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Murcko scaffold

2-(1H-Indol-3-yl)-2-oxo-N-(5-oxo-1-phenylpyrrolidin-3-yl)acetamide scaffold

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
10
With full pages
7
Scaffold SMILES

O=C(NC1CC(=O)N(c2ccccc2)C1)C(=O)c1c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1H-Indol-3-yl)-2-oxo-N-(5-oxo-1-phenylpyrrolidin-3-yl)acetamide page
Murcko scaffold O=C(NC1CC(=O)N(c2ccccc2)C1)C(=O)c1c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

2-(2-Methyl-1H-indol-3-yl)-2-oxo-N-(5-oxo-1-phenylpyrrolidin-3-yl)acetamide chemical structure, C21H19N3O3, CAS 896363-32-9
2-(2-Methyl-1H-indol-3-yl)-2-oxo-N-(5-oxo-1-phenylpyrrolidin-3-yl)acetamide
CAS 896363-32-9C21H19N3O3
N-[1-(3-Methoxyphenyl)-5-oxopyrrolidin-3-yl]-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide chemical structure, C22H21N3O4, CAS 896274-43-4
N-[1-(3-Methoxyphenyl)-5-oxopyrrolidin-3-yl]-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide
CAS 896274-43-4C22H21N3O4
2-(1H-Indol-3-yl)-2-oxo-N-(5-oxo-1-phenylpyrrolidin-3-yl)acetamide chemical structure, C20H17N3O3, CAS 896363-27-2
2-(1H-Indol-3-yl)-2-oxo-N-(5-oxo-1-phenylpyrrolidin-3-yl)acetamide
CAS 896363-27-2C20H17N3O3
2-(2-Methyl-1H-indol-3-yl)-N-[1-(4-methylphenyl)-5-oxopyrrolidin-3-yl]-2-oxoacetamide chemical structure, C22H21N3O3, CAS 896368-06-2
2-(2-Methyl-1H-indol-3-yl)-N-[1-(4-methylphenyl)-5-oxopyrrolidin-3-yl]-2-oxoacetamide
CAS 896368-06-2C22H21N3O3
N-(1-(3,4-Dimethylphenyl)-5-oxopyrrolidin-3-yl)-2-(1H-indol-3-yl)-2-oxoacetamide chemical structure, C22H21N3O3, CAS 896371-72-5
N-(1-(3,4-Dimethylphenyl)-5-oxopyrrolidin-3-yl)-2-(1H-indol-3-yl)-2-oxoacetamide
CAS 896371-72-5C22H21N3O3
N-[1-(3,4-Dimethylphenyl)-5-oxopyrrolidin-3-yl]-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide chemical structure, C23H23N3O3, CAS 896371-77-0
N-[1-(3,4-Dimethylphenyl)-5-oxopyrrolidin-3-yl]-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide
CAS 896371-77-0C23H23N3O3
2-(1H-Indol-3-yl)-N-[1-(3-methoxyphenyl)-5-oxopyrrolidin-3-yl]-2-oxoacetamide chemical structure, C21H19N3O4, CAS 896274-35-4
2-(1H-Indol-3-yl)-N-[1-(3-methoxyphenyl)-5-oxopyrrolidin-3-yl]-2-oxoacetamide
CAS 896274-35-4C21H19N3O4
N-[1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl]-2-(1H-indol-3-yl)-2-oxoacetamide chemical structure, C20H16FN3O3, CAS 896291-52-4
N-[1-(3-Fluorophenyl)-5-oxopyrrolidin-3-yl]-2-(1H-indol-3-yl)-2-oxoacetamide
CAS 896291-52-4C20H16FN3O3
N-[1-(4-Fluorophenyl)-5-oxopyrrolidin-3-yl]-2-(1H-indol-3-yl)-2-oxoacetamide chemical structure, C20H16FN3O3, CAS 896297-02-2
N-[1-(4-Fluorophenyl)-5-oxopyrrolidin-3-yl]-2-(1H-indol-3-yl)-2-oxoacetamide
CAS 896297-02-2C20H16FN3O3
N-[1-(4-Fluorophenyl)-5-oxopyrrolidin-3-yl]-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide chemical structure, C21H18FN3O3, CAS 896297-10-2
N-[1-(4-Fluorophenyl)-5-oxopyrrolidin-3-yl]-2-(2-methyl-1H-indol-3-yl)-2-oxoacetamide
CAS 896297-10-2C21H18FN3O3