Murcko scaffold
Ring system with 5 rings and 27 atoms
19 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 27
- Chemicals
- 19
- With full pages
- 1
Scaffold SMILES
O=c1c(-c2nc3ccccc3s2)coc2c(CN3CCCCC3)cccc12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 19 of 19 chemicals
3-(1,3-Benzothiazol-2-yl)-6-ethyl-7-hydroxy-8-((piperidin-1-yl)methyl)-4H-chromen-4-one
CAS 222716-34-9C24H24N2O3S
![3-(Benzo[d]thiazol-2-yl)-6-ethyl-7-hydroxy-8-((4-methylpiperidin-1-yl)methyl)-4H-chromen-4-one chemical structure, C25H26N2O3S, CAS 637747-17-2](/s/RWDGAMWASPIMGS-UHFFFAOYSA-N.svg)
3-(Benzo[d]thiazol-2-yl)-6-ethyl-7-hydroxy-8-((4-methylpiperidin-1-yl)methyl)-4H-chromen-4-one
CAS 637747-17-2C25H26N2O3S
![3-(Benzo[d]thiazol-2-yl)-8-((3,3-dimethylpiperidin-1-yl)methyl)-6-ethyl-7-hydroxy-4H-chromen-4-one chemical structure, C26H28N2O3S, CAS 637747-37-6](/s/KPEBBTIKYOWPML-UHFFFAOYSA-N.svg)
3-(Benzo[d]thiazol-2-yl)-8-((3,3-dimethylpiperidin-1-yl)methyl)-6-ethyl-7-hydroxy-4H-chromen-4-one
CAS 637747-37-6C26H28N2O3S
![Ethyl 3-(benzo[d]thiazol-2-yl)-6-ethyl-7-hydroxy-4-oxo-8-(piperidin-1-ylmethyl)-4H-chromene-2-carboxylate chemical structure, C27H28N2O5S, CAS 433700-24-4](/s/FBZAXVOFLUKLIK-UHFFFAOYSA-N.svg)
Ethyl 3-(benzo[d]thiazol-2-yl)-6-ethyl-7-hydroxy-4-oxo-8-(piperidin-1-ylmethyl)-4H-chromene-2-carboxylate
CAS 433700-24-4C27H28N2O5S
3-(1,3-Benzothiazol-2-yl)-6-ethyl-7-hydroxy-2-methyl-8-(piperidin-1-ylmethyl)-4H-chromen-4-one
CAS 222716-44-1C25H26N2O3S
![3-(Benzo[d]thiazol-2-yl)-6-ethyl-7-hydroxy-8-((3-methylpiperidin-1-yl)methyl)-4H-chromen-4-one chemical structure, C25H26N2O3S, CAS 637747-22-9](/s/GPGRJNRGDXNHRD-UHFFFAOYSA-N.svg)
3-(Benzo[d]thiazol-2-yl)-6-ethyl-7-hydroxy-8-((3-methylpiperidin-1-yl)methyl)-4H-chromen-4-one
CAS 637747-22-9C25H26N2O3S
![3-(Benzo[d]thiazol-2-yl)-8-((2,6-dimethylpiperidin-1-yl)methyl)-6-ethyl-7-hydroxy-4H-chromen-4-one chemical structure, C26H28N2O3S, CAS 637747-25-2](/s/FIQZJFNKDJRREJ-UHFFFAOYSA-N.svg)
3-(Benzo[d]thiazol-2-yl)-8-((2,6-dimethylpiperidin-1-yl)methyl)-6-ethyl-7-hydroxy-4H-chromen-4-one
CAS 637747-25-2C26H28N2O3S
![3-(Benzo[d]thiazol-2-yl)-6-ethyl-7-hydroxy-8-((2-methylpiperidin-1-yl)methyl)-4H-chromen-4-one chemical structure, C25H26N2O3S, CAS 637747-34-3](/s/ZNAPBJMDFYLPRS-UHFFFAOYSA-N.svg)
3-(Benzo[d]thiazol-2-yl)-6-ethyl-7-hydroxy-8-((2-methylpiperidin-1-yl)methyl)-4H-chromen-4-one
CAS 637747-34-3C25H26N2O3S
![3-(1,3-Benzothiazol-2-yl)-7-hydroxy-2-methyl-8-[(4-methylpiperidin-1-yl)methyl]-4H-chromen-4-one chemical structure, C24H24N2O3S, CAS 308297-84-9](/s/FUTJYHVXSCCQDJ-UHFFFAOYSA-N.svg)
3-(1,3-Benzothiazol-2-yl)-7-hydroxy-2-methyl-8-[(4-methylpiperidin-1-yl)methyl]-4H-chromen-4-one
CAS 308297-84-9C24H24N2O3S
![3-(Benzo[d]thiazol-2-yl)-7-hydroxy-8-(piperidin-1-ylmethyl)-4H-chromen-4-one chemical structure, C22H20N2O3S, CAS 314745-62-5](/s/RHLLQZYAULWSJE-UHFFFAOYSA-N.svg)
3-(Benzo[d]thiazol-2-yl)-7-hydroxy-8-(piperidin-1-ylmethyl)-4H-chromen-4-one
CAS 314745-62-5C22H20N2O3S
![3-(Benzo[d]thiazol-2-yl)-7-hydroxy-8-((4-methylpiperidin-1-yl)methyl)-4H-chromen-4-one chemical structure, C23H22N2O3S, CAS 637747-58-1](/s/ATCMOHWSWARZAW-UHFFFAOYSA-N.svg)
3-(Benzo[d]thiazol-2-yl)-7-hydroxy-8-((4-methylpiperidin-1-yl)methyl)-4H-chromen-4-one
CAS 637747-58-1C23H22N2O3S
![3-(1,3-Benzothiazol-2-yl)-7-hydroxy-2-methyl-8-[(2-methylpiperidin-1-yl)methyl]-4H-chromen-4-one chemical structure, C24H24N2O3S, CAS 308297-82-7](/s/GTULVKNEFCCPIH-UHFFFAOYSA-N.svg)
3-(1,3-Benzothiazol-2-yl)-7-hydroxy-2-methyl-8-[(2-methylpiperidin-1-yl)methyl]-4H-chromen-4-one
CAS 308297-82-7C24H24N2O3S
![3-(Benzo[d]thiazol-2-yl)-7-hydroxy-2-methyl-8-((3-methylpiperidin-1-yl)methyl)-4H-chromen-4-one chemical structure, C24H24N2O3S, CAS 308297-83-8](/s/CXOCDNMWNQVADN-UHFFFAOYSA-N.svg)
3-(Benzo[d]thiazol-2-yl)-7-hydroxy-2-methyl-8-((3-methylpiperidin-1-yl)methyl)-4H-chromen-4-one
CAS 308297-83-8C24H24N2O3S
![2-Amino-3-(1,3-benzothiazol-2-yl)-7-hydroxy-8-[(3-methyl-1-piperidinyl)methyl]-4H-chromen-4-one chemical structure, C23H23N3O3S, CAS 610759-75-6](/s/DODVOGUYLCMAHP-UHFFFAOYSA-N.svg)
2-Amino-3-(1,3-benzothiazol-2-yl)-7-hydroxy-8-[(3-methyl-1-piperidinyl)methyl]-4H-chromen-4-one
CAS 610759-75-6C23H23N3O3S
![2-Amino-3-(benzo[d]thiazol-2-yl)-8-((3,3-dimethylpiperidin-1-yl)methyl)-7-hydroxy-4H-chromen-4-one chemical structure, C24H25N3O3S, CAS 610759-84-7](/s/QCJMYFCZFFUWDZ-UHFFFAOYSA-N.svg)
2-Amino-3-(benzo[d]thiazol-2-yl)-8-((3,3-dimethylpiperidin-1-yl)methyl)-7-hydroxy-4H-chromen-4-one
CAS 610759-84-7C24H25N3O3S
![3-(Benzo[d]thiazol-2-yl)-8-((2-ethylpiperidin-1-yl)methyl)-7-hydroxy-4H-chromen-4-one chemical structure, C24H24N2O3S, CAS 637747-56-9](/s/BJYPTCSTEWHGCQ-UHFFFAOYSA-N.svg)
3-(Benzo[d]thiazol-2-yl)-8-((2-ethylpiperidin-1-yl)methyl)-7-hydroxy-4H-chromen-4-one
CAS 637747-56-9C24H24N2O3S
2-Amino-3-benzothiazol-2-yl-7-hydroxy-8-(2-methyl-piperidin-1-ylmethyl)-chromen-4-one
CAS 610759-76-7C23H23N3O3S
3-Benzothiazol-2-yl-7-hydroxy-8-(2-methyl-piperidin-1-ylmethyl)-chromen-4-one
CAS 637747-57-0C23H22N2O3S
![3-(1,3-Benzothiazol-2-yl)-7-hydroxy-8-[(3-methylpiperidin-1-yl)methyl]-4H-chromen-4-one chemical structure, C23H22N2O3S, CAS 637747-63-8](/s/WFRSFJHNRAQMBY-UHFFFAOYSA-N.svg)
3-(1,3-Benzothiazol-2-yl)-7-hydroxy-8-[(3-methylpiperidin-1-yl)methyl]-4H-chromen-4-one
CAS 637747-63-8C23H22N2O3S