CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 22 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
8
With full pages
6
Scaffold SMILES

O=C(Nc1cccc(NC(=O)c2cccs2)c1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cccc(NC(=O)c2cccs2)c1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

N-{2-Methyl-5-[(2-thienylcarbonyl)amino]phenyl}-2-thiophenecarboxamide chemical structure, C17H14N2O2S2, CAS 332859-80-0
N-{2-Methyl-5-[(2-thienylcarbonyl)amino]phenyl}-2-thiophenecarboxamide
CAS 332859-80-0C17H14N2O2S2
N-[2-Methyl-3-(thiophene-2-carbonylamino)phenyl]thiophene-2-carboxamide chemical structure, C17H14N2O2S2, CAS 355001-95-5
N-[2-Methyl-3-(thiophene-2-carbonylamino)phenyl]thiophene-2-carboxamide
CAS 355001-95-5C17H14N2O2S2
N-[2,4,6-Trimethyl-3-(thiophene-2-carbonylamino)phenyl]thiophene-2-carboxamide chemical structure, C19H18N2O2S2, CAS 312317-44-5
N-[2,4,6-Trimethyl-3-(thiophene-2-carbonylamino)phenyl]thiophene-2-carboxamide
CAS 312317-44-5C19H18N2O2S2
3,5-Bis-[(thiophene-2-carbonyl)-amino]-benzoic acid chemical structure, C17H12N2O4S2, CAS 25700-68-9
3,5-Bis-[(thiophene-2-carbonyl)-amino]-benzoic acid
CAS 25700-68-9C17H12N2O4S2
N-[2-Nitro-5-(thiophene-2-carbonylamino)phenyl]thiophene-2-carboxamide chemical structure, C16H11N3O4S2, CAS 5245-72-7
N-[2-Nitro-5-(thiophene-2-carbonylamino)phenyl]thiophene-2-carboxamide
CAS 5245-72-7C16H11N3O4S2
N-[3-(tert-Butylcarbamoyl)-5-(thiophene-2-carbonylamino)phenyl]thiophene-2-carboxamide chemical structure, C21H21N3O3S2, CAS 355403-33-7
N-[3-(tert-Butylcarbamoyl)-5-(thiophene-2-carbonylamino)phenyl]thiophene-2-carboxamide
CAS 355403-33-7C21H21N3O3S2
5-Bromo-N-[3-[(5-bromothiophene-2-carbonyl)amino]phenyl]thiophene-2-carboxamide chemical structure, C16H10Br2N2O2S2, CAS 476357-02-5
5-Bromo-N-[3-[(5-bromothiophene-2-carbonyl)amino]phenyl]thiophene-2-carboxamide
CAS 476357-02-5C16H10Br2N2O2S2
5-Chloro-N-[3-[(5-chlorothiophene-2-carbonyl)amino]phenyl]thiophene-2-carboxamide chemical structure, C16H10Cl2N2O2S2, CAS 476357-03-6
5-Chloro-N-[3-[(5-chlorothiophene-2-carbonyl)amino]phenyl]thiophene-2-carboxamide
CAS 476357-03-6C16H10Cl2N2O2S2