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Murcko scaffold

Ring system with 4 rings and 30 atoms

20 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
30
Chemicals
20
With full pages
1
Scaffold SMILES

O=S(=O)(NCC(c1ccccc1)N1CCN(c2ccccc2)CC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(NCC(c1ccccc1)N1CCN(c2ccccc2)CC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

N-[2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-phenylethyl]-4-methylbenzenesulfonamide chemical structure, C26H31N3O3S, CAS 852688-88-1
N-[2-[4-(4-Methoxyphenyl)piperazin-1-yl]-2-phenylethyl]-4-methylbenzenesulfonamide
CAS 852688-88-1C26H31N3O3S
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-2,4-dimethylbenzenesulfonamide chemical structure, C28H36N4O2S, CAS 1005298-06-5
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-2,4-dimethylbenzenesulfonamide
CAS 1005298-06-5C28H36N4O2S
N-{2-[4-(Dimethylamino)phenyl]-2-(4-phenylpiperazin-1-yl)ethyl}benzenesulfonamide chemical structure, C26H32N4O2S, CAS 932363-67-2
N-{2-[4-(Dimethylamino)phenyl]-2-(4-phenylpiperazin-1-yl)ethyl}benzenesulfonamide
CAS 932363-67-2C26H32N4O2S
N-{2-[4-(Dimethylamino)phenyl]-2-(4-phenylpiperazin-1-yl)ethyl}-4-methylbenzene-1-sulfonamide chemical structure, C27H34N4O2S, CAS 932293-41-9
N-{2-[4-(Dimethylamino)phenyl]-2-(4-phenylpiperazin-1-yl)ethyl}-4-methylbenzene-1-sulfonamide
CAS 932293-41-9C27H34N4O2S
N-{2-[4-(Dimethylamino)phenyl]-2-(4-phenylpiperazin-1-yl)ethyl}-4-methoxybenzene-1-sulfonamide chemical structure, C27H34N4O3S, CAS 932505-97-0
N-{2-[4-(Dimethylamino)phenyl]-2-(4-phenylpiperazin-1-yl)ethyl}-4-methoxybenzene-1-sulfonamide
CAS 932505-97-0C27H34N4O3S
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-4-fluorobenzenesulfonamide chemical structure, C26H31FN4O2S, CAS 932501-97-8
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-4-fluorobenzenesulfonamide
CAS 932501-97-8C26H31FN4O2S
4-Chloro-N-(2-(4-(dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)benzenesulfonamide chemical structure, C26H31ClN4O2S, CAS 932363-70-7
4-Chloro-N-(2-(4-(dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)benzenesulfonamide
CAS 932363-70-7C26H31ClN4O2S
N-{2-[4-(Dimethylamino)phenyl]-2-[4-(4-fluorophenyl)piperazin-1-yl]ethyl}benzenesulfonamide chemical structure, C26H31FN4O2S, CAS 932293-43-1
N-{2-[4-(Dimethylamino)phenyl]-2-[4-(4-fluorophenyl)piperazin-1-yl]ethyl}benzenesulfonamide
CAS 932293-43-1C26H31FN4O2S
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-3-methylbenzenesulfonamide chemical structure, C27H34N4O2S, CAS 946288-15-9
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-3-methylbenzenesulfonamide
CAS 946288-15-9C27H34N4O2S
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-3,4-dimethylbenzenesulfonamide chemical structure, C28H36N4O2S, CAS 946317-03-9
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-3,4-dimethylbenzenesulfonamide
CAS 946317-03-9C28H36N4O2S
N-{2-[4-(Dimethylamino)phenyl]-2-(4-phenylpiperazin-1-yl)ethyl}-4-ethylbenzene-1-sulfonamide chemical structure, C28H36N4O2S, CAS 946366-60-5
N-{2-[4-(Dimethylamino)phenyl]-2-(4-phenylpiperazin-1-yl)ethyl}-4-ethylbenzene-1-sulfonamide
CAS 946366-60-5C28H36N4O2S
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-2-fluorobenzenesulfonamide chemical structure, C26H31FN4O2S, CAS 946244-89-9
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-2-fluorobenzenesulfonamide
CAS 946244-89-9C26H31FN4O2S
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-3-fluorobenzenesulfonamide chemical structure, C26H31FN4O2S, CAS 946288-19-3
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-3-fluorobenzenesulfonamide
CAS 946288-19-3C26H31FN4O2S
3-Chloro-N-(2-(4-(dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)benzenesulfonamide chemical structure, C26H31ClN4O2S, CAS 946366-63-8
3-Chloro-N-(2-(4-(dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)benzenesulfonamide
CAS 946366-63-8C26H31ClN4O2S
2-Chloro-N-(2-(4-(dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)benzenesulfonamide chemical structure, C26H31ClN4O2S, CAS 946244-92-4
2-Chloro-N-(2-(4-(dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)benzenesulfonamide
CAS 946244-92-4C26H31ClN4O2S
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-2,5-dimethylbenzenesulfonamide chemical structure, C28H36N4O2S, CAS 946366-66-1
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-2,5-dimethylbenzenesulfonamide
CAS 946366-66-1C28H36N4O2S
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-4-fluoro-2-methylbenzenesulfonamide chemical structure, C27H33FN4O2S, CAS 946288-27-3
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-4-fluoro-2-methylbenzenesulfonamide
CAS 946288-27-3C27H33FN4O2S
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-4-fluoro-3-methylbenzenesulfonamide chemical structure, C27H33FN4O2S, CAS 946244-95-7
N-(2-(4-(Dimethylamino)phenyl)-2-(4-phenylpiperazin-1-yl)ethyl)-4-fluoro-3-methylbenzenesulfonamide
CAS 946244-95-7C27H33FN4O2S
N-(2-(4-(Dimethylamino)phenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)ethyl)-3-methylbenzenesulfonamide chemical structure, C27H33FN4O2S, CAS 946244-98-0
N-(2-(4-(Dimethylamino)phenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)ethyl)-3-methylbenzenesulfonamide
CAS 946244-98-0C27H33FN4O2S
N-(2-(4-(Dimethylamino)phenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)ethyl)-4-methylbenzenesulfonamide chemical structure, C27H33FN4O2S, CAS 946317-15-3
N-(2-(4-(Dimethylamino)phenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)ethyl)-4-methylbenzenesulfonamide
CAS 946317-15-3C27H33FN4O2S