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Murcko scaffold

Ring system with 3 rings and 13 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
11
With full pages
1
Scaffold SMILES

c1nc(C2CC2)sc1B1OCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1nc(C2CC2)sc1B1OCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C12H18BNO2S, CAS 1245524-04-2
2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 1245524-04-2C12H18BNO2S
1-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-thiazolyl]cyclopropanecarboxylic acid methyl ester chemical structure, C14H20BNO4S, CAS 1620318-46-8
1-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-thiazolyl]cyclopropanecarboxylic acid methyl ester
CAS 1620318-46-8C14H20BNO4S
4-Ethyl-2-(cyclopropyl)thiazole-5-boronic acid pinacol ester chemical structure, C14H22BNO2S, CAS 2223035-73-0
4-Ethyl-2-(cyclopropyl)thiazole-5-boronic acid pinacol ester
CAS 2223035-73-0C14H22BNO2S
4-(iso-Propyl)-2-(cyclopropyl)thiazole-5-boronic acid pinacol ester chemical structure, C15H24BNO2S, CAS 2223055-45-4
4-(iso-Propyl)-2-(cyclopropyl)thiazole-5-boronic acid pinacol ester
CAS 2223055-45-4C15H24BNO2S
4-Chloro-2-(cyclopropyl)thiazole-5-boronic acid pinacol ester chemical structure, C12H17BClNO2S, CAS 2223047-84-3
4-Chloro-2-(cyclopropyl)thiazole-5-boronic acid pinacol ester
CAS 2223047-84-3C12H17BClNO2S
2-Cyclopropyl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole chemical structure, C13H20BNO2S, CAS 2223052-34-2
2-Cyclopropyl-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-thiazole
CAS 2223052-34-2C13H20BNO2S
4-Bromo-2-(cyclopropyl)thiazole-5-boronic acid pinacol ester chemical structure, C12H17BBrNO2S, CAS 2223013-01-0
4-Bromo-2-(cyclopropyl)thiazole-5-boronic acid pinacol ester
CAS 2223013-01-0C12H17BBrNO2S
2-(Cyclopropyl-d5)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C12H18BNO2S, CAS 2710290-69-8
2-(Cyclopropyl-d5)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 2710290-69-8C12H18BNO2S
2-(Cyclopropyl-d5)-4-(methyl-d3)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C13H20BNO2S, CAS 2710290-72-3
2-(Cyclopropyl-d5)-4-(methyl-d3)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 2710290-72-3C13H20BNO2S
2-(Cyclopropyl-d5)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole-4-d chemical structure, C12H18BNO2S, CAS 2710290-70-1
2-(Cyclopropyl-d5)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole-4-d
CAS 2710290-70-1C12H18BNO2S
2-Cyclopropyl-4-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole chemical structure, C13H20BNO3S, CAS 2819706-02-8
2-Cyclopropyl-4-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole
CAS 2819706-02-8C13H20BNO3S