CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 26 atoms

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
27
With full pages
4
Scaffold SMILES

O=C(CCc1c[nH]c2ccccc12)NCC(=O)NCCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCc1c[nH]c2ccccc12)NCC(=O)NCCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

Trp-Lys-Tyr-Met-Val-D-Met chemical structure, C41H60N8O8S2, CAS 211868-45-0
Trp-Lys-Tyr-Met-Val-D-Met
CAS 211868-45-0C41H60N8O8S2
WKYMVm chemical structure, C41H61N9O7S2, CAS 187986-17-0
WKYMVm
CAS 187986-17-0C41H61N9O7S2
tert-Butyl N-[1-[[1-[(1-amino-1-oxo-3-phenylpropan-2-yl)amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamate chemical structure, C30H39N5O5S, CAS 104180-24-7
tert-Butyl N-[1-[[1-[(1-amino-1-oxo-3-phenylpropan-2-yl)amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]carbamate
CAS 104180-24-7C30H39N5O5S
L-Serine, L-tryptophyl-L-asparaginyl-L-tyrosyl-L-valyl- chemical structure, C32H41N7O9, CAS 398469-58-4
L-Serine, L-tryptophyl-L-asparaginyl-L-tyrosyl-L-valyl-
CAS 398469-58-4C32H41N7O9
H-Trp-Gly-Tyr-OH chemical structure, C22H24N4O5, CAS 15035-24-2
H-Trp-Gly-Tyr-OH
CAS 15035-24-2C22H24N4O5
Glu-Ile-Trp-Thr-Phe-Ser-Thr-Lys-Val chemical structure, C53H79N11O15, CAS 460039-30-9
Glu-Ile-Trp-Thr-Phe-Ser-Thr-Lys-Val
CAS 460039-30-9C53H79N11O15
Glycine, L-tryptophyl-L-lysyl-L-tyrosyl-L-methionyl-L-valyl- chemical structure, C38H54N8O8S, CAS 573691-84-6
Glycine, L-tryptophyl-L-lysyl-L-tyrosyl-L-methionyl-L-valyl-
CAS 573691-84-6C38H54N8O8S
L-Tyrosine, L-tryptophyl-L-arginyl- chemical structure, C26H33N7O5, CAS 160248-31-7
L-Tyrosine, L-tryptophyl-L-arginyl-
CAS 160248-31-7C26H33N7O5
L-Tyrosine, L-arginylglycyl-L-arginyl-L-seryl-L-tryptophyl-L-threonyl- chemical structure, C41H60N14O11, CAS 854181-93-4
L-Tyrosine, L-arginylglycyl-L-arginyl-L-seryl-L-tryptophyl-L-threonyl-
CAS 854181-93-4C41H60N14O11
L-Cysteine, L-leucyl-L-tryptophyl-L-alanyl-L-phenylalanyl-L-cysteinyl- chemical structure, C35H47N7O7S2, CAS 776303-78-7
L-Cysteine, L-leucyl-L-tryptophyl-L-alanyl-L-phenylalanyl-L-cysteinyl-
CAS 776303-78-7C35H47N7O7S2
L-Tryptophyl-L-valyl-L-tyrosyl-L-isoleucine chemical structure, C31H41N5O6, CAS 918661-83-3
L-Tryptophyl-L-valyl-L-tyrosyl-L-isoleucine
CAS 918661-83-3C31H41N5O6
HLA-DR.B. Peptide(141-155) chemical structure, C75H113N19O24, CAS 129437-47-4
HLA-DR.B. Peptide(141-155)
CAS 129437-47-4C75H113N19O24
L-Arginyl-2,5,7-tris(1,1-dimethylethyl)-L-tryptophyl-N-(2-phenylethyl)-L-argininamide chemical structure, C43H69N11O3, CAS 1166254-80-3
L-Arginyl-2,5,7-tris(1,1-dimethylethyl)-L-tryptophyl-N-(2-phenylethyl)-L-argininamide
CAS 1166254-80-3C43H69N11O3
Trp-Lys-Tyr-Met-Val-Met-NH2 chemical structure, C41H61N9O7S2, CAS 187986-11-4
Trp-Lys-Tyr-Met-Val-Met-NH2
CAS 187986-11-4C41H61N9O7S2
Wkymvm-NH2 (tfa) chemical structure, C43H62F3N9O9S2, CAS 1435781-74-0
Wkymvm-NH2 (tfa)
CAS 1435781-74-0C43H62F3N9O9S2
Wkymvm (tfa) chemical structure, C43H62F3N9O9S2, CAS 1313730-09-4
Wkymvm (tfa)
CAS 1313730-09-4C43H62F3N9O9S2
(S)-2-((S)-2-((S)-2-Amino-3-(1H-indol-3-yl)propanamido)-3-hydroxypropanamido)-3-phenylpropanoic acid chemical structure, C23H26N4O5, CAS 105394-87-4
(S)-2-((S)-2-((S)-2-Amino-3-(1H-indol-3-yl)propanamido)-3-hydroxypropanamido)-3-phenylpropanoic acid
CAS 105394-87-4C23H26N4O5
L-Cysteinylglycyl-L-seryl-L-cysteinyl-L-tryptophyl-L-alanyl-L-phenylalanine chemical structure, C34H44N8O9S2, CAS 348635-60-9
L-Cysteinylglycyl-L-seryl-L-cysteinyl-L-tryptophyl-L-alanyl-L-phenylalanine
CAS 348635-60-9C34H44N8O9S2
Trp-Lys-Tyr-Met-Val-Met chemical structure, C41H60N8O8S2, CAS 496068-62-3
Trp-Lys-Tyr-Met-Val-Met
CAS 496068-62-3C41H60N8O8S2
Glycyl-D-alanyl-D-tryptophyl-D-alanyl-D-tyrosine chemical structure, C28H34N6O7, CAS 644997-31-9
Glycyl-D-alanyl-D-tryptophyl-D-alanyl-D-tyrosine
CAS 644997-31-9C28H34N6O7
L-Valyl-L-tryptophyl-L-lysyl-L-phenylalanyl-L-glutaminyl-N~5~-(diaminomethylidene)-L-ornithine chemical structure, C42H62N12O8, CAS 630391-06-9
L-Valyl-L-tryptophyl-L-lysyl-L-phenylalanyl-L-glutaminyl-N~5~-(diaminomethylidene)-L-ornithine
CAS 630391-06-9C42H62N12O8
L-Tryptophyl-N~5~-(diaminomethylidene)-L-ornithyl-L-phenylalanyl-L-lysine chemical structure, C32H45N9O5, CAS 871205-62-8
L-Tryptophyl-N~5~-(diaminomethylidene)-L-ornithyl-L-phenylalanyl-L-lysine
CAS 871205-62-8C32H45N9O5
N-Acetyl-L-tryptophylglycyl-L-phenylalaninamide chemical structure, C24H27N5O4, CAS 132766-16-6
N-Acetyl-L-tryptophylglycyl-L-phenylalaninamide
CAS 132766-16-6C24H27N5O4
H-D-Trp-D-Met-p-chloro-D-Phe-Gla-NH2 chemical structure, C31H37ClN6O8S, CAS 178396-45-7
H-D-Trp-D-Met-p-chloro-D-Phe-Gla-NH2
CAS 178396-45-7C31H37ClN6O8S