97749-21-8C29H30N4O2
1H-Indole-2-carbonitrile, 4-((2R)-3-(4-(diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)- chemical structure, C29H30N4O2, CAS 97749-20-7
1H-Indole-2-carbonitrile, 4-((2R)-3-(4-(diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-
CAS 97749-20-7C29H30N4O2
4-(3-(4-(Diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile bismesylate chemical structure, C31H38N4O8S2, CAS 78573-15-6
4-(3-(4-(Diphenylmethyl)-1-piperazinyl)-2-hydroxypropoxy)-1H-indole-2-carbonitrile bismesylate
CAS 78573-15-6C31H38N4O8S2