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Murcko scaffold

Ring system with 5 rings and 26 atoms

8 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
26
Chemicals
8
With full pages
3
Scaffold SMILES

O=[PH]1OCC2OC(n3c(Sc4ccccc4)nc4cncnc43)CC2O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=[PH]1OCC2OC(n3c(Sc4ccccc4)nc4cncnc43)CC2O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

8-(4-Chlorophenylthio)-cAMP chemical structure, C16H15ClN5O6PS, CAS 41941-66-6
8-(4-Chlorophenylthio)-cAMP
CAS 41941-66-6C16H15ClN5O6PS
8-PCPT-2'-O-Me-cAMP chemical structure, C17H17ClN5O6PS, CAS 634207-53-7
8-PCPT-2'-O-Me-cAMP
CAS 634207-53-7C17H17ClN5O6PS
Orb2646143 chemical structure, C19H19ClN5O8PS, CAS 663941-66-0
Orb2646143
CAS 663941-66-0C19H19ClN5O8PS
9-[(4aR,6R,7R,7aR)-2-Hydroxy-7-methoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-8-(4-methoxyphenyl)sulfanylpurin-6-amine chemical structure, C18H20N5O7PS, CAS 612513-16-3
9-[(4aR,6R,7R,7aR)-2-Hydroxy-7-methoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-8-(4-methoxyphenyl)sulfanylpurin-6-amine
CAS 612513-16-3C18H20N5O7PS
4-[9-[(4aR,6R,7R,7aR)-2-Hydroxy-7-methoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-6-aminopurin-8-yl]sulfanylphenol chemical structure, C17H18N5O7PS, CAS 612513-15-2
4-[9-[(4aR,6R,7R,7aR)-2-Hydroxy-7-methoxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-6-aminopurin-8-yl]sulfanylphenol
CAS 612513-15-2C17H18N5O7PS
8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic Monophosphate sodium salt chemical structure, C17H16ClN5NaO6PS, CAS 510774-50-2
8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic Monophosphate sodium salt
CAS 510774-50-2C17H16ClN5NaO6PS
Sodium (4aR,6R,7R,7aS)-6-(6-amino-8-((4-chlorophenyl)thio)-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-D][1,3,2]dioxaphosphinin-2-olate 2-oxide chemical structure, C16H14ClN5NaO6PS, CAS 93882-12-3
Sodium (4aR,6R,7R,7aS)-6-(6-amino-8-((4-chlorophenyl)thio)-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-D][1,3,2]dioxaphosphinin-2-olate 2-oxide
CAS 93882-12-3C16H14ClN5NaO6PS
8-PCPT-2-O-Me-cAMP-AM chemical structure, C20H21ClN5O8PS, CAS 1152197-23-3
8-PCPT-2-O-Me-cAMP-AM
CAS 1152197-23-3C20H21ClN5O8PS