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Murcko scaffold

1H-Purine-2,6-dione, 3,7-dihydro-1,7-bis(phenylmethyl)- scaffold

26 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
26
With full pages
3
Scaffold SMILES

O=c1[nH]c2ncn(Cc3ccccc3)c2c(=O)n1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1H-Purine-2,6-dione, 3,7-dihydro-1,7-bis(phenylmethyl)- page
Murcko scaffold O=c1[nH]c2ncn(Cc3ccccc3)c2c(=O)n1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

7-Benzyl-1-(3-chlorobenzyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione chemical structure, C20H17ClN4O2, CAS 442871-24-1
7-Benzyl-1-(3-chlorobenzyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione
CAS 442871-24-1C20H17ClN4O2
2-((1,7-Dibenzyl-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)thio)acetic acid chemical structure, C22H20N4O4S, CAS 313660-79-6
2-((1,7-Dibenzyl-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)thio)acetic acid
CAS 313660-79-6C22H20N4O4S
1-Benzyl-8-bromo-7-(4-chlorobenzyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione chemical structure, C20H16BrClN4O2, CAS 331840-00-7
1-Benzyl-8-bromo-7-(4-chlorobenzyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione
CAS 331840-00-7C20H16BrClN4O2
8-Bromo-1,7-bis(2-chlorobenzyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione chemical structure, C20H15BrCl2N4O2, CAS 303973-59-3
8-Bromo-1,7-bis(2-chlorobenzyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione
CAS 303973-59-3C20H15BrCl2N4O2
8-Bromo-7-(2-chlorobenzyl)-1-(4-chlorobenzyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione chemical structure, C20H15BrCl2N4O2, CAS 303973-58-2
8-Bromo-7-(2-chlorobenzyl)-1-(4-chlorobenzyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione
CAS 303973-58-2C20H15BrCl2N4O2
8-Bromo-7-(2-chlorobenzyl)-3-methyl-1-(4-methylbenzyl)-3,7-dihydro-1H-purine-2,6-dione chemical structure, C21H18BrClN4O2, CAS 303973-57-1
8-Bromo-7-(2-chlorobenzyl)-3-methyl-1-(4-methylbenzyl)-3,7-dihydro-1H-purine-2,6-dione
CAS 303973-57-1C21H18BrClN4O2
1,7-Dibenzyl-8-(diethylamino)-3-methyl-3,7-dihydro-1H-purine-2,6-dione chemical structure, C24H27N5O2, CAS 294854-21-0
1,7-Dibenzyl-8-(diethylamino)-3-methyl-3,7-dihydro-1H-purine-2,6-dione
CAS 294854-21-0C24H27N5O2
1,7-Dibenzyl-3-methyl-8-(methylsulfanyl)-3,7-dihydro-1H-purine-2,6-dione chemical structure, C21H20N4O2S, CAS 330990-57-3
1,7-Dibenzyl-3-methyl-8-(methylsulfanyl)-3,7-dihydro-1H-purine-2,6-dione
CAS 330990-57-3C21H20N4O2S
8-(Ethylsulfanyl)-3-methyl-1,7-bis(phenylmethyl)-3,7-dihydro-1H-purine-2,6-dione chemical structure, C22H22N4O2S, CAS 301195-28-8
8-(Ethylsulfanyl)-3-methyl-1,7-bis(phenylmethyl)-3,7-dihydro-1H-purine-2,6-dione
CAS 301195-28-8C22H22N4O2S
Ethyl [(1,7-dibenzyl-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)sulfanyl]acetate chemical structure, C24H24N4O4S, CAS 301354-08-5
Ethyl [(1,7-dibenzyl-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)sulfanyl]acetate
CAS 301354-08-5C24H24N4O4S
2-[(1,7-Dibenzyl-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)sulfanyl]acetamide chemical structure, C22H21N5O3S, CAS 330990-56-2
2-[(1,7-Dibenzyl-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)sulfanyl]acetamide
CAS 330990-56-2C22H21N5O3S
1,7-Dibenzyl-3-methyl-8-(methylamino)purine-2,6-dione chemical structure, C21H21N5O2, CAS 294854-24-3
1,7-Dibenzyl-3-methyl-8-(methylamino)purine-2,6-dione
CAS 294854-24-3C21H21N5O2
1,7-Dibenzyl-8-(dimethylamino)-3-methylpurine-2,6-dione chemical structure, C22H23N5O2, CAS 294854-22-1
1,7-Dibenzyl-8-(dimethylamino)-3-methylpurine-2,6-dione
CAS 294854-22-1C22H23N5O2
1-Benzyl-8-bromo-7-(2-chlorobenzyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione chemical structure, C20H16BrClN4O2, CAS 303973-62-8
1-Benzyl-8-bromo-7-(2-chlorobenzyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione
CAS 303973-62-8C20H16BrClN4O2
1-Benzyl-8-bromo-3-methyl-7-(4-methylbenzyl)-3,7-dihydro-1H-purine-2,6-dione chemical structure, C21H19BrN4O2, CAS 332905-07-4
1-Benzyl-8-bromo-3-methyl-7-(4-methylbenzyl)-3,7-dihydro-1H-purine-2,6-dione
CAS 332905-07-4C21H19BrN4O2
1,7-Dibenzyl-8-bromo-3-methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione chemical structure, C20H17BrN4O2, CAS 114145-28-7
1,7-Dibenzyl-8-bromo-3-methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
CAS 114145-28-7C20H17BrN4O2
8-Bromo-7-[(2-chlorophenyl)methyl]-3-methyl-1-[(3-methylphenyl)methyl]purine-2,6-dione chemical structure, C21H18BrClN4O2, CAS 371128-51-7
8-Bromo-7-[(2-chlorophenyl)methyl]-3-methyl-1-[(3-methylphenyl)methyl]purine-2,6-dione
CAS 371128-51-7C21H18BrClN4O2
1,7-Dibenzyl-8-((2-hydroxyethyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione chemical structure, C22H22N4O3S, CAS 331444-40-7
1,7-Dibenzyl-8-((2-hydroxyethyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione
CAS 331444-40-7C22H22N4O3S
1,7-Dibenzyl-3-methyl-8-[(2-methylpropyl)sulfanyl]-2,3,6,7-tetrahydro-1H-purine-2,6-dione chemical structure, C24H26N4O2S, CAS 326919-43-1
1,7-Dibenzyl-3-methyl-8-[(2-methylpropyl)sulfanyl]-2,3,6,7-tetrahydro-1H-purine-2,6-dione
CAS 326919-43-1C24H26N4O2S
1,7-Dibenzyl-8-((2-hydroxypropyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione chemical structure, C23H24N4O3S, CAS 368889-41-2
1,7-Dibenzyl-8-((2-hydroxypropyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione
CAS 368889-41-2C23H24N4O3S
1,7-Dibenzyl-3-methyl-8-propan-2-ylsulfanylpurine-2,6-dione chemical structure, C23H24N4O2S, CAS 327168-29-6
1,7-Dibenzyl-3-methyl-8-propan-2-ylsulfanylpurine-2,6-dione
CAS 327168-29-6C23H24N4O2S
1,7-Dibenzyl-8-butylsulfanyl-3-methylpurine-2,6-dione chemical structure, C24H26N4O2S, CAS 330180-69-3
1,7-Dibenzyl-8-butylsulfanyl-3-methylpurine-2,6-dione
CAS 330180-69-3C24H26N4O2S
1,7-Dibenzyl-8-[(2-methoxyethyl)amino]-3-methyl-3,7-dihydro-1H-purine-2,6-dione chemical structure, C23H25N5O3, CAS 300591-57-5
1,7-Dibenzyl-8-[(2-methoxyethyl)amino]-3-methyl-3,7-dihydro-1H-purine-2,6-dione
CAS 300591-57-5C23H25N5O3
1H-Purine-2,6-dione, 3,7-dihydro-1,7-bis(phenylmethyl)- chemical structure, C19H16N4O2, CAS 140396-45-8
1H-Purine-2,6-dione, 3,7-dihydro-1,7-bis(phenylmethyl)-
CAS 140396-45-8C19H16N4O2