CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 21 atoms

4 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
4
With full pages
1
Scaffold SMILES

O=C(Nc1ccccc1)c1ccnn1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccnn1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

N-(2-Chlorophenyl)-3-(1,1-dimethylethyl)-1-[(4-fluorophenyl)methyl]-1H-pyrazole-5-carboxamide chemical structure, C21H21ClFN3O, CAS 959583-53-0
N-(2-Chlorophenyl)-3-(1,1-dimethylethyl)-1-[(4-fluorophenyl)methyl]-1H-pyrazole-5-carboxamide
CAS 959583-53-0C21H21ClFN3O
N-(4-Chlorophenyl)-3-(1,1-dimethylethyl)-1-[(2,4,6-trimethylphenyl)methyl]-1H-pyrazole-5-carboxamide chemical structure, C24H28ClN3O, CAS 959578-05-3
N-(4-Chlorophenyl)-3-(1,1-dimethylethyl)-1-[(2,4,6-trimethylphenyl)methyl]-1H-pyrazole-5-carboxamide
CAS 959578-05-3C24H28ClN3O
Cfm-1571 chemical structure, C23H28N4O3, CAS 268725-86-6
Cfm-1571
CAS 268725-86-6C23H28N4O3
Cfm 1571 hydrochloride chemical structure, C23H29ClN4O3, CAS 1215548-30-3
Cfm 1571 hydrochloride
CAS 1215548-30-3C23H29ClN4O3