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Murcko scaffold

Ring system with 4 rings and 11 atoms

20 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
11
Chemicals
20
With full pages
4
Scaffold SMILES

C1CC2(CCO1)OC1CC2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1CC2(CCO1)OC1CC2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

{1-Amino-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-4-yl}methanol chemical structure, C10H17NO3, CAS 2253629-55-7
{1-Amino-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-4-yl}methanol
CAS 2253629-55-7C10H17NO3
4-({[(tert-Butoxy)carbonyl]amino}methyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylic acid chemical structure, C16H25NO6, CAS 2225142-48-1
4-({[(tert-Butoxy)carbonyl]amino}methyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylic acid
CAS 2225142-48-1C16H25NO6
Ethyl 4-(iodomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylate chemical structure, C13H19IO4, CAS 2225147-55-5
Ethyl 4-(iodomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylate
CAS 2225147-55-5C13H19IO4
Ethyl 4-(azidomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylate chemical structure, C13H19N3O4, CAS 2225146-56-3
Ethyl 4-(azidomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylate
CAS 2225146-56-3C13H19N3O4
4-Methyl-3-oxaspiro(bicyclo(2.1.1)hexane-2,4'-oxane)-1-carboxylic acid chemical structure, C11H16O4, CAS 2225146-57-4
4-Methyl-3-oxaspiro(bicyclo(2.1.1)hexane-2,4'-oxane)-1-carboxylic acid
CAS 2225146-57-4C11H16O4
Ethyl 4-(aminomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylate hydrochloride chemical structure, C13H22ClNO4, CAS 2225146-83-6
Ethyl 4-(aminomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylate hydrochloride
CAS 2225146-83-6C13H22ClNO4
Ethyl 4-(aminomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylate chemical structure, C13H21NO4, CAS 2225141-67-1
Ethyl 4-(aminomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylate
CAS 2225141-67-1C13H21NO4
4-(Aminomethyl)-3-oxaspiro(bicyclo(2.1.1)hexane-2,4'-oxane)-1-carboxylic acid hydrochloride chemical structure, C11H18ClNO4, CAS 2241140-50-9
4-(Aminomethyl)-3-oxaspiro(bicyclo(2.1.1)hexane-2,4'-oxane)-1-carboxylic acid hydrochloride
CAS 2241140-50-9C11H18ClNO4
4-(Aminomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylic acid chemical structure, C11H17NO4, CAS 2241139-89-7
4-(Aminomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylic acid
CAS 2241139-89-7C11H17NO4
tert-Butyl ((1-aminotetrahydro-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-pyran]-4-yl)methyl)carbamate chemical structure, C15H26N2O4, CAS 2241141-66-0
tert-Butyl ((1-aminotetrahydro-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-pyran]-4-yl)methyl)carbamate
CAS 2241141-66-0C15H26N2O4
4-(Hydroxymethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylic acid chemical structure, C11H16O5, CAS 2241128-51-6
4-(Hydroxymethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylic acid
CAS 2241128-51-6C11H16O5
4-Methyl-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-amine hydrochloride chemical structure, C10H18ClNO2, CAS 2241127-88-6
4-Methyl-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-amine hydrochloride
CAS 2241127-88-6C10H18ClNO2
4-Methyl-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-amine chemical structure, C10H17NO2, CAS 2241127-87-5
4-Methyl-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-amine
CAS 2241127-87-5C10H17NO2
tert-Butyl N-[4-(hydroxymethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-yl]carbamate chemical structure, C15H25NO5, CAS 2408958-33-6
tert-Butyl N-[4-(hydroxymethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-yl]carbamate
CAS 2408958-33-6C15H25NO5
Methyl 4-(aminomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylate chemical structure, C12H19NO4, CAS 2639421-46-6
Methyl 4-(aminomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylate
CAS 2639421-46-6C12H19NO4
tert-Butyl 4-(aminomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylate chemical structure, C15H25NO4, CAS 2639421-52-4
tert-Butyl 4-(aminomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylate
CAS 2639421-52-4C15H25NO4
4-(Aminomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-amine chemical structure, C10H18N2O2, CAS 2639405-59-5
4-(Aminomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-amine
CAS 2639405-59-5C10H18N2O2
4-(Acetamidomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylic acid chemical structure, C13H19NO5, CAS 2680779-99-9
4-(Acetamidomethyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylic acid
CAS 2680779-99-9C13H19NO5
4-[(2,2,2-Trifluoroacetamido)methyl]-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylic acid chemical structure, C13H16F3NO5, CAS 2680684-79-9
4-[(2,2,2-Trifluoroacetamido)methyl]-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylic acid
CAS 2680684-79-9C13H16F3NO5
4-({[(Prop-2-en-1-yloxy)carbonyl]amino}methyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylic acid chemical structure, C15H21NO6, CAS 2763983-83-9
4-({[(Prop-2-en-1-yloxy)carbonyl]amino}methyl)-3-oxaspiro[bicyclo[2.1.1]hexane-2,4'-oxane]-1-carboxylic acid
CAS 2763983-83-9C15H21NO6