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Murcko scaffold

Ring system with 4 rings and 26 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
10
With full pages
8
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc(-c2n[nH]c(=O)c3ccccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccc(-c2n[nH]c(=O)c3ccccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-[4-[2-(Methylamino)-2-oxoethoxy]phenyl]-4-(3-methyl-4-oxophthalazin-1-yl)benzamide chemical structure, C25H22N4O4, CAS 701229-53-0
N-[4-[2-(Methylamino)-2-oxoethoxy]phenyl]-4-(3-methyl-4-oxophthalazin-1-yl)benzamide
CAS 701229-53-0C25H22N4O4
N-(2-Methoxyphenyl)-4-(3-methyl-4-oxophthalazin-1-yl)benzamide chemical structure, C23H19N3O3, CAS 701223-60-1
N-(2-Methoxyphenyl)-4-(3-methyl-4-oxophthalazin-1-yl)benzamide
CAS 701223-60-1C23H19N3O3
N-(2,4-Dimethylphenyl)-4-(3-methyl-4-oxophthalazin-1-yl)benzamide chemical structure, C24H21N3O2, CAS 701230-13-9
N-(2,4-Dimethylphenyl)-4-(3-methyl-4-oxophthalazin-1-yl)benzamide
CAS 701230-13-9C24H21N3O2
N-(3-Chlorophenyl)-4-(3-methyl-4-oxophthalazin-1-yl)benzamide chemical structure, C22H16ClN3O2, CAS 701231-02-9
N-(3-Chlorophenyl)-4-(3-methyl-4-oxophthalazin-1-yl)benzamide
CAS 701231-02-9C22H16ClN3O2
2-Methoxy-5-[[4-(3-methyl-4-oxophthalazin-1-yl)benzoyl]amino]benzamide chemical structure, C24H20N4O4, CAS 702646-66-0
2-Methoxy-5-[[4-(3-methyl-4-oxophthalazin-1-yl)benzoyl]amino]benzamide
CAS 702646-66-0C24H20N4O4
4-(3-Methyl-4-oxophthalazin-1-yl)-N-[3-(trifluoromethyl)phenyl]benzamide chemical structure, C23H16F3N3O2, CAS 696635-15-1
4-(3-Methyl-4-oxophthalazin-1-yl)-N-[3-(trifluoromethyl)phenyl]benzamide
CAS 696635-15-1C23H16F3N3O2
4-(3-Methyl-4-oxo-3,4-dihydrophthalazin-1-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide chemical structure, C23H16F3N3O3, CAS 696634-58-9
4-(3-Methyl-4-oxo-3,4-dihydrophthalazin-1-yl)-N-[4-(trifluoromethoxy)phenyl]benzamide
CAS 696634-58-9C23H16F3N3O3
N-(4-Fluorophenyl)-4-(3-methyl-4-oxophthalazin-1-yl)benzamide chemical structure, C22H16FN3O2, CAS 701240-08-6
N-(4-Fluorophenyl)-4-(3-methyl-4-oxophthalazin-1-yl)benzamide
CAS 701240-08-6C22H16FN3O2
N-[4-(Diethylcarbamoyl)phenyl]-4-(3-methyl-4-oxophthalazin-1-yl)benzamide chemical structure, C27H26N4O3, CAS 701238-49-5
N-[4-(Diethylcarbamoyl)phenyl]-4-(3-methyl-4-oxophthalazin-1-yl)benzamide
CAS 701238-49-5C27H26N4O3
4-(3-Methyl-4-oxophthalazin-1-yl)-N-(4-methylphenyl)benzamide chemical structure, C23H19N3O2, CAS 701241-96-5
4-(3-Methyl-4-oxophthalazin-1-yl)-N-(4-methylphenyl)benzamide
CAS 701241-96-5C23H19N3O2