Murcko scaffold
Ring system with 6 rings and 26 atoms
21 chemicals on CompoundList share this ring system.
- Rings
- 6
- Scaffold atoms
- 26
- Chemicals
- 21
- With full pages
- 2
Scaffold SMILES
O=C1Cc2cc3n(c(=O)c2CO1)Cc1cc2cc4c(cc2nc1-3)OCO4
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 21 of 21 chemicals
10,11-Methylenedioxy-20-camptothecin
CAS 104155-89-7C21H16N2O6
7-Ethyl-10,11-methylenedioxy-20-S-camptothecin
CAS 169900-78-1C23H20N2O6
7-Chloromethyl-10,11-methylenedioxycamptothecin
CAS 149882-14-4C22H17ClN2O6
10H-1,3-Dioxolo(4,5-g)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-8,11(7H,13H)-dione, 7-ethyl-7-hydroxy-14-methyl-, (7S)-
CAS 172546-50-8C22H18N2O6
(R)-FL118
CAS 151636-76-9C21H16N2O6
![5-Ethyl-5-hydroxy-16-nitro-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.04,9.015,23.017,21]tetracosa-1(24),2,4(9),13,15,17(21),22-heptaene-6,10-dione chemical structure, C21H15N3O8, CAS 135095-69-1](/s/DMUCLZLYDBNSRL-UHFFFAOYSA-N.svg)
5-Ethyl-5-hydroxy-16-nitro-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.04,9.015,23.017,21]tetracosa-1(24),2,4(9),13,15,17(21),22-heptaene-6,10-dione
CAS 135095-69-1C21H15N3O8
![7-Ethyl-7-hydroxy-14-[2-(propylamino)ethyl]-10H-1,3-dioxolo[4,5-g]pyrano[3a(2),4a(2):6,7]indolizino[1,2-b]quinoline-8,11(7H,13H)-dione chemical structure, C26H27N3O6, CAS 256411-96-8](/s/CYGHPPAJLHDGDT-UHFFFAOYSA-N.svg)
7-Ethyl-7-hydroxy-14-[2-(propylamino)ethyl]-10H-1,3-dioxolo[4,5-g]pyrano[3a(2),4a(2):6,7]indolizino[1,2-b]quinoline-8,11(7H,13H)-dione
CAS 256411-96-8C26H27N3O6
7-Hydroxymethyl-10,11-MDCPT
CAS 428816-69-7C22H18N2O7
![(7S)-7-Ethyl-7-hydroxy-2-(hydroxymethyl)-10H-1,3-dioxolo[4,5-g]pyrano[3a(2),4a(2):6,7]indolizino[1,2-b]quinoline-8,11(7H,13H)-dione chemical structure, C22H18N2O7, CAS 208578-62-5](/s/XSJAHUBJVVHHKK-YSYXNDDBSA-N.svg)
(7S)-7-Ethyl-7-hydroxy-2-(hydroxymethyl)-10H-1,3-dioxolo[4,5-g]pyrano[3a(2),4a(2):6,7]indolizino[1,2-b]quinoline-8,11(7H,13H)-dione
CAS 208578-62-5C22H18N2O7
7-Mad-mdcpt
CAS 765871-81-6C22H19N3O6
Gly-7-MAD-MDCPT
CAS 2378427-68-8C24H22N4O7
FL118-14-Propanol
CAS 2821768-98-1C24H22N2O7
FL118-C3-O-C-amide-C-NH2
CAS 2821769-41-7C27H28N4O8
![(S)-14-(Aminomethyl)-7-ethyl-7-hydroxy-10,13-dihydro-11H-[1,3]dioxolo[4,5-g]pyrano[3 inverted exclamation mark,4 inverted exclamation mark:6,7]indolizino[1,2-b]quinoline-8,11(7H)-dione-2,2-d2 chemical structure, C22H19N3O6, CAS 2839561-37-2](/s/QILNNZJGRYNYJV-GFIFTMAESA-N.svg)
(S)-14-(Aminomethyl)-7-ethyl-7-hydroxy-10,13-dihydro-11H-[1,3]dioxolo[4,5-g]pyrano[3 inverted exclamation mark,4 inverted exclamation mark:6,7]indolizino[1,2-b]quinoline-8,11(7H)-dione-2,2-d2
CAS 2839561-37-2C22H19N3O6
Orb3135160
CAS 2378428-15-8C24H20F3N3O8
7-MAD-MDCPT hydrochloride
CAS 2740593-09-1C22H20ClN3O6
Anticancer agent 216
CAS 2916406-02-3C23H21N3O6
Anticancer agent 217
CAS 2916406-04-5C23H21N3O6
Anticancer agent 218
CAS 2916406-46-5C23H19F2N3O6
Anticancer agent 219
CAS 2916407-63-9C23H19F2N3O6
![(S)-14-(Chloromethyl)-7-ethyl-7-hydroxy-10,13-dihydro-11H-[1,3]dioxolo[4,5-g]pyrano[3 inverted exclamation mark,4 inverted exclamation mark:6,7]indolizino[1,2-b]quinoline-8,11(7H)-dione-2,2-d2 chemical structure, C22H17ClN2O6, CAS 2911576-56-0](/s/FGIXZILUSHAOJP-GFIFTMAESA-N.svg)
(S)-14-(Chloromethyl)-7-ethyl-7-hydroxy-10,13-dihydro-11H-[1,3]dioxolo[4,5-g]pyrano[3 inverted exclamation mark,4 inverted exclamation mark:6,7]indolizino[1,2-b]quinoline-8,11(7H)-dione-2,2-d2
CAS 2911576-56-0C22H17ClN2O6