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Murcko scaffold

Ring system with 4 rings and 28 atoms

42 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
42
With full pages
8
Scaffold SMILES

O=C1CCc2ccc(OCCCCN3CCN(c4ccccc4)CC3)cc2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCc2ccc(OCCCCN3CCN(c4ccccc4)CC3)cc2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

Aripiprazole chemical structure, C23H27Cl2N3O2, CAS 129722-12-9
Aripiprazole
CAS 129722-12-9C23H27Cl2N3O2
7-(4-(4-(2,3-Dichloro-4-hydroxy-phenyl)piperazin-1-yl)butoxy)-3,4-dihydro-1H-quinolin-2-one chemical structure, C23H27Cl2N3O3, CAS 173456-49-0
7-(4-(4-(2,3-Dichloro-4-hydroxy-phenyl)piperazin-1-yl)butoxy)-3,4-dihydro-1H-quinolin-2-one
CAS 173456-49-0C23H27Cl2N3O3
Aripiprazole N4-oxide chemical structure, C23H27Cl2N3O3, CAS 573691-11-9
Aripiprazole N4-oxide
CAS 573691-11-9C23H27Cl2N3O3
Aripiprazole N,N-dioxide chemical structure, C23H27Cl2N3O4, CAS 573691-13-1
Aripiprazole N,N-dioxide
CAS 573691-13-1C23H27Cl2N3O4
Aripiprazole N1-oxide chemical structure, C23H27Cl2N3O3, CAS 573691-09-5
Aripiprazole N1-oxide
CAS 573691-09-5C23H27Cl2N3O3
F3SS4E3Lfn chemical structure, C23H27Cl2N3O3, CAS 805240-77-1
F3SS4E3Lfn
CAS 805240-77-1C23H27Cl2N3O3
7-[4-[4-(2-Aminophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone chemical structure, C23H30N4O2, CAS 203395-89-5
7-[4-[4-(2-Aminophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
CAS 203395-89-5C23H30N4O2
Deschloroaripiprazole chemical structure, C23H28ClN3O2, CAS 203395-81-7
Deschloroaripiprazole
CAS 203395-81-7C23H28ClN3O2
2-Deschloro aripiprazole chemical structure, C23H28ClN3O2, CAS 203395-82-8
2-Deschloro aripiprazole
CAS 203395-82-8C23H28ClN3O2
2(1H)-Quinolinone, 7-[4-[4-(2-chloro-3-methylphenyl)-1-piperazinyl]butoxy]-3,4-dihydro- chemical structure, C24H30ClN3O2, CAS 129722-18-5
2(1H)-Quinolinone, 7-[4-[4-(2-chloro-3-methylphenyl)-1-piperazinyl]butoxy]-3,4-dihydro-
CAS 129722-18-5C24H30ClN3O2
7-[4-[4-(2,5-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone chemical structure, C23H27Cl2N3O2, CAS 203395-73-7
7-[4-[4-(2,5-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
CAS 203395-73-7C23H27Cl2N3O2
7-[4-[4-(4-Chlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone chemical structure, C23H28ClN3O2, CAS 203395-83-9
7-[4-[4-(4-Chlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
CAS 203395-83-9C23H28ClN3O2
7-(4-(4-(2,3,5-Trichlorophenyl)piperazin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one chemical structure, C23H26Cl3N3O2, CAS 129722-22-1
7-(4-(4-(2,3,5-Trichlorophenyl)piperazin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one
CAS 129722-22-1C23H26Cl3N3O2
7-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one chemical structure, C24H31N3O3, CAS 129722-23-2
7-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butoxy)-3,4-dihydroquinolin-2(1H)-one
CAS 129722-23-2C24H31N3O3
7-[4-[4-(2-Fluorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone chemical structure, C23H28FN3O2, CAS 203395-85-1
7-[4-[4-(2-Fluorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
CAS 203395-85-1C23H28FN3O2
2-[4-[4-[(1,2,3,4-Tetrahydro-2-oxo-7-quinolinyl)oxy]butyl]-1-piperazinyl]benzonitrile chemical structure, C24H28N4O2, CAS 203395-90-8
2-[4-[4-[(1,2,3,4-Tetrahydro-2-oxo-7-quinolinyl)oxy]butyl]-1-piperazinyl]benzonitrile
CAS 203395-90-8C24H28N4O2
7-[4-[4-(3-Chloro-2-methylphenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone chemical structure, C24H30ClN3O2, CAS 203395-60-2
7-[4-[4-(3-Chloro-2-methylphenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
CAS 203395-60-2C24H30ClN3O2
7-[4-[4-(2-Bromophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one chemical structure, C23H28BrN3O2, CAS 203395-84-0
7-[4-[4-(2-Bromophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
CAS 203395-84-0C23H28BrN3O2
7-[4-[4-(5-Chloro-2-methylphenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone chemical structure, C24H30ClN3O2, CAS 203395-62-4
7-[4-[4-(5-Chloro-2-methylphenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
CAS 203395-62-4C24H30ClN3O2
7-[4-[4-(2,4-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone chemical structure, C23H27Cl2N3O2, CAS 203395-72-6
7-[4-[4-(2,4-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
CAS 203395-72-6C23H27Cl2N3O2
7-[4-[4-(3,4-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone chemical structure, C23H27Cl2N3O2, CAS 203395-75-9
7-[4-[4-(3,4-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
CAS 203395-75-9C23H27Cl2N3O2
Aripiprazole monohydrate chemical structure, C23H29Cl2N3O3, CAS 851220-85-4
Aripiprazole monohydrate
CAS 851220-85-4C23H29Cl2N3O3
Aripiprazole maleate chemical structure, C27H31Cl2N3O6, CAS 129722-16-3
Aripiprazole maleate
CAS 129722-16-3C27H31Cl2N3O6
Vex3BL2H9X chemical structure, C23H27Cl2N3O6S, CAS 805240-76-0
Vex3BL2H9X
CAS 805240-76-0C23H27Cl2N3O6S