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Murcko scaffold

Ring system with 5 rings and 29 atoms

16 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
29
Chemicals
16
With full pages
3
Scaffold SMILES

O=C1C(=O)N(CN2N=C(c3ccccc3)CC2c2ccccc2)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C(=O)N(CN2N=C(c3ccccc3)CC2c2ccccc2)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

1-((3-(4-Methoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione chemical structure, C25H21N3O3, CAS 331944-69-5
1-((3-(4-Methoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione
CAS 331944-69-5C25H21N3O3
5-Bromo-1-((3-(4-methoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione chemical structure, C25H20BrN3O3, CAS 331944-68-4
5-Bromo-1-((3-(4-methoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione
CAS 331944-68-4C25H20BrN3O3
5-Bromo-1-[[5-(4-methoxyphenyl)-3-(3-nitrophenyl)-3,4-dihydropyrazol-2-yl]methyl]indole-2,3-dione chemical structure, C25H19BrN4O5, CAS 312734-17-1
5-Bromo-1-[[5-(4-methoxyphenyl)-3-(3-nitrophenyl)-3,4-dihydropyrazol-2-yl]methyl]indole-2,3-dione
CAS 312734-17-1C25H19BrN4O5
1-((5-(4-Bromophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione chemical structure, C25H20BrN3O3, CAS 331988-53-5
1-((5-(4-Bromophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione
CAS 331988-53-5C25H20BrN3O3
5-Bromo-1-((5-(4-bromophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione chemical structure, C25H19Br2N3O3, CAS 331988-54-6
5-Bromo-1-((5-(4-bromophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione
CAS 331988-54-6C25H19Br2N3O3
1-((3,5-Bis(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)-5-bromoindoline-2,3-dione chemical structure, C26H22BrN3O4, CAS 331988-66-0
1-((3,5-Bis(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)-5-bromoindoline-2,3-dione
CAS 331988-66-0C26H22BrN3O4
5-Bromo-1-((3-(4-bromophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione chemical structure, C24H16Br2FN3O2, CAS 337932-32-8
5-Bromo-1-((3-(4-bromophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione
CAS 337932-32-8C24H16Br2FN3O2
5-Bromo-1-((5-(2-chlorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione chemical structure, C25H19BrClN3O3, CAS 337932-35-1
5-Bromo-1-((5-(2-chlorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione
CAS 337932-35-1C25H19BrClN3O3
1-{[3-(4-Bromophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]methyl}-1H-indole-2,3-dione chemical structure, C24H17BrFN3O2, CAS 312596-58-0
1-{[3-(4-Bromophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]methyl}-1H-indole-2,3-dione
CAS 312596-58-0C24H17BrFN3O2
1-((3-(4-Bromophenyl)-5-(2-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione chemical structure, C25H20BrN3O3, CAS 312596-59-1
1-((3-(4-Bromophenyl)-5-(2-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione
CAS 312596-59-1C25H20BrN3O3
1-((5-(2-Chlorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione chemical structure, C25H20ClN3O3, CAS 361473-83-8
1-((5-(2-Chlorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione
CAS 361473-83-8C25H20ClN3O3
5-Bromo-1-((3-(4-bromophenyl)-5-(2-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione chemical structure, C25H19Br2N3O3, CAS 391889-81-9
5-Bromo-1-((3-(4-bromophenyl)-5-(2-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione
CAS 391889-81-9C25H19Br2N3O3
1-((3-(4-Methoxyphenyl)-5-(3-nitrophenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione chemical structure, C25H20N4O5, CAS 331988-69-3
1-((3-(4-Methoxyphenyl)-5-(3-nitrophenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione
CAS 331988-69-3C25H20N4O5
1-((3-(4-Bromophenyl)-5-(2-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione chemical structure, C24H17BrClN3O2, CAS 361479-10-9
1-((3-(4-Bromophenyl)-5-(2-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione
CAS 361479-10-9C24H17BrClN3O2
1-((3,5-Bis(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione chemical structure, C26H23N3O4, CAS 361160-38-5
1-((3,5-Bis(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione
CAS 361160-38-5C26H23N3O4
5-Bromo-1-((3-(4-bromophenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione chemical structure, C24H17Br2N3O2, CAS 361479-09-6
5-Bromo-1-((3-(4-bromophenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)methyl)indoline-2,3-dione
CAS 361479-09-6C24H17Br2N3O2