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Murcko scaffold

Ring system with 4 rings and 31 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
31
Chemicals
10
With full pages
4
Scaffold SMILES

O=C(c1ccc(CNS(=O)(=O)c2ccccc2)cc1)N1CCN(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccc(CNS(=O)(=O)c2ccccc2)cc1)N1CCN(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

4-(tert-Butyl)-N-(4-(4-phenylpiperazine-1-carbonyl)benzyl)benzenesulfonamide chemical structure, C28H33N3O3S, CAS 690644-14-5
4-(tert-Butyl)-N-(4-(4-phenylpiperazine-1-carbonyl)benzyl)benzenesulfonamide
CAS 690644-14-5C28H33N3O3S
2,5-Dimethyl-N-{4-[(4-phenyl-1-piperazinyl)carbonyl]benzyl}benzenesulfonamide chemical structure, C26H29N3O3S, CAS 690245-74-0
2,5-Dimethyl-N-{4-[(4-phenyl-1-piperazinyl)carbonyl]benzyl}benzenesulfonamide
CAS 690245-74-0C26H29N3O3S
N-(4-(4-(2-Fluorophenyl)piperazine-1-carbonyl)benzyl)-2,5-dimethylbenzenesulfonamide chemical structure, C26H28FN3O3S, CAS 690245-75-1
N-(4-(4-(2-Fluorophenyl)piperazine-1-carbonyl)benzyl)-2,5-dimethylbenzenesulfonamide
CAS 690245-75-1C26H28FN3O3S
3-Methoxy-N-(4-(4-phenylpiperazine-1-carbonyl)benzyl)benzenesulfonamide chemical structure, C25H27N3O4S, CAS 690245-63-7
3-Methoxy-N-(4-(4-phenylpiperazine-1-carbonyl)benzyl)benzenesulfonamide
CAS 690245-63-7C25H27N3O4S
N-[[4-[4-(2-Fluorophenyl)piperazine-1-carbonyl]phenyl]methyl]-3-methoxybenzenesulfonamide chemical structure, C25H26FN3O4S, CAS 690245-64-8
N-[[4-[4-(2-Fluorophenyl)piperazine-1-carbonyl]phenyl]methyl]-3-methoxybenzenesulfonamide
CAS 690245-64-8C25H26FN3O4S
3-Methoxy-N-(4-{[4-(2-methoxyphenyl)-1-piperazinyl]carbonyl}benzyl)benzenesulfonamide chemical structure, C26H29N3O5S, CAS 690643-92-6
3-Methoxy-N-(4-{[4-(2-methoxyphenyl)-1-piperazinyl]carbonyl}benzyl)benzenesulfonamide
CAS 690643-92-6C26H29N3O5S
3-Chloro-N-(4-(4-(2-fluorophenyl)piperazine-1-carbonyl)benzyl)benzenesulfonamide chemical structure, C24H23ClFN3O3S, CAS 690245-50-2
3-Chloro-N-(4-(4-(2-fluorophenyl)piperazine-1-carbonyl)benzyl)benzenesulfonamide
CAS 690245-50-2C24H23ClFN3O3S
4-(tert-Butyl)-N-(4-(4-(4-methoxyphenyl)piperazine-1-carbonyl)benzyl)benzenesulfonamide chemical structure, C29H35N3O4S, CAS 727689-24-9
4-(tert-Butyl)-N-(4-(4-(4-methoxyphenyl)piperazine-1-carbonyl)benzyl)benzenesulfonamide
CAS 727689-24-9C29H35N3O4S
N-(4-(4-(4-Methoxyphenyl)piperazine-1-carbonyl)benzyl)-2,5-dimethylbenzenesulfonamide chemical structure, C27H31N3O4S, CAS 690644-03-2
N-(4-(4-(4-Methoxyphenyl)piperazine-1-carbonyl)benzyl)-2,5-dimethylbenzenesulfonamide
CAS 690644-03-2C27H31N3O4S
4-Fluoro-N-{4-[(4-phenylpiperazin-1-yl)carbonyl]benzyl}benzenesulfonamide chemical structure, C24H24FN3O3S, CAS 1010921-04-6
4-Fluoro-N-{4-[(4-phenylpiperazin-1-yl)carbonyl]benzyl}benzenesulfonamide
CAS 1010921-04-6C24H24FN3O3S