Murcko scaffold
Ring system with 4 rings and 27 atoms
24 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 27
- Chemicals
- 24
- With full pages
- 1
Scaffold SMILES
O=C(Nc1cccc(-c2ccc(N3CCNCC3)nn2)c1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 24 of 24 chemicals
2-Methyl-N-(3-(6-(4-methylpiperazin-1-yl)pyridazin-3-yl)phenyl)benzamide
CAS 899970-07-1C23H25N5O
![4-Methyl-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide chemical structure, C23H25N5O, CAS 899758-85-1](/s/WXZBAAWALIBADK-UHFFFAOYSA-N.svg)
4-Methyl-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide
CAS 899758-85-1C23H25N5O
3-Methoxy-N-(3-(6-(4-methylpiperazin-1-yl)pyridazin-3-yl)phenyl)benzamide
CAS 899970-10-6C23H25N5O2
4-Methoxy-N-(3-(6-(4-methylpiperazin-1-yl)pyridazin-3-yl)phenyl)benzamide
CAS 899758-88-4C23H25N5O2
N-(3-(6-(4-Methylpiperazin-1-yl)pyridazin-3-yl)phenyl)-2-nitrobenzamide
CAS 899980-87-1C22H22N6O3
N-(3-(6-(4-Methylpiperazin-1-yl)pyridazin-3-yl)phenyl)-3-nitrobenzamide
CAS 899970-16-2C22H22N6O3
![3,4-Difluoro-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide chemical structure, C22H21F2N5O, CAS 899980-91-7](/s/XTCPOFXGJJYBMA-UHFFFAOYSA-N.svg)
3,4-Difluoro-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide
CAS 899980-91-7C22H21F2N5O
![2-Chloro-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide chemical structure, C22H22ClN5O, CAS 899970-22-0](/s/XYACTSZTWBSZOB-UHFFFAOYSA-N.svg)
2-Chloro-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide
CAS 899970-22-0C22H22ClN5O
4-Chloro-N-(3-(6-(4-methylpiperazin-1-yl)pyridazin-3-yl)phenyl)benzamide
CAS 899759-00-3C22H22ClN5O
![4-Ethoxy-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide chemical structure, C24H27N5O2, CAS 899970-30-0](/s/WVHSXVKSNBKHKL-UHFFFAOYSA-N.svg)
4-Ethoxy-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide
CAS 899970-30-0C24H27N5O2
![3-Methyl-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide chemical structure, C23H25N5O, CAS 899981-04-5](/s/PWDXBKYCZKCKGM-UHFFFAOYSA-N.svg)
3-Methyl-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide
CAS 899981-04-5C23H25N5O
![3,5-Dimethyl-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide chemical structure, C24H27N5O, CAS 899759-10-5](/s/ZBVZXYCKPLKSGL-UHFFFAOYSA-N.svg)
3,5-Dimethyl-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide
CAS 899759-10-5C24H27N5O
![2-Ethoxy-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide chemical structure, C24H27N5O2, CAS 899970-32-2](/s/VQDVXUDEXQYMMG-UHFFFAOYSA-N.svg)
2-Ethoxy-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide
CAS 899970-32-2C24H27N5O2
![2,4-Difluoro-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide chemical structure, C22H21F2N5O, CAS 899970-34-4](/s/NQYQMYWWHJODBJ-UHFFFAOYSA-N.svg)
2,4-Difluoro-N-[3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl]benzamide
CAS 899970-34-4C22H21F2N5O
N-(3-(6-(4-Methylpiperazin-1-yl)pyridazin-3-yl)phenyl)-4-nitrobenzamide
CAS 899759-06-9C22H22N6O3
![2,6-Dimethoxy-N-{3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl}benzamide chemical structure, C24H27N5O3, CAS 922634-81-9](/s/KPJLGXXKGWSFMZ-UHFFFAOYSA-N.svg)
2,6-Dimethoxy-N-{3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl}benzamide
CAS 922634-81-9C24H27N5O3
![2-Methyl-N-{3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl}-3-nitrobenzamide chemical structure, C23H24N6O3, CAS 899980-98-4](/s/KISOBFBTUANYCM-UHFFFAOYSA-N.svg)
2-Methyl-N-{3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl}-3-nitrobenzamide
CAS 899980-98-4C23H24N6O3
4-Methyl-N-(3-(6-(4-methylpiperazin-1-yl)pyridazin-3-yl)phenyl)-3-nitrobenzamide
CAS 899980-83-7C23H24N6O3
![N-{3-[6-(4-Methylpiperazin-1-yl)pyridazin-3-yl]phenyl}-4-(trifluoromethyl)benzamide chemical structure, C23H22F3N5O, CAS 922561-09-9](/s/VBVDRKJQHNCAJD-UHFFFAOYSA-N.svg)
N-{3-[6-(4-Methylpiperazin-1-yl)pyridazin-3-yl]phenyl}-4-(trifluoromethyl)benzamide
CAS 922561-09-9C23H22F3N5O
![N-{3-[6-(4-Methylpiperazin-1-yl)pyridazin-3-yl]phenyl}-3-(trifluoromethyl)benzamide chemical structure, C23H22F3N5O, CAS 922808-83-1](/s/UISJROFCGNFXJH-UHFFFAOYSA-N.svg)
N-{3-[6-(4-Methylpiperazin-1-yl)pyridazin-3-yl]phenyl}-3-(trifluoromethyl)benzamide
CAS 922808-83-1C23H22F3N5O
![2-Chloro-6-fluoro-N-{3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl}benzamide chemical structure, C22H21ClFN5O, CAS 922808-86-4](/s/ACZCDJKTGACQQR-UHFFFAOYSA-N.svg)
2-Chloro-6-fluoro-N-{3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl}benzamide
CAS 922808-86-4C22H21ClFN5O
3-Methyl-N-(3-(6-(4-methylpiperazin-1-yl)pyridazin-3-yl)phenyl)-4-nitrobenzamide
CAS 899981-10-3C23H24N6O3
![2,4-Dichloro-N-{3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl}benzamide chemical structure, C22H21Cl2N5O, CAS 922561-24-8](/s/OLQNNSIOMHPYKR-UHFFFAOYSA-N.svg)
2,4-Dichloro-N-{3-[6-(4-methylpiperazin-1-yl)pyridazin-3-yl]phenyl}benzamide
CAS 922561-24-8C22H21Cl2N5O
2,5-Dichloro-N-(3-(6-(4-methylpiperazin-1-yl)pyridazin-3-yl)phenyl)benzamide
CAS 922808-98-8C22H21Cl2N5O
Related scaffolds
Same ring framework with different atoms or bond orders
