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Murcko scaffold

Ring system with 3 rings and 18 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
19
With full pages
2
Scaffold SMILES

c1ccc(N2CCCC2)c(CN2CCNCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(N2CCCC2)c(CN2CCNCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

Elcubragistat chemical structure, C20H22F9N3O2, CAS 1446817-84-0
Elcubragistat
CAS 1446817-84-0C20H22F9N3O2
1,1,1,3,3,3-Hexafluoropropan-2-yl 4-(3-chloro-2-(pyrrolidin-1-yl)benzyl)piperazine-1-carboxylate chemical structure, C19H22ClF6N3O2, CAS 1446817-85-1
1,1,1,3,3,3-Hexafluoropropan-2-yl 4-(3-chloro-2-(pyrrolidin-1-yl)benzyl)piperazine-1-carboxylate
CAS 1446817-85-1C19H22ClF6N3O2
tert-Butyl 4-[[5-chloro-2-(pyrrolidin-1-yl)phenyl]methyl]piperazine-1-carboxylate chemical structure, C20H30ClN3O2, CAS 1446818-74-1
tert-Butyl 4-[[5-chloro-2-(pyrrolidin-1-yl)phenyl]methyl]piperazine-1-carboxylate
CAS 1446818-74-1C20H30ClN3O2
1-[[5-Chloro-2-(pyrrolidin-1-yl)phenyl]methyl]piperazine chemical structure, C15H22ClN3, CAS 1446818-75-2
1-[[5-Chloro-2-(pyrrolidin-1-yl)phenyl]methyl]piperazine
CAS 1446818-75-2C15H22ClN3
tert-Butyl 4-[[2-chloro-6-(pyrrolidin-1-yl)phenyl]methyl]piperazine-1-carboxylate chemical structure, C20H30ClN3O2, CAS 1446818-71-8
tert-Butyl 4-[[2-chloro-6-(pyrrolidin-1-yl)phenyl]methyl]piperazine-1-carboxylate
CAS 1446818-71-8C20H30ClN3O2
tert-Butyl 4-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine-1-carboxylate chemical structure, C21H30F3N3O2, CAS 1446819-16-4
tert-Butyl 4-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine-1-carboxylate
CAS 1446819-16-4C21H30F3N3O2
tert-Butyl 4-(4-bromo-2-(pyrrolidin-1-yl)benzyl)piperazine-1-carboxylate chemical structure, C20H30BrN3O2, CAS 1446818-83-2
tert-Butyl 4-(4-bromo-2-(pyrrolidin-1-yl)benzyl)piperazine-1-carboxylate
CAS 1446818-83-2C20H30BrN3O2
1-(4-Bromo-2-(pyrrolidin-1-yl)benzyl)piperazine chemical structure, C15H22BrN3, CAS 3078410-48-4
1-(4-Bromo-2-(pyrrolidin-1-yl)benzyl)piperazine
CAS 3078410-48-4C15H22BrN3
1-(2-(Pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine chemical structure, C16H22F3N3, CAS 1446819-17-5
1-(2-(Pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine
CAS 1446819-17-5C16H22F3N3
1-[[2-Chloro-6-(pyrrolidin-1-yl)phenyl]methyl]piperazine chemical structure, C15H22ClN3, CAS 1446818-72-9
1-[[2-Chloro-6-(pyrrolidin-1-yl)phenyl]methyl]piperazine
CAS 1446818-72-9C15H22ClN3
tert-Butyl 4-[[5-methyl-2-(pyrrolidin-1-yl)phenyl]methyl]piperazine-1-carboxylate chemical structure, C21H33N3O2, CAS 1460033-53-7
tert-Butyl 4-[[5-methyl-2-(pyrrolidin-1-yl)phenyl]methyl]piperazine-1-carboxylate
CAS 1460033-53-7C21H33N3O2
1-[[5-Methyl-2-(pyrrolidin-1-yl)phenyl]methyl]piperazine chemical structure, C16H25N3, CAS 1460033-56-0
1-[[5-Methyl-2-(pyrrolidin-1-yl)phenyl]methyl]piperazine
CAS 1460033-56-0C16H25N3
1,1,1,3,3,3-Hexafluoropropan-2-yl 4-((2-pyrrolidin-1-yl-4-(trifluoromethyl)phenyl)methyl)piperazine-1-carboxylate, hydrochloride chemical structure, C20H23ClF9N3O2, CAS 2043074-64-0
1,1,1,3,3,3-Hexafluoropropan-2-yl 4-((2-pyrrolidin-1-yl-4-(trifluoromethyl)phenyl)methyl)piperazine-1-carboxylate, hydrochloride
CAS 2043074-64-0C20H23ClF9N3O2
1-(4-Bromo-2-(pyrrolidin-1-yl)benzyl)-4-methylpiperazine chemical structure, C16H24BrN3, CAS 3078392-86-3
1-(4-Bromo-2-(pyrrolidin-1-yl)benzyl)-4-methylpiperazine
CAS 3078392-86-3C16H24BrN3
1-(4-Bromo-2-(pyrrolidin-1-yl)benzyl)-4-ethylpiperazine chemical structure, C17H26BrN3, CAS 3078406-44-4
1-(4-Bromo-2-(pyrrolidin-1-yl)benzyl)-4-ethylpiperazine
CAS 3078406-44-4C17H26BrN3
1-(4-Bromo-2-(pyrrolidin-1-yl)benzyl)-4-isopropylpiperazine chemical structure, C18H28BrN3, CAS 3078410-45-1
1-(4-Bromo-2-(pyrrolidin-1-yl)benzyl)-4-isopropylpiperazine
CAS 3078410-45-1C18H28BrN3
1-(4-Bromo-2-(pyrrolidin-1-yl)benzyl)-4-(2,2,2-trifluoroethyl)piperazine chemical structure, C17H23BrF3N3, CAS 3078396-95-6
1-(4-Bromo-2-(pyrrolidin-1-yl)benzyl)-4-(2,2,2-trifluoroethyl)piperazine
CAS 3078396-95-6C17H23BrF3N3
tert-Butyl 4-(4-bromo-2-(pyrrolidin-1-yl)benzyl)-2-methylpiperazine-1-carboxylate chemical structure, C21H32BrN3O2, CAS 3078410-51-9
tert-Butyl 4-(4-bromo-2-(pyrrolidin-1-yl)benzyl)-2-methylpiperazine-1-carboxylate
CAS 3078410-51-9C21H32BrN3O2
tert-Butyl 4-(4-bromo-2-(pyrrolidin-1-yl)benzyl)-3-methylpiperazine-1-carboxylate chemical structure, C21H32BrN3O2, CAS 3078392-89-6
tert-Butyl 4-(4-bromo-2-(pyrrolidin-1-yl)benzyl)-3-methylpiperazine-1-carboxylate
CAS 3078392-89-6C21H32BrN3O2