CompoundList
Sign in
Murcko scaffold

Ring system with 5 rings and 32 atoms

9 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
32
Chemicals
9
With full pages
4
Scaffold SMILES

O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(-n3cncn3)nccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(-n3cncn3)nccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

Temsavir chemical structure, C24H23N7O4, CAS 701213-36-7
Temsavir
CAS 701213-36-7C24H23N7O4
Fostemsavir chemical structure, C25H26N7O8P, CAS 864953-29-7
Fostemsavir
CAS 864953-29-7C25H26N7O8P
1-(4-Benzoylpiperazin-1-yl)-2-[4-fluoro-7-(3-methyl-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione chemical structure, C23H20FN7O3, CAS 701213-27-6
1-(4-Benzoylpiperazin-1-yl)-2-[4-fluoro-7-(3-methyl-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione
CAS 701213-27-6C23H20FN7O3
Fostemsavir disodium chemical structure, C25H24N7Na2O8P, CAS 864953-31-1
Fostemsavir disodium
CAS 864953-31-1C25H24N7Na2O8P
Fostemsavir tromethamine chemical structure, C29H37N8O11P, CAS 864953-39-9
Fostemsavir tromethamine
CAS 864953-39-9C29H37N8O11P
Temsavir-D5 chemical structure, C24H23N7O4, CAS 1352806-42-8
Temsavir-D5
CAS 1352806-42-8C24H23N7O4
RefChem:370873 chemical structure, C33H42N7O8P, CAS 864953-38-8
RefChem:370873
CAS 864953-38-8C33H42N7O8P
Lithium 3-(2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl)-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)pyrrolo[2,3-c]pyridin-1-ide chemical structure, C24H22LiN7O4, CAS 1449413-05-1
Lithium 3-(2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl)-4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)pyrrolo[2,3-c]pyridin-1-ide
CAS 1449413-05-1C24H22LiN7O4
Fostemsavir dihydrate chemical structure, C25H30N7O10P, CAS 942117-71-7
Fostemsavir dihydrate
CAS 942117-71-7C25H30N7O10P