CompoundList
Sign in
Murcko scaffold

Ring system with 5 rings and 28 atoms

6 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
28
Chemicals
6
With full pages
2
Scaffold SMILES

O=C(OC1CC2CCC(C1)[N+]21CCCC1)C(c1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OC1CC2CCC(C1)[N+]21CCCC1)C(c1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Trosec chemical structure, C25H30NO3+, CAS 10360-09-5
Trosec
CAS 10360-09-5C25H30NO3+
Spiro(8-azoniabicyclo(3.2.1)octane-8,1'-pyrrolidinium), 3-hydroxy-, chloride, benzilate chemical structure, C25H30ClNO3, CAS 73954-17-3
Spiro(8-azoniabicyclo(3.2.1)octane-8,1'-pyrrolidinium), 3-hydroxy-, chloride, benzilate
CAS 73954-17-3C25H30ClNO3
Trospium chloride chemical structure, C25H30ClNO3, CAS 10405-02-4
Trospium chloride
CAS 10405-02-4C25H30ClNO3
Trospium chemical structure, C25H30NO3+, CAS 47608-32-2
Trospium
CAS 47608-32-2C25H30NO3+
[(1S,5R)-Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-yl] 2-hydroxy-2,2-diphenylacetate bromide chemical structure, C25H30BrNO3
[(1S,5R)-Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-yl] 2-hydroxy-2,2-diphenylacetate bromide
C25H30BrNO3
[(1S,5R)-Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-yl] 2-hydroxy-2,2-diphenylacetate, hydrochloride chemical structure, C25H31ClNO3+
[(1S,5R)-Spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-yl] 2-hydroxy-2,2-diphenylacetate, hydrochloride
C25H31ClNO3+