Murcko scaffold
Ring system with 5 rings and 24 atoms
34 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 24
- Chemicals
- 34
- With full pages
- 6
Scaffold SMILES
c1ccc(C2CCC3c4ccccc4OC23c2ccccc2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 34 of 34 chemicals
Rocaglamide J
CAS 147059-47-0C28H28O8
Rocaglamide
CAS 84573-16-0C29H31NO7
Aglafolin
CAS 143901-35-3C28H28O8
Rocaglaol
CAS 147059-46-9C26H26O6
Didesmethylrocaglamide
CAS 177262-30-5C27H27NO7
Desmethylrocaglamide
CAS 146408-78-8C28H29NO7
![(1S,3S,3aR,8bS)-6,8-Dimethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-1,8b-diol chemical structure, C26H26O6, CAS 136850-46-9](/s/RRVZOJQBRVGMMK-JWWGNVLFSA-N.svg)
(1S,3S,3aR,8bS)-6,8-Dimethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-1,8b-diol
CAS 136850-46-9C26H26O6
Rocagloic acid
CAS 190385-15-0C27H26O8
Rocaglamide I
CAS 189322-68-7C31H33NO9
3'-Methoxyrocaglamide
CAS 189322-69-8C30H33NO8
3'-Hydroxyrocaglamide
CAS 189322-67-6C29H31NO8
1-O-Formylrocagloic acid
CAS 917393-83-0C28H26O9
![Methyl (1R,2R,3S,3aR,8bS)-2,3,3a,8b-tetrahydro-1,6,8b-trihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxylate chemical structure, C27H26O8, CAS 960365-65-5](/s/HYLOONIBWUNKDH-PXIJUOARSA-N.svg)
Methyl (1R,2R,3S,3aR,8bS)-2,3,3a,8b-tetrahydro-1,6,8b-trihydroxy-8-methoxy-3a-(4-methoxyphenyl)-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxylate
CAS 960365-65-5C27H26O8
FL3 (flavagline)
CAS 1186012-80-5C25H23BrO5
Rohinitib
CAS 1139253-73-8C29H31NO8
![(1R,2R,3S,3aR,8bS)-1,8b-Dihydroxy-N,6,8-trimethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide chemical structure, C28H29NO8, CAS 1352914-52-3](/s/KLSIFOJPWJBRFH-GWNOIRNCSA-N.svg)
(1R,2R,3S,3aR,8bS)-1,8b-Dihydroxy-N,6,8-trimethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxamide
CAS 1352914-52-3C28H29NO8
(+)-N-Methoxy rocaglamide
CAS 1352914-53-4C28H29NO8
eIF4A3-IN-16
CAS 1402931-74-1C29H28O8
eIF4A3-IN-18
CAS 1402931-84-3C29H28N2O6
eIF4A3-IN-13
CAS 1402931-85-4C28H28ClNO6
Antiproliferative agent-64
CAS 1139263-21-0C29H28N2O6
eIF4A3-IN-10
CAS 1402931-72-9C29H29NO8
eIF4A3-IN-17
CAS 1402931-75-2C28H25NO7
eIF4A3-IN-11
CAS 1402931-70-7C29H28O9
- eIF4A3-IN-141402931-65-0C27H27NO7
- eIF4A3-IN-151402931-66-1C28H29NO7
- eIF4A3-IN-91402931-71-8C28H27NO8
- eIF4A3-IN-121402931-76-3C27H25ClO7
- (+)-Rocaglamide1699754-37-4C29H31NO7
- Silvestrol aglycone (enantiomer)1112993-18-6C27H26O8
- Rel-(1R,2R,3S,3aR,8bS)-3a-(4-bromophenyl)-1,8b-dihydroxy-N,6,8-trimethoxy-3-phenyl-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-2-carboxamide256497-58-2C27H26BrNO7
- eIF4A3-IN-72374759-82-5C26H25NO7
- (1S,2S,3R,3aS,8bR)-1,8b-Dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]benzofuran-2-carboxylic acid1352914-51-2C27H26O8
- Antiviral agent 483032868-59-7C27H25BrO7
Related scaffolds
Same ring framework with different atoms or bond orders
