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Murcko scaffold

Ring system with 3 rings and 16 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
13
With full pages
4
Scaffold SMILES

O=c1c(=Cc2ccccc2)sc2ncnn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(=Cc2ccccc2)sc2ncnn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

(5Z)-5-[[3-Methoxy-4-(3-methylbutoxy)phenyl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one chemical structure, C17H19N3O3S, CAS 381704-69-4
(5Z)-5-[[3-Methoxy-4-(3-methylbutoxy)phenyl]methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
CAS 381704-69-4C17H19N3O3S
(5E)-5-(4-Chlorobenzylidene)[1,3]thiazolo[3,2-b][1,2,4]triazol-6(5H)-one chemical structure, C11H6ClN3OS, CAS 606956-26-7
(5E)-5-(4-Chlorobenzylidene)[1,3]thiazolo[3,2-b][1,2,4]triazol-6(5H)-one
CAS 606956-26-7C11H6ClN3OS
(5Z)-5-[(2-Fluorophenyl)methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one chemical structure, C11H6FN3OS, CAS 606957-16-8
(5Z)-5-[(2-Fluorophenyl)methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
CAS 606957-16-8C11H6FN3OS
(5Z)-5-[(2,5-Dimethoxyphenyl)methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one chemical structure, C13H11N3O3S, CAS 606951-35-3
(5Z)-5-[(2,5-Dimethoxyphenyl)methylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazol-6-one
CAS 606951-35-3C13H11N3O3S
5-(2-Propoxybenzylidene)[1,3]thiazolo[3,2-b][1,2,4]triazol-6(5H)-one chemical structure, C14H13N3O2S, CAS 608120-13-4
5-(2-Propoxybenzylidene)[1,3]thiazolo[3,2-b][1,2,4]triazol-6(5H)-one
CAS 608120-13-4C14H13N3O2S
5-(2-(Hexyloxy)benzylidene)(1,3)thiazolo(3,2-B)(1,2,4)triazol-6(5H)-one chemical structure, C17H19N3O2S, CAS 617695-15-5
5-(2-(Hexyloxy)benzylidene)(1,3)thiazolo(3,2-B)(1,2,4)triazol-6(5H)-one
CAS 617695-15-5C17H19N3O2S
5-(2-(Pentyloxy)benzylidene)(1,3)thiazolo(3,2-B)(1,2,4)triazol-6(5H)-one chemical structure, C16H17N3O2S, CAS 617694-58-3
5-(2-(Pentyloxy)benzylidene)(1,3)thiazolo(3,2-B)(1,2,4)triazol-6(5H)-one
CAS 617694-58-3C16H17N3O2S
5-(3-Meo-4-(octyloxy)benzylidene)(1,3)thiazolo(3,2-B)(1,2,4)triazol-6(5H)-one chemical structure, C20H25N3O3S, CAS 617694-28-7
5-(3-Meo-4-(octyloxy)benzylidene)(1,3)thiazolo(3,2-B)(1,2,4)triazol-6(5H)-one
CAS 617694-28-7C20H25N3O3S
5-(3-Ethoxy-4-propoxybenzylidene)(1,3)thiazolo(3,2-B)(1,2,4)triazol-6(5H)-one chemical structure, C16H17N3O3S, CAS 617694-36-7
5-(3-Ethoxy-4-propoxybenzylidene)(1,3)thiazolo(3,2-B)(1,2,4)triazol-6(5H)-one
CAS 617694-36-7C16H17N3O3S
(E)-5-(3-Ethoxy-4-(pentyloxy)benzylidene)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one chemical structure, C18H21N3O3S, CAS 616210-90-3
(E)-5-(3-Ethoxy-4-(pentyloxy)benzylidene)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one
CAS 616210-90-3C18H21N3O3S
5-(3-Fluorobenzylidene)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one chemical structure, C11H6FN3OS, CAS 606955-14-0
5-(3-Fluorobenzylidene)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one
CAS 606955-14-0C11H6FN3OS
(5E)-5-(2-Butoxybenzylidene)[1,3]thiazolo[3,2-b][1,2,4]triazol-6(5H)-one chemical structure, C15H15N3O2S, CAS 616210-96-9
(5E)-5-(2-Butoxybenzylidene)[1,3]thiazolo[3,2-b][1,2,4]triazol-6(5H)-one
CAS 616210-96-9C15H15N3O2S
5-[(2-Fluorophenyl)methylene]-2-methylthiazolo[3,2-b][1,2,4]triazol-6(5H)-one chemical structure, C12H8FN3OS, CAS 1173323-93-7
5-[(2-Fluorophenyl)methylene]-2-methylthiazolo[3,2-b][1,2,4]triazol-6(5H)-one
CAS 1173323-93-7C12H8FN3OS