CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 9 atoms

34 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
9
Chemicals
34
With full pages
4
Scaffold SMILES

C1CC2(C1)OCC1CC12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1CC2(C1)OCC1CC12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

rac-(1R,5R)-3-Oxaspiro(bicyclo(3.1.0)hexane-2,1'-cyclobutane)-1-carboxylic acid chemical structure, C9H12O3, CAS 2137986-97-9
rac-(1R,5R)-3-Oxaspiro(bicyclo(3.1.0)hexane-2,1'-cyclobutane)-1-carboxylic acid
CAS 2137986-97-9C9H12O3
rac-(1R,5R)-3-Oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutane]-1-amine chemical structure, C8H13NO, CAS 2137593-03-2
rac-(1R,5R)-3-Oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutane]-1-amine
CAS 2137593-03-2C8H13NO
[(1S,5R)-Spiro[3-oxabicyclo[3.1.0]hexane-2,1'-cyclobutane]-1-yl]methanamine chemical structure, C9H15NO, CAS 2137629-40-2
[(1S,5R)-Spiro[3-oxabicyclo[3.1.0]hexane-2,1'-cyclobutane]-1-yl]methanamine
CAS 2137629-40-2C9H15NO
rac-[(1R,5R)-3-Oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutane]-1-yl]methanesulfonyl chloride chemical structure, C9H13ClO3S, CAS 2307758-08-1
rac-[(1R,5R)-3-Oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutane]-1-yl]methanesulfonyl chloride
CAS 2307758-08-1C9H13ClO3S
(3-Oxaspiro(bicyclo(3.1.0)hexane-2,1'-cyclobutane)-1-yl)methanol chemical structure, C9H14O2, CAS 2166932-74-5
(3-Oxaspiro(bicyclo(3.1.0)hexane-2,1'-cyclobutane)-1-yl)methanol
CAS 2166932-74-5C9H14O2
(1R,5R)-1-(Bromomethyl)spiro[3-oxabicyclo[3.1.0]hexane-2,1'-cyclobutane] chemical structure, C9H13BrO, CAS 2187426-60-2
(1R,5R)-1-(Bromomethyl)spiro[3-oxabicyclo[3.1.0]hexane-2,1'-cyclobutane]
CAS 2187426-60-2C9H13BrO
N-[[(1S,5R)-Spiro[3-oxabicyclo[3.1.0]hexane-2,1'-cyclobutane]-1-yl]methyl]prop-2-enamide chemical structure, C12H17NO2, CAS 2305176-62-7
N-[[(1S,5R)-Spiro[3-oxabicyclo[3.1.0]hexane-2,1'-cyclobutane]-1-yl]methyl]prop-2-enamide
CAS 2305176-62-7C12H17NO2
2-Chloro-N-[(1R,5R)-spiro[3-oxabicyclo[3.1.0]hexane-2,1'-cyclobutane]-1-yl]acetamide chemical structure, C10H14ClNO2, CAS 2411181-21-8
2-Chloro-N-[(1R,5R)-spiro[3-oxabicyclo[3.1.0]hexane-2,1'-cyclobutane]-1-yl]acetamide
CAS 2411181-21-8C10H14ClNO2
2-Chloro-N-({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)acetamide chemical structure, C11H16ClNO2, CAS 2137784-03-1
2-Chloro-N-({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)acetamide
CAS 2137784-03-1C11H16ClNO2
2-Methoxy-N-({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)acetamide chemical structure, C12H19NO3, CAS 2137757-60-7
2-Methoxy-N-({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)acetamide
CAS 2137757-60-7C12H19NO3
2-Bromo-N-({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)acetamide chemical structure, C11H16BrNO2, CAS 2137950-83-3
2-Bromo-N-({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)acetamide
CAS 2137950-83-3C11H16BrNO2
3-Chloro-N-({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)propanamide chemical structure, C12H18ClNO2, CAS 2138249-33-7
3-Chloro-N-({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)propanamide
CAS 2138249-33-7C12H18ClNO2
2-Chloro-N-({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)propanamide chemical structure, C12H18ClNO2, CAS 2137658-74-1
2-Chloro-N-({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)propanamide
CAS 2137658-74-1C12H18ClNO2
3-[({3-Oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)carbamoyl]propanoic acid chemical structure, C13H19NO4, CAS 2137866-17-0
3-[({3-Oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)carbamoyl]propanoic acid
CAS 2137866-17-0C13H19NO4
Ethyl 2-[({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)carbamoyl]acetate chemical structure, C14H21NO4, CAS 2137714-43-1
Ethyl 2-[({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)carbamoyl]acetate
CAS 2137714-43-1C14H21NO4
Ethyl 3-[({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)carbamoyl]propanoate chemical structure, C15H23NO4, CAS 2137701-02-9
Ethyl 3-[({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)carbamoyl]propanoate
CAS 2137701-02-9C15H23NO4
Methyl [({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)carbamoyl]formate chemical structure, C12H17NO4, CAS 2138252-58-9
Methyl [({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)carbamoyl]formate
CAS 2138252-58-9C12H17NO4
5-Chloro-N-({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)pentanamide chemical structure, C14H22ClNO2, CAS 2138252-62-5
5-Chloro-N-({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)pentanamide
CAS 2138252-62-5C14H22ClNO2
3-Chloro-2,2-dimethyl-N-({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)propanamide chemical structure, C14H22ClNO2, CAS 2137600-68-9
3-Chloro-2,2-dimethyl-N-({3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methyl)propanamide
CAS 2137600-68-9C14H22ClNO2
{3',3'-Dimethyl-3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methanol chemical structure, C11H18O2, CAS 2172533-92-3
{3',3'-Dimethyl-3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methanol
CAS 2172533-92-3C11H18O2
{3-Oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutane]-1-yl}methanesulfonyl chloride chemical structure, C9H13ClO3S, CAS 2166936-35-0
{3-Oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutane]-1-yl}methanesulfonyl chloride
CAS 2166936-35-0C9H13ClO3S
1-(Bromomethyl)-3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutane] chemical structure, C9H13BrO, CAS 2166942-28-3
1-(Bromomethyl)-3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutane]
CAS 2166942-28-3C9H13BrO
{3',3'-Dimethyl-3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methanesulfonyl chloride chemical structure, C11H17ClO3S, CAS 2171987-01-0
{3',3'-Dimethyl-3-oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutan]-1-yl}methanesulfonyl chloride
CAS 2171987-01-0C11H17ClO3S
3-Oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutane]-1-ylmethanesulfonamide chemical structure, C9H15NO3S, CAS 2227693-32-3
3-Oxaspiro[bicyclo[3.1.0]hexane-2,1'-cyclobutane]-1-ylmethanesulfonamide
CAS 2227693-32-3C9H15NO3S