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Murcko scaffold

Ring system with 4 rings and 22 atoms

17 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
17
With full pages
4
Scaffold SMILES

O=C(Nc1ccccc1)Oc1ccc2c(c1)C1CCNC1N2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)Oc1ccc2c(c1)C1CCNC1N2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

(-)-Phenserine chemical structure, C20H23N3O2, CAS 101246-66-6
(-)-Phenserine
CAS 101246-66-6C20H23N3O2
Eseroline, phenylcarbamate chemical structure, C20H23N3O2, CAS 2469279-26-1
Eseroline, phenylcarbamate
CAS 2469279-26-1C20H23N3O2
Phenserine tartrate chemical structure, C24H29N3O8, CAS 156910-61-1
Phenserine tartrate
CAS 156910-61-1C24H29N3O8
(-)-Cymserine chemical structure, C23H29N3O2, CAS 145209-39-8
(-)-Cymserine
CAS 145209-39-8C23H29N3O2
Buntanetap chemical structure, C20H23N3O2, CAS 116839-68-0
Buntanetap
CAS 116839-68-0C20H23N3O2
1,3alpha,8-Trimethyl-1,2,3,3alpha,8,8alpha-hexahydropyrrolo[2,3-b]indol-5-yl-3-cyanophenylcarbamate chemical structure, C21H22N4O2, CAS 1220811-22-2
1,3alpha,8-Trimethyl-1,2,3,3alpha,8,8alpha-hexahydropyrrolo[2,3-b]indol-5-yl-3-cyanophenylcarbamate
CAS 1220811-22-2C21H22N4O2
CHF-2819 free base chemical structure, C22H27N3O3, CAS 910661-75-5
CHF-2819 free base
CAS 910661-75-5C22H27N3O3
1,3a-Dimethyl-1-oxo-1,2,3,3a,8,8a-hexahydro-1lambda~5~-pyrrolo[2,3-b]indol-5-yl hydrogen (2-ethylphenyl)carbonimidate--hydrogen chloride (1/1) chemical structure, C21H26ClN3O3, CAS 223585-99-7
1,3a-Dimethyl-1-oxo-1,2,3,3a,8,8a-hexahydro-1lambda~5~-pyrrolo[2,3-b]indol-5-yl hydrogen (2-ethylphenyl)carbonimidate--hydrogen chloride (1/1)
CAS 223585-99-7C21H26ClN3O3
Bisnorcymserine chemical structure, C21H25N3O2, CAS 219920-81-7
Bisnorcymserine
CAS 219920-81-7C21H25N3O2
Bisnorcymserine tartrate chemical structure, C25H31N3O8, CAS 887028-62-8
Bisnorcymserine tartrate
CAS 887028-62-8C25H31N3O8
N1-Norposiphen chemical structure, C19H21N3O2, CAS 145209-44-5
N1-Norposiphen
CAS 145209-44-5C19H21N3O2
N8-Norposiphen chemical structure, C18H19N3O2, CAS 193604-45-4
N8-Norposiphen
CAS 193604-45-4C18H19N3O2
Ganstigmine hydrochloride chemical structure, C21H26ClN3O3, CAS 412044-92-9
Ganstigmine hydrochloride
CAS 412044-92-9C21H26ClN3O3
[(3R,3aS,8bS)-3,8b-Dimethyl-3-oxido-1,2,3a,4-tetrahydropyrrolo[2,3-b]indol-3-ium-7-yl] N-(2-ethylphenyl)carbamate chemical structure, C21H25N3O3, CAS 697223-90-8
[(3R,3aS,8bS)-3,8b-Dimethyl-3-oxido-1,2,3a,4-tetrahydropyrrolo[2,3-b]indol-3-ium-7-yl] N-(2-ethylphenyl)carbamate
CAS 697223-90-8C21H25N3O3
Chf-2819 chemical structure, C22H28ClN3O3, CAS 1177926-59-8
Chf-2819
CAS 1177926-59-8C22H28ClN3O3
Buntanetap tartrate chemical structure, C24H29N3O8, CAS 865795-23-9
Buntanetap tartrate
CAS 865795-23-9C24H29N3O8
(3aR,8aS)-3a-Methyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl phenylcarbamate chemical structure, C18H19N3O2, CAS 207729-71-3
(3aR,8aS)-3a-Methyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl phenylcarbamate
CAS 207729-71-3C18H19N3O2