Murcko scaffold
3-[(1,3-Benzodioxol-5-yloxi)methyl-]4-phenyl-piperidine scaffold
40 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 23
- Chemicals
- 40
- With full pages
- 14
Scaffold SMILES
c1ccc(C2CCNCC2COc2ccc3c(c2)OCO3)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 40 of 40 chemicals
3-(1,3-Benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine
CAS 72473-26-8C19H20FNO3
Paroxetine
CAS 61869-08-7C19H20FNO3
Paroxetine hydrochloride
CAS 78246-49-8C19H21ClFNO3
N-(3-Fluoropropyl)paroxetine
CAS 138135-14-5C22H25F2NO3
Paroxetine, (+)-
CAS 112058-85-2C19H20FNO3
Paroxetine, cis-(-)-
CAS 105813-07-8C19H20FNO3
Paroxetine, cis-(+)-
CAS 105813-05-6C19H20FNO3
Desfluoroparoxetine
CAS 324024-00-2C19H21NO3
Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-1-methyl-4-phenyl-, hydrochloride, cis-(-)-
CAS 54088-16-3C20H24ClNO3
Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-phenyl-, hydrochloride, cis-(-)-
CAS 54088-36-7C19H22ClNO3
Paroxetine hydrochloride hemihydrate
CAS 110429-35-1C38H44Cl2F2N2O7
Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-, (3S,4R)-, (2Z)-2-butenedioate (1:1)
CAS 64006-44-6C23H24FNO7
Paroxetine acetate
CAS 72471-80-8C21H24FNO5
Paroxetine hydrochloride acetone solvate
CAS 181237-74-1C22H27ClFNO4
![Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrobromide (1:1), (3S,4R)- chemical structure, C19H21BrFNO3, CAS 121368-57-8](/s/NEFIGJLRLGOCSQ-RVXRQPKJSA-N.svg)
Piperidine, 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrobromide (1:1), (3S,4R)-
CAS 121368-57-8C19H21BrFNO3
Paroxetine mesylate
CAS 217797-14-3C20H24FNO6S
![3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine hydrochloride chemical structure, C19H21ClFNO3, CAS 1193389-61-5](/s/GELRVIPPMNMYGS-UHFFFAOYSA-N.svg)
3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine hydrochloride
CAS 1193389-61-5C19H21ClFNO3
Paroxetine impurity 27
CAS 2575750-19-3C20H22FNO3
N-Methylparoxetine
CAS 110429-36-2C20H22FNO3
Paroxetine hydrochloride anhydrous, cis-
CAS 105813-04-5C19H21ClFNO3
ent-Paroxetine Hydrochloride
CAS 130855-30-0C19H21ClFNO3
Paroxetine hydrochloride impurity 50
C20H23NO4
Paroxetine HCl HeMihydrate IMpurity B HCl
C20H23NO4
![3-[(1,3-Benzodioxol-5-yloxi)methyl-]4-phenyl-piperidine chemical structure, C19H21NO3](/s/VUYNWBMXOQBJAI-UHFFFAOYSA-N.svg)
3-[(1,3-Benzodioxol-5-yloxi)methyl-]4-phenyl-piperidine
C19H21NO3
- (3S,4R)-3-(((Benzo[d][1,3]dioxol-5-yl-2,2-d2)oxy)methyl)-4-(4-fluorophenyl)-1-methylpiperidine936838-88-9C20H22FNO3
- rac trans-Paroxetine-d4 Hydrochloride1217753-24-6C19H21ClFNO3
- 4-(3'-Methoxybenzoyl)-N,N-diethylbenzamide1322626-23-2C19H21NO3
- Piperidine, 3-[(1,3-benzodioxol-5-yl-2,2-d2-oxy)methyl]-4-(4-fluorophenyl)-, (3S,4R)-923932-43-8C19H20FNO3
- trans-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-methoxyphenyl)-1-methylpiperidine127017-42-9C21H25NO4
- 9Sqg6tgd98127017-69-0C20H23NO4
- rac cis-Paroxetine Hydrochloride105813-03-4C19H21ClFNO3
- rac-trans-4-Defluoro-4-ethoxy Paroxetine Hydrochloride1346597-97-4C21H26ClNO4
- (3S,4R)-3-[(1,3-Dioxaindan-5-yloxy)methyl]-4-(4-ethoxyphenyl)piperidine1395408-54-4C21H25NO4
- 1 suppliersrac-trans-4-Defluoro-4-methoxy Paroxetine Hydrochloride127017-74-7C20H24ClNO4
- Paroxetine-d61435728-63-4C19H20FNO3
- rac-Paroxetine-d4 Hydrochloride1217683-35-6C19H21ClFNO3
- Paroxetine-d41217976-29-8C19H20FNO3
- Defluoro paroxetine hydrochloride1394842-91-1C19H22ClNO3
- (3R,4R)-tert-Butyl 3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine-1-carboxylate1622258-77-8C24H28FNO5
- N-Nitroso paroxetine2361294-43-9C19H19FN2O4
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=C1CC(c2ccccc2)C(C(=O)Nc2ccc3[nH]ncc3c2)=CN1](/scaffold/RMKGHVHYUXVUAO-UHFFFAOYSA-N/structure.svg)
![Scaffold O=C1NC=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccccc2)N1](/scaffold/VTKASQDEBREUHH-UHFFFAOYSA-N/structure.svg)