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Murcko scaffold

Ring system with 4 rings and 33 atoms

48 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
33
Chemicals
48
With full pages
43
Scaffold SMILES

O=C(NN=Cc1c(OC(=O)c2ccccc2)ccc2ccccc12)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1c(OC(=O)c2ccccc2)ccc2ccccc12)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

1-(2-((4-Chloroanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 2,4-dichlorobenzoate chemical structure, C26H16Cl3N3O4, CAS 765274-00-8
1-(2-((4-Chloroanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 2,4-dichlorobenzoate
CAS 765274-00-8C26H16Cl3N3O4
1-(2-(Oxo(4-toluidino)acetyl)carbohydrazonoyl)-2-naphthyl 4-methylbenzoate chemical structure, C28H23N3O4, CAS 769153-69-7
1-(2-(Oxo(4-toluidino)acetyl)carbohydrazonoyl)-2-naphthyl 4-methylbenzoate
CAS 769153-69-7C28H23N3O4
1-(2-((3-Methoxyanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 4-chlorobenzoate chemical structure, C27H20ClN3O5, CAS 769147-31-1
1-(2-((3-Methoxyanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 4-chlorobenzoate
CAS 769147-31-1C27H20ClN3O5
1-(2-((4-Methoxyanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 4-methoxybenzoate chemical structure, C28H23N3O6, CAS 769148-84-7
1-(2-((4-Methoxyanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 4-methoxybenzoate
CAS 769148-84-7C28H23N3O6
1-(2-(Anilino(oxo)acetyl)carbohydrazonoyl)-2-naphthyl 2-chlorobenzoate chemical structure, C26H18ClN3O4, CAS 769156-34-5
1-(2-(Anilino(oxo)acetyl)carbohydrazonoyl)-2-naphthyl 2-chlorobenzoate
CAS 769156-34-5C26H18ClN3O4
1-(2-(Anilino(oxo)acetyl)carbohydrazonoyl)-2-naphthyl 4-methylbenzoate chemical structure, C27H21N3O4, CAS 769156-91-4
1-(2-(Anilino(oxo)acetyl)carbohydrazonoyl)-2-naphthyl 4-methylbenzoate
CAS 769156-91-4C27H21N3O4
1-(2-((4-Ethoxyanilino)(oxo)acetyl)carbohydrazonoyl)-2-naphthyl 4-methylbenzoate chemical structure, C29H25N3O5, CAS 767335-92-2
1-(2-((4-Ethoxyanilino)(oxo)acetyl)carbohydrazonoyl)-2-naphthyl 4-methylbenzoate
CAS 767335-92-2C29H25N3O5
1-(2-((4-Ethylanilino)(oxo)acetyl)carbohydrazonoyl)-2-naphthyl 4-chlorobenzoate chemical structure, C28H22ClN3O4, CAS 769153-33-5
1-(2-((4-Ethylanilino)(oxo)acetyl)carbohydrazonoyl)-2-naphthyl 4-chlorobenzoate
CAS 769153-33-5C28H22ClN3O4
1-(2-((4-Methoxyanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 4-methylbenzoate chemical structure, C28H23N3O5, CAS 769157-27-9
1-(2-((4-Methoxyanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 4-methylbenzoate
CAS 769157-27-9C28H23N3O5
1-(2-((4-Bromoanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 3,4-dimethoxybenzoate chemical structure, C28H22BrN3O6, CAS 765305-16-6
1-(2-((4-Bromoanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 3,4-dimethoxybenzoate
CAS 765305-16-6C28H22BrN3O6
1-((E)-{2-[2-Oxo-2-(4-toluidino)acetyl]hydrazono}methyl)-2-naphthyl 2,4-dichlorobenzoate chemical structure, C27H19Cl2N3O4, CAS 769152-68-3
1-((E)-{2-[2-Oxo-2-(4-toluidino)acetyl]hydrazono}methyl)-2-naphthyl 2,4-dichlorobenzoate
CAS 769152-68-3C27H19Cl2N3O4
1-(2-(Oxo(4-toluidino)acetyl)carbohydrazonoyl)-2-naphthyl 3-methylbenzoate chemical structure, C28H23N3O4, CAS 769152-33-2
1-(2-(Oxo(4-toluidino)acetyl)carbohydrazonoyl)-2-naphthyl 3-methylbenzoate
CAS 769152-33-2C28H23N3O4
1-(2-((4-Methoxyanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 3-methylbenzoate chemical structure, C28H23N3O5, CAS 769147-85-5
1-(2-((4-Methoxyanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 3-methylbenzoate
CAS 769147-85-5C28H23N3O5
1-(2-(Oxo(4-toluidino)acetyl)carbohydrazonoyl)-2-naphthyl 4-chlorobenzoate chemical structure, C27H20ClN3O4, CAS 769153-05-1
1-(2-(Oxo(4-toluidino)acetyl)carbohydrazonoyl)-2-naphthyl 4-chlorobenzoate
CAS 769153-05-1C27H20ClN3O4
1-(2-((4-Fluoroanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 2,4-dichlorobenzoate chemical structure, C26H16Cl2FN3O4, CAS 769151-12-4
1-(2-((4-Fluoroanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 2,4-dichlorobenzoate
CAS 769151-12-4C26H16Cl2FN3O4
1-((E)-{2-[2-(4-Ethoxyanilino)-2-oxoacetyl]hydrazono}methyl)-2-naphthyl 2,4-dichlorobenzoate chemical structure, C28H21Cl2N3O5, CAS 769150-72-3
1-((E)-{2-[2-(4-Ethoxyanilino)-2-oxoacetyl]hydrazono}methyl)-2-naphthyl 2,4-dichlorobenzoate
CAS 769150-72-3C28H21Cl2N3O5
1-(2-((4-Ethylanilino)(oxo)acetyl)carbohydrazonoyl)-2-naphthyl 3-methylbenzoate chemical structure, C29H25N3O4, CAS 769153-89-1
1-(2-((4-Ethylanilino)(oxo)acetyl)carbohydrazonoyl)-2-naphthyl 3-methylbenzoate
CAS 769153-89-1C29H25N3O4
1-(2-((4-Ethylanilino)(oxo)acetyl)carbohydrazonoyl)-2-naphthyl 4-methylbenzoate chemical structure, C29H25N3O4, CAS 769153-29-9
1-(2-((4-Ethylanilino)(oxo)acetyl)carbohydrazonoyl)-2-naphthyl 4-methylbenzoate
CAS 769153-29-9C29H25N3O4
1-(2-((4-Ethylanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 2,4-dichlorobenzoate chemical structure, C28H21Cl2N3O4, CAS 769153-42-6
1-(2-((4-Ethylanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 2,4-dichlorobenzoate
CAS 769153-42-6C28H21Cl2N3O4
1-(2-((4-Ethoxyanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 4-methoxybenzoate chemical structure, C29H25N3O6, CAS 769153-80-2
1-(2-((4-Ethoxyanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 4-methoxybenzoate
CAS 769153-80-2C29H25N3O6
1-(2-((4-Bromoanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 2,4-dichlorobenzoate chemical structure, C26H16BrCl2N3O4, CAS 767289-27-0
1-(2-((4-Bromoanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 2,4-dichlorobenzoate
CAS 767289-27-0C26H16BrCl2N3O4
1-(2-((4-Fluoroanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 4-methoxybenzoate chemical structure, C27H20FN3O5, CAS 767339-34-4
1-(2-((4-Fluoroanilino)(oxo)AC)carbohydrazonoyl)-2-naphthyl 4-methoxybenzoate
CAS 767339-34-4C27H20FN3O5
1-((E)-{2-[2-(4-Ethylanilino)-2-oxoacetyl]hydrazono}methyl)-2-naphthyl 4-ethoxybenzoate chemical structure, C30H27N3O5, CAS 769148-11-0
1-((E)-{2-[2-(4-Ethylanilino)-2-oxoacetyl]hydrazono}methyl)-2-naphthyl 4-ethoxybenzoate
CAS 769148-11-0C30H27N3O5
1-(2-(Oxo(4-toluidino)acetyl)carbohydrazonoyl)-2-naphthyl 4-ethoxybenzoate chemical structure, C29H25N3O5, CAS 769148-50-7
1-(2-(Oxo(4-toluidino)acetyl)carbohydrazonoyl)-2-naphthyl 4-ethoxybenzoate
CAS 769148-50-7C29H25N3O5